Insight into the significance of blood flow inside stenosis coronary jointed with bypass vein: The case of anemic, normal, and hypertensive individuals

BACKGROUND AND OBJECTIVE Recently, transplant of bypass vein is employed to charge blood fluid inside vein after stenosis position. Because, bypass vein can compensate consequences of stenosis in reducing blood flow within vessels. Therefore, analyses of shear stress for anemia, normal, and hypertensive individuals can prepare a valuable understanding in mechanical geometry which is applicable to design of transplantation especially for critical condition of shear stress. In this work, the transplantation of vessels is simulated in Fluent software, and user-defined function is used to indicate the blood properties as a non-Newtonian fluid based on Carreau fluid model. METHODS Generally, shear stress profiles are studied for three cases of anemia, normal, and hypertensive individuals. Also, stenosis with the severity of 30% is simulated before the junction of host and grafted vessels. Finally, the results of shear stress on the walls (WSS) are reported with respect to three divided sections. Section one related to the distance from the stenosis position to the joining position of veins. Section two is the complete distance of the transplantation of veins, which blood flows are mixed. Section three is related to the distance after transplantation of host and grafted vessels. RESULTS It was reported that flow separation causes the velocity of blood flow increases, which enhances shear stress. Moreover, increasing velocity in a hypertensive individual can exacerbate the shear stress. Maximum shear stress is as much as 105 Pa, 125 Pa, and 220 Pa in order of anemia, normal, and hypertensive individuals with abbreviations of LHD, NHD, and HHD, orderly. CONCLUSIONS A comparison of maximum shear stress values in the Heel and Toe section showed that transplantation of veins can be a critical position of failure, which is introduced potentially as a sensible position for medical treatment and related surgeries.

[1]  Young I Cho,et al.  Effect of blood viscosity on oxygen transport in residual stenosed artery following angioplasty. , 2008, Journal of biomechanical engineering.

[2]  Loke Kok Foong,et al.  Numerical simulation of blood flow inside an artery under applying constant heat flux using Newtonian and non-Newtonian approaches for biomedical engineering , 2020, Comput. Methods Programs Biomed..

[3]  D. Toghraie,et al.  Prediction of boiling flow characteristics in rough and smooth microchannels using molecular dynamics simulation: Investigation the effects of boundary wall temperatures , 2020 .

[4]  J. Poulter.  NUMERICAL STUDY OF PULSATILE BLOOD FLOW IN THE CORONARY SYSTEM WITH THE RCA BYPASS GRAFT , 2013 .

[5]  Omid Ali Akbari,et al.  The effect of rib shape on the behavior of laminar flow of oil/MWCNT nanofluid in a rectangular microchannel , 2018, Journal of Thermal Analysis and Calorimetry.

[6]  N. Kaplan.  Hypertension: prevalence, risks, and effect of therapy. , 1983, Annals of internal medicine.

[7]  Loke Kok Foong,et al.  Numerical study for blood rheology inside an artery: The effects of stenosis and radius on the flow behavior , 2020, Comput. Methods Programs Biomed..

[8]  D. Toghraie,et al.  NUMERICAL SIMULATION OF BLOOD FLOW IN HEALTHY ARTERIES BY USE OF THE SISKO MODEL , 2016 .

[9]  D. Toghraie,et al.  Molecular dynamic simulation to study the effects of roughness elements with cone geometry on the boiling flow inside a microchannel , 2019, International Journal of Heat and Mass Transfer.

[10]  Daniel W. Jones,et al.  The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. , 2003, JAMA.

[11]  Davood Toghraie,et al.  Blood flow analysis inside different arteries using non-Newtonian Sisko model for application in biomedical engineering , 2020, Comput. Methods Programs Biomed..

[12]  R. Collins,et al.  Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies , 2002, The Lancet.

[13]  Omid Ali Akbari,et al.  The numerical modeling of water/FMWCNT nanofluid flow and heat transfer in a backward-facing contracting channel , 2018 .

[14]  Loke Kok Foong,et al.  Numerical investigation of non-Newtonian blood flow within an artery with cone shape of stenosis in various stenosis angles , 2020, Comput. Methods Programs Biomed..

[15]  M. Afrand,et al.  Effects of surface roughness with the spherical shape on the fluid flow of argon atoms flowing into the microchannel, under boiling condition using molecular dynamic simulation , 2020 .

[16]  Mahmud Ashrafizaadeh,et al.  A comparison of non-Newtonian models for lattice Boltzmann blood flow simulations , 2009, Comput. Math. Appl..

[17]  B. Rosner,et al.  Age-specific correlation analysis of longitudinal blood pressure data. , 1977, American journal of epidemiology.

[18]  S. Saleem,et al.  Heat transfer in the flow of blood-gold Carreau nanofluid induced by partial slip and buoyancy , 2018, Heat Transfer-Asian Research.

[19]  Hassan Karimi-Maleh,et al.  Electrochemical Sensors, a Bright Future in the Fabrication of Portable Kits in Analytical Systems. , 2019, Chemical record.

[20]  Omid Ali Akbari,et al.  Investigating the effect of nanoparticles diameter on turbulent flow and heat transfer properties of non-Newtonian carboxymethyl cellulose/CuO fluid in a microtube , 2019, International Journal of Numerical Methods for Heat & Fluid Flow.

[21]  M. Taher,et al.  A nanostructure voltammetric platform amplified with ionic liquid for determination of tert-butylhydroxyanisole in the presence kojic acid , 2019, Journal of Food Measurement and Characterization.

[22]  N. S. Vlachos,et al.  Numerical modeling of simulated blood flow in idealized composite arterial coronary grafts: steady state simulations. , 2007, Journal of biomechanics.

[23]  I. Pop,et al.  Numerical exploration of a non-Newtonian Carreau fluid flow driven by catalytic surface reactions on an upper horizontal surface of a paraboloid of revolution, buoyancy and stretching at the free stream , 2017 .

[24]  M. Afrand,et al.  Empowering the boiling condition of Argon flow inside a rectangular microchannel with suspending Silver nanoparticles by using of molecular dynamics simulation , 2019 .

[25]  M. Rahimi-Gorji,et al.  Quadratic convective transport of dusty Casson and dusty Carreau fluids past a stretched surface with nonlinear thermal radiation, convective condition and non-uniform heat source/sink , 2019 .

[26]  A. Tirosh,et al.  Blood-pressure categories in adolescence predict development of hypertension in accordance with the European guidelines. , 2007, American journal of hypertension.

[27]  R. Pietrabissa,et al.  Simulation study of the fluid dynamics of aorto-coronary bypass. , 1990, Journal of biomedical engineering.

[28]  D. Toghraie,et al.  The effects of suspending Copper nanoparticles into Argon base fluid inside a microchannel under boiling flow condition by using of molecular dynamic simulation , 2019, Journal of Molecular Liquids.

[29]  Omid Ali Akbari,et al.  Application of lattice Boltzmann method and spinodal decomposition phenomenon for simulating two-phase thermal flows , 2018, Physica A: Statistical Mechanics and its Applications.

[30]  Alvaro Valencia,et al.  Non-Newtonian blood flow dynamics in a right internal carotid artery with a saccular aneurysm , 2006 .

[31]  N. Nelson,et al.  Blood pressure characteristics of a select group of North American males, followed for 20 years. , 1972, Canadian Medical Association journal.

[32]  Daniel W. Jones,et al.  Seventh report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure. , 2003, Hypertension.

[33]  H. Karimi-Maleh,et al.  Simultaneous determination of cholesterol, ascorbic acid and uric acid as three essential biological compounds at a carbon paste electrode modified with copper oxide decorated reduced graphene oxide nanocomposite and ionic liquid. , 2020, Journal of colloid and interface science.