How synapses can enhance sensibility of a neural network

Abstract In this work, we study the dynamic range in a neural network modelled by cellular automaton. We consider deterministic and non-deterministic rules to simulate electrical and chemical synapses. Chemical synapses have an intrinsic time-delay and are susceptible to parameter variations guided by learning Hebbian rules of behaviour. The learning rules are related to neuroplasticity that describes change to the neural connections in the brain. Our results show that chemical synapses can abruptly enhance sensibility of the neural network, a manifestation that can become even more predominant if learning rules of evolution are applied to the chemical synapses.

[1]  Murilo S. Baptista,et al.  Network and external perturbation induce burst synchronisation in cat cerebral cortex , 2016, Commun. Nonlinear Sci. Numer. Simul..

[2]  I. K. Wood,et al.  Neuroscience: Exploring the brain , 1996 .

[3]  D. Feldman,et al.  Timing-Based LTP and LTD at Vertical Inputs to Layer II/III Pyramidal Cells in Rat Barrel Cortex , 2000, Neuron.

[4]  Alan M. Frieze,et al.  Random graphs , 2006, SODA '06.

[5]  G. Turrigiano,et al.  Rapid Synaptic Scaling Induced by Changes in Postsynaptic Firing , 2008, Neuron.

[6]  Denis Milan,et al.  Design of a High Density SNP Genotyping Assay in the Pig Using SNPs Identified and Characterized by Next Generation Sequencing Technology , 2009, PloS one.

[7]  K. Lashley,et al.  The Behavioristic Interpretation of Consciousness I , 2018 .

[8]  Leonardo L. Gollo,et al.  Signal integration enhances the dynamic range in neuronal systems. , 2012, Physical review. E, Statistical, nonlinear, and soft matter physics.

[9]  Shawn R. Olsen,et al.  Sensory processing in the Drosophila antennal lobe increases reliability and separability of ensemble odor representations , 2007, Nature Neuroscience.

[10]  W. Regehr,et al.  Short-term synaptic plasticity. , 2002, Annual review of physiology.

[11]  Andrej Kral,et al.  Developmental neuroplasticity after cochlear implantation , 2012, Trends in Neurosciences.

[12]  John von Neumann,et al.  Theory Of Self Reproducing Automata , 1967 .

[13]  G. E. Alexander,et al.  Neuron Activity Related to Short-Term Memory , 1971, Science.

[14]  L. Abbott,et al.  Synaptic plasticity: taming the beast , 2000, Nature Neuroscience.

[15]  Frank W. Stahnisch,et al.  Santiago Ramón y Cajal's concept of neuronal plasticity: the ambiguity lives on , 2002, Trends in Neurosciences.

[16]  O. Kinouchi,et al.  Optimal dynamical range of excitable networks at criticality , 2006, q-bio/0601037.

[17]  Dante R Chialvo,et al.  Brain organization into resting state networks emerges at criticality on a model of the human connectome. , 2012, Physical review letters.

[18]  Beatriz E. P. Mizusaki,et al.  Learning and retrieval behavior in recurrent neural networks with pre-synaptic dependent homeostatic plasticity , 2017 .

[19]  G. Bi,et al.  Synaptic Modifications in Cultured Hippocampal Neurons: Dependence on Spike Timing, Synaptic Strength, and Postsynaptic Cell Type , 1998, The Journal of Neuroscience.

[20]  Anu Sharma,et al.  Plasticity in the developing auditory cortex: evidence from children with sensorineural hearing loss and auditory neuropathy spectrum disorder. , 2012, Journal of the American Academy of Audiology.

[21]  Toru Nakamura,et al.  Resting Network Plasticity Following Brain Injury , 2009, PloS one.

[22]  M. Baptista,et al.  Complementary action of chemical and electrical synapses to perception , 2014, 1412.1369.

[23]  Peter A. Tass,et al.  Self-organized noise resistance of oscillatory neural networks with spike timing-dependent plasticity , 2013, Scientific Reports.

[24]  T. Robinson,et al.  Brain Plasticity and Behavior , 2003, Annual review of psychology.

[25]  A. Hodgkin,et al.  A quantitative description of membrane current and its application to conduction and excitation in nerve , 1952, The Journal of physiology.

[26]  Farzan Nadim,et al.  Short-Term Dynamics of a Mixed Chemical and Electrical Synapse in a Rhythmic Network , 2003, The Journal of Neuroscience.

[27]  Robert B. Northrop Introduction to Dynamic Modeling of Neuro-Sensory Systems , 2000 .

[28]  Frederico A. C. Azevedo,et al.  How many neurons do you have? Some dogmas of quantitative neuroscience under revision , 2012, The European journal of neuroscience.

[29]  J. Hindmarsh,et al.  A model of neuronal bursting using three coupled first order differential equations , 1984, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[30]  Beatriz E. P. Mizusaki,et al.  Spike timing analysis in neural networks with unsupervised synaptic plasticity , 2013 .

[31]  Chris G. Antonopoulos,et al.  Spike timing-dependent plasticity induces non-trivial topology in the brain , 2016, Neural Networks.

[32]  L. Merabet,et al.  The plastic human brain cortex. , 2005, Annual review of neuroscience.

[33]  Antonio M. Batista,et al.  Dynamic range in a neuron network with electrical and chemical synapses , 2014, Commun. Nonlinear Sci. Numer. Simul..

[34]  Stephen Wolfram,et al.  Universality and complexity in cellular automata , 1983 .

[35]  S. R. Lopes,et al.  Dynamic range in small-world networks of Hodgkin-Huxley neurons with chemical synapses , 2014 .

[36]  A. Craig A new view of pain as a homeostatic emotion , 2003, Trends in Neurosciences.

[37]  Leonardo Gregory Brunnet,et al.  Physica a Model Architecture for Associative Memory in a Neural Network of Spiking Neurons , 2022 .

[38]  Raoul Borges,et al.  Effects of the spike timing-dependent plasticity on the synchronisation in a random Hodgkin-Huxley neuronal network , 2015, Commun. Nonlinear Sci. Numer. Simul..

[39]  Mahdi Jalili,et al.  Collective behavior of interacting locally synchronized oscillations in neuronal networks , 2012 .

[40]  E. Capaldi,et al.  The organization of behavior. , 1992, Journal of applied behavior analysis.

[41]  N. Rulkov Regularization of synchronized chaotic bursts. , 2000, Physical review letters.

[42]  Hannah Monyer,et al.  Electrical synapses: a dynamic signaling system that shapes the activity of neuronal networks. , 2004, Biochimica et biophysica acta.

[43]  M. Alexander,et al.  Principles of Neural Science , 1981 .

[44]  M S Baptista,et al.  Combined effect of chemical and electrical synapses in Hindmarsh-Rose neural networks on synchronization and the rate of information. , 2009, Physical review. E, Statistical, nonlinear, and soft matter physics.