Cleaning Validation and its importance in Pharmaceutical Industry

Cleaning validation is a documented process that proves the effectiveness and consistency in cleaning a pharmaceutical production equipment1. Validations of equipment cleaning procedures are mainly used in pharmaceutical industries to prevent cross contamination and adulteration of drug products hence is critically important2. The prime purpose of validating a cleaning process is to ensure compliance with federal and other standard regulations. The most important benefit of conducting such a validation work is the identification and correction of potential problems previously unsuspected, which could compromise the safety, efficacy or quality of subsequent batches of drug product produced within the equipment. This paper provides a review of the current trends in cleaning validation and its related importance.

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