Biodegradable cross-linked chitosan nanoparticles improve anti-Candida and anti-biofilm activity of TistH, a peptide identified in the venom gland of the Tityus stigmurus scorpion.

[1]  Ruta Galoburda,et al.  FTIR spectroscopy studies of high pressure-induced changes in pork macromolecular structure , 2019, Journal of Molecular Structure.

[2]  V. H. Sarmento,et al.  Tailoring microstructural, drug release properties, and antichagasic efficacy of biocompatible oil‐in‐water benznidazol‐loaded nanoemulsions , 2019, International journal of pharmaceutics.

[3]  D. Tambourgi,et al.  A biotechnological approach to immunotherapy: Antivenom against Crotalus durissus cascavella snake venom produced from biodegradable nanoparticles. , 2018, International journal of biological macromolecules.

[4]  B. L. C. Gondim,et al.  Effect of chitosan nanoparticles on the inhibition of Candida spp. biofilm on denture base surface. , 2018, Archives of oral biology.

[5]  L. Soares,et al.  Influence of Eugenia uniflora Extract on Adhesion to Human Buccal Epithelial Cells, Biofilm Formation, and Cell Surface Hydrophobicity of Candida spp. from the Oral Cavity of Kidney Transplant Recipients , 2018, Molecules.

[6]  D. Tambourgi,et al.  Antivenom Production against Bothrops jararaca and Bothrops erythromelas Snake Venoms Using Cross-Linked Chitosan Nanoparticles as an Immunoadjuvant , 2018, Toxins.

[7]  Andrea Ragusa,et al.  Neuroprotective Investigation of Chitosan Nanoparticles for Dopamine Delivery , 2018 .

[8]  Y. Ho,et al.  Antibacterial Effects of Chitosan/Cationic Peptide Nanoparticles , 2018, Nanomaterials.

[9]  C. Dass,et al.  The role of chitosan on oral delivery of peptide-loaded nanoparticle formulation , 2017, Journal of drug targeting.

[10]  C. Tan,et al.  Improved In Vivo Efficacy of Anti-Hypertensive Biopeptides Encapsulated in Chitosan Nanoparticles Fabricated by Ionotropic Gelation on Spontaneously Hypertensive Rats , 2017, Nanomaterials.

[11]  S. Vicente,et al.  Chitosan nanoparticles as alternative anti-staphylococci agents: Bactericidal, antibiofilm and antiadhesive effects. , 2017, Materials science & engineering. C, Materials for biological applications.

[12]  M. F. Fernandes-Pedrosa,et al.  Self-assembled scorpion venom proteins cross-linked chitosan nanoparticles for use in the immunotherapy , 2017 .

[13]  A. M. Dos Santos-Silva,et al.  Designing structural features of novel benznidazole-loaded cationic nanoparticles for inducing slow drug release and improvement of biological efficacy. , 2017, Materials science & engineering. C, Materials for biological applications.

[14]  W. P. Silva-Rocha,et al.  Characterization of virulence factors of vaginal and anal isolates of Candida albicans sequentially obtained from patients with vulvovaginal candidiasis in north-east Brazil. , 2017, Journal de mycologie medicale.

[15]  M. Rezayat,et al.  A New Approach to Antivenom Preparation Using Chitosan Nanoparticles Containing EchisCarinatus Venom as A Novel Antigen Delivery System , 2017, Iranian journal of pharmaceutical research : IJPR.

[16]  A. Fusco-Almeida,et al.  Antifungal Therapy: New Advances in the Understanding and Treatment of Mycosis , 2017, Front. Microbiol..

[17]  M. F. Fernandes-Pedrosa,et al.  Cationic functionalized biocompatible polylactide nanoparticles for slow release of proteins , 2017 .

[18]  Rajat Gupta,et al.  Nanoparticle formulation having ability to control the release of protein for drug delivery application. , 2017, Materials science & engineering. C, Materials for biological applications.

[19]  K. Ramkumar,et al.  Preparation of collagen peptide functionalized chitosan nanoparticles by ionic gelation method: An effective carrier system for encapsulation and release of doxorubicin for cancer drug delivery. , 2017, Materials science & engineering. C, Materials for biological applications.

[20]  M. F. Fernandes-Pedrosa,et al.  Characterization of TistH, a multifunctional peptide from the scorpion Tityus stigmurus: Structure, cytotoxicity and antimicrobial activity. , 2016, Toxicon : official journal of the International Society on Toxinology.

[21]  N. Al-Dhabi,et al.  Delivery of chitosan/dsRNA nanoparticles for silencing of wing development vestigial (vg) gene in Aedes aegypti mosquitoes. , 2016, International journal of biological macromolecules.

[22]  Tarek A. Ahmed,et al.  Preparation, characterization, and potential application of chitosan, chitosan derivatives, and chitosan metal nanoparticles in pharmaceutical drug delivery , 2016, Drug design, development and therapy.

[23]  Shun-Hsien Chang,et al.  pH Effects on solubility, zeta potential, and correlation between antibacterial activity and molecular weight of chitosan. , 2015, Carbohydrate polymers.

[24]  Ahmed Jalal Khan Chowdhury,et al.  Impact of chitosan composites and chitosan nanoparticle composites on various drug delivery systems: A review , 2014, Journal of food and drug analysis.

[25]  M. F. Fernandes-Pedrosa,et al.  Homology modeling, vasorelaxant and bradykinin-potentiating activities of a novel hypotensin found in the scorpion venom from Tityus stigmurus. , 2015, Toxicon : official journal of the International Society on Toxinology.

[26]  M. M. Melo,et al.  General characterization of Tityus fasciolatus scorpion venom. Molecular identification of toxins and localization of linear B-cell epitopes. , 2015, Toxicon : official journal of the International Society on Toxinology.

[27]  H. Tajmir-Riahi,et al.  The role of polymer size and hydrophobic end-group in PEG-protein interaction. , 2015, Colloids and surfaces. B, Biointerfaces.

[28]  H. Tajmir-Riahi,et al.  Effect of polymer molecular weight on chitosan-protein interaction. , 2015, Colloids and surfaces. B, Biointerfaces.

[29]  G. M. Chaves,et al.  Genetic relatedness among vaginal and anal isolates of Candida albicans from women with vulvovaginal candidiasis in north-east Brazil. , 2014, Journal of medical microbiology.

[30]  V. L. Pinto,et al.  Scorpionism in Brazil in the years 2000 to 2012 , 2014, Journal of Venomous Animals and Toxins including Tropical Diseases.

[31]  A. Almaaytah,et al.  Scorpion venom peptides with no disulfide bridges: A review , 2014, Peptides.

[32]  Gerard D. Wright Something old, something new: revisiting natural products in antibiotic drug discovery. , 2014, Canadian journal of microbiology.

[33]  S. Vimal,et al.  Chitosan tripolyphosphate (CS/TPP) nanoparticles: preparation, characterization and application for gene delivery in shrimp. , 2013, Acta tropica.

[34]  Paolo Blasi,et al.  Chitosan nanoparticles: preparation, size evolution and stability. , 2013, International journal of pharmaceutics.

[35]  S. Low,et al.  Characterization of magnetic nanoparticle by dynamic light scattering , 2013, Nanoscale Research Letters.

[36]  Ran Wei,et al.  Two peptides, TsAP-1 and TsAP-2, from the venom of the Brazilian yellow scorpion, Tityus serrulatus: evaluation of their antimicrobial and anticancer activities. , 2013, Biochimie.

[37]  S. Vimal,et al.  Synthesis and Characterization of Chitosan Tripolyphosphate Nanoparticles and its Encapsulation Efficiency Containing Russell's Viper Snake Venom , 2013, Journal of biochemical and molecular toxicology.

[38]  D. Zaharoff,et al.  The effect of antigen encapsulation in chitosan particles on uptake, activation and presentation by antigen presenting cells. , 2013, Biomaterials.

[39]  D. Betbeder,et al.  Airway delivery of peptides and proteins using nanoparticles. , 2013, Biomaterials.

[40]  David W. Denning,et al.  Hidden Killers: Human Fungal Infections , 2012, Science Translational Medicine.

[41]  M. F. Fernandes-Pedrosa,et al.  Serum production against Tityus serrulatus scorpion venom using cross-linked chitosan nanoparticles as immunoadjuvant. , 2012, Toxicon : official journal of the International Society on Toxinology.

[42]  V. B. Konkimalla,et al.  Poly-є-caprolactone based formulations for drug delivery and tissue engineering: A review. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[43]  M. F. Fernandes-Pedrosa,et al.  Profiling the resting venom gland of the scorpion Tityus stigmurus through a transcriptomic survey , 2012, BMC Genomics.

[44]  M. Saunders,et al.  Uptake and cytotoxicity of chitosan nanoparticles in human liver cells. , 2010, Toxicology and applied pharmacology.

[45]  Ming Kong,et al.  Antimicrobial properties of chitosan and mode of action: a state of the art review. , 2010, International journal of food microbiology.

[46]  S. Pelloso,et al.  Antifungal activity of propolis extract against yeasts isolated from vaginal exudates. , 2010, Journal of alternative and complementary medicine.

[47]  A. Ezabadi,et al.  Preparation of chitosan nanoparticles containing Naja naja oxiana snake venom. , 2010, Nanomedicine : nanotechnology, biology, and medicine.

[48]  H. Tajmir-Riahi,et al.  Complexes of dendrimers with bovine serum albumin. , 2010, Biomacromolecules.

[49]  Maria Jose Alonso,et al.  Ionically crosslinked chitosan/tripolyphosphate nanoparticles for oligonucleotide and plasmid DNA delivery. , 2009, International journal of pharmaceutics.

[50]  D. L. Wetzel,et al.  Innovative FT-IR imaging of protein film secondary structure before and after heat treatment. , 2009, Journal of agricultural and food chemistry.

[51]  John Thomas,et al.  Oral delivery of DNA construct using chitosan nanoparticles to protect the shrimp from white spot syndrome virus (WSSV). , 2009, Fish & shellfish immunology.

[52]  I. Kang,et al.  Evaluation of the effects of biodegradable nanoparticles on a vaccine delivery system using AFM, SEM, and TEM. , 2008, Ultramicroscopy.

[53]  Peter Eaton,et al.  Atomic force microscopy study of the antibacterial effects of chitosans on Escherichia coli and Staphylococcus aureus. , 2008, Ultramicroscopy.

[54]  Paul E. West,et al.  A comparison of atomic force microscopy (AFM) and dynamic light scattering (DLS) methods to characterize nanoparticle size distributions , 2008 .

[55]  A. G. Oliveira,et al.  Thermal analysis of biodegradable microparticles containing ciprofloxacin hydrochloride obtained by spray drying technique , 2008 .

[56]  V. Torchilin Targeted pharmaceutical nanocarriers for cancer therapy and imaging , 2007, The AAPS Journal.

[57]  D. Elgar,et al.  Southern African scorpion toxins: an overview. , 2008, Toxicon : official journal of the International Society on Toxinology.

[58]  Tao Wang,et al.  Chitosan nanoparticle as protein delivery carrier--systematic examination of fabrication conditions for efficient loading and release. , 2007, Colloids and surfaces. B, Biointerfaces.

[59]  S. Stepanović,et al.  Quantification of biofilm in microtiter plates: overview of testing conditions and practical recommendations for assessment of biofilm production by staphylococci , 2007, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[60]  B. Arthington-Skaggs,et al.  Paradoxical Growth Effect of Caspofungin Observed on Biofilms and Planktonic Cells of Five Different Candida Species , 2007, Antimicrobial Agents and Chemotherapy.

[61]  B. Shekunov,et al.  Particle Size Analysis in Pharmaceutics: Principles, Methods and Applications , 2007, Pharmaceutical Research.

[62]  P. Carreau,et al.  Viscoelastic properties of chitosan solutions: Effect of concentration and ionic strength , 2006 .

[63]  Xiaojun Ma,et al.  The enzymatic degradation and swelling properties of chitosan matrices with different degrees of N-acetylation. , 2005, Carbohydrate research.

[64]  Tao Wang,et al.  Modulation of surface charge, particle size and morphological properties of chitosan-TPP nanoparticles intended for gene delivery. , 2005, Colloids and surfaces. B, Biointerfaces.

[65]  Zi-rong Xu,et al.  Cytotoxic activities of chitosan nanoparticles and copper-loaded nanoparticles. , 2005, Bioorganic & medicinal chemistry letters.

[66]  A. Bozkır,et al.  Chitosan Nanoparticles for Plasmid DNA Delivery: Effect of Chitosan Molecular Structure on Formulation and Release Characteristics , 2004, Drug delivery.

[67]  Robert Gurny,et al.  Structure and interactions in chitosan hydrogels formed by complexation or aggregation for biomedical applications. , 2004, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[68]  L. Samaranayake,et al.  Biofilm-Forming Ability of Candida albicans Is Unlikely To Contribute to High Levels of Oral Yeast Carriage in Cases of Human Immunodeficiency Virus Infection , 2003, Journal of Clinical Microbiology.

[69]  G. Quindós,et al.  Adherence of Candida albicans and Candida dubliniensis to buccal and vaginal cells. , 2003, Revista iberoamericana de micologia.

[70]  Yumin Du,et al.  Effect of molecular structure of chitosan on protein delivery properties of chitosan nanoparticles. , 2003, International journal of pharmaceutics.

[71]  Hui Xu,et al.  Bioadhesive polysaccharide in protein delivery system: chitosan nanoparticles improve the intestinal absorption of insulin in vivo. , 2002, International journal of pharmaceutics.

[72]  Hyun-Jin Park,et al.  The effect of carboxymethyl-chitosan on proliferation and collagen secretion of normal and keloid skin fibroblasts. , 2002, Biomaterials.

[73]  E J Wood,et al.  The effect of chitin and chitosan on the proliferation of human skin fibroblasts and keratinocytes in vitro. , 2001, Biomaterials.

[74]  Y Wang,et al.  Chitosan-DNA nanoparticles as gene carriers: synthesis, characterization and transfection efficiency. , 2001, Journal of controlled release : official journal of the Controlled Release Society.

[75]  T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. , 1983, Journal of immunological methods.