Regional tissue oxygen saturation: comparability and reproducibility of different devices.

UNLABELLED Comparability and reproducibility of different near-infrared spectroscopy devices measuring regional tissue oxygen saturation remain poor. Aim of the present study was to compare values and reproducibility of cerebral∕peripheral "tissue-oxygenation-index" (TOI; NIRO 300, Hamamatsu(®), Japan) with cerebral∕peripheral "regional-oxygen-saturation" (rSO; INVOS5100, Somanetics(®), USA), and to analyze the influence of quality criteria. METHODS cTOI and crSO2 were measured on the left forehead, pTOI and prSO2 were measured on the left calf. To analyse reproducibility, optodes were reapplied five times. A quality criterion was introduced for cTOI, crSO2 and prSO2. For pTOI quality criteria were introduced in combination with a venous occlusion technique. RESULTS Cerebral measurements were performed in 37 neonates. cTOI (72.7+∕-6.2%) was lower than crSO2 (83.3+∕-5.8%) (p < 0.001). The mean difference between cTOI and crSO2 was 10%. Mean standard deviations of cTOI and crSO2 were similar (cTOI: 4.9+∕-3.6; crSO2: 4.5+∕-2.6). Peripheral measurements were performed in 39 neonates. pTOI (66.0+∕-7.9%) was lower than prSO2 (82.0+∕-7.0%)(p < 0.001). The mean difference between pTOI and prSO2 was 15%. Mean standard deviations of pTOI (3.7+∕-2.6%) were lower than of prSO2 (5.0+∕-3.0%) (p = 0.047). CONCLUSION TOI values were significantly lower than rSO2 values, in cerebral and peripheral measurements. Reproducibility was higher for pTOI than for prSO2.

[1]  Gerhard Pichler,et al.  Combination of different noninvasive measuring techniques: a new approach to increase accuracy of peripheral near infrared spectroscopy. , 2009, Journal of biomedical optics.

[2]  Gorm Greisen,et al.  Precision of measurement of cerebral tissue oxygenation index using near-infrared spectroscopy in preterm neonates. , 2006, Journal of biomedical optics.

[3]  G. Pichler,et al.  Comparison of peripheral and cerebral tissue oxygenation index in neonates , 2009, Archives of Disease in Childhood Fetal and Neonatal Edition.

[4]  G. Greisen,et al.  Comparison of cerebral oxygen saturation in premature infants by near-infrared spatially resolved spectroscopy: observations on probe-dependent bias. , 2008, Journal of biomedical optics.

[5]  F. Jöbsis.  Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. , 1977, Science.

[6]  Gorm Greisen,et al.  Is near-infrared spectroscopy living up to its promises? , 2006, Seminars in fetal & neonatal medicine.

[7]  Markus Weiss,et al.  Measurement of cerebral oxygenation state in anaesthetized children using the INVOS 5100 cerebral oximeter , 2003, Paediatric anaesthesia.

[8]  D. Delpy,et al.  Optical pathlength measurements on adult head, calf and forearm and the head of the newborn infant using phase resolved optical spectroscopy. , 1995, Physics in medicine and biology.

[9]  M. Toet,et al.  Impact of Patent Ductus Arteriosus and Subsequent Therapy With Indomethacin on Cerebral Oxygenation in Preterm Infants , 2008, Pediatrics.

[10]  Gunnar Naulaers,et al.  Monitoring Neonatal Regional Cerebral Oxygen Saturation in Clinical Practice: Value and Pitfalls , 2008, Neonatology.

[11]  Martin Wolf,et al.  Progress of near-infrared spectroscopy and topography for brain and muscle clinical applications. , 2007, Journal of biomedical optics.

[12]  P. Klaritsch,et al.  Impact of Smoking during Pregnancy on Peripheral Tissue Oxygenation in Term Neonates , 2007, Neonatology.

[13]  C. Dani,et al.  Blood transfusions increase cerebral, splanchnic, and renal oxygenation in anemic preterm infants , 2010, Transfusion.

[14]  J. Leblanc,et al.  Comparison of Two Spatially Resolved NIRS Oxygenation Indices , 2002, Journal of Clinical Monitoring and Computing.

[15]  M. Weiss,et al.  Reproducibility of cerebral oxygenation measurement in neonates and infants in the clinical setting using the NIRO 300 oximeter* , 2005, Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies.

[16]  J. Salyer,et al.  Neonatal and pediatric pulse oximetry. , 2003, Respiratory care.

[17]  Jan Menke,et al.  Reproducibility of Cerebral Near Infrared Spectroscopy in Neonates , 2003, Neonatology.

[18]  S. Nicolson,et al.  Arterial and Venous Contributions to Near-infrared Cerebral Oximetry , 2000, Anesthesiology.

[19]  Martin Wolf,et al.  Advances in near-infrared spectroscopy to study the brain of the preterm and term neonate. , 2009, Clinics in perinatology.

[20]  M Smith,et al.  A comparison of cerebral oxygenation as measured by the NIRO 300 and the INVOS 5100 Near‐Infrared Spectrophotometers , 2002, Anaesthesia.

[21]  G. Pichler,et al.  Forearm and calf tissue oxygenation in term neonates measured with near-infrared spectroscopy. , 2007, The journal of physiological sciences : JPS.

[22]  S A Spencer,et al.  Measurement of peripheral oxygen utilisation in neonates using near infrared spectroscopy: comparison between arterial and venous occlusion methods. , 2000, Early human development.

[23]  Hitoshi Furuya,et al.  A Comparison of the INVOS 4100 and the NIRO 300 Near-Infrared Spectrophotometers , 2002, Anesthesia and analgesia.

[24]  M. Wolf,et al.  Recommendations to Increase the Validity and Comparability of Peripheral Measurements by Near Infrared Spectroscopy in Neonates , 2008, Neonatology.

[25]  P. Klaritsch,et al.  Peripheral oxygenation in term neonates , 2007, Archives of Disease in Childhood - Fetal and Neonatal Edition.

[26]  M. Ferrari,et al.  Foot Pulse Oximeter Perfusion Index Correlates with Calf Muscle Perfusion Measured by Near-Infrared Spectroscopy in Healthy Neonates , 2005, Journal of Perinatology.

[27]  Felix Berger,et al.  Comparison of different near‐infrared spectroscopic cerebral oxygenation indices with central venous and jugular venous oxygenation saturation in children , 2007, Paediatric anaesthesia.