Proprotein Convertase Activity Contributes to the Processing of the Alzheimer's β‐Amyloid Precursor Protein in Human Cells: Evidence for a Role of the Prohormone Convertase PC7 in the Constitutive ‐Secretase Pathway
暂无分享,去创建一个
[1] F. Checler. Presenilins: structural aspects and posttranslational events. , 1999, Molecular neurobiology.
[2] E. Kojro,et al. Constitutive and regulated alpha-secretase cleavage of Alzheimer's amyloid precursor protein by a disintegrin metalloprotease. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[3] D. Campion,et al. Unusual phenotypic alteration of β amyloid precursor protein (βAPP) maturation by a new Val-715 → Met βAPP-770 mutation responsible for probable early-onset Alzheimer’s disease , 1999 .
[4] S. Gandy,et al. Involvement of Cell Surface Glycosyl-phosphatidylinositol-linked Aspartyl Proteases in α-Secretase-type Cleavage and Ectodomain Solubilization of Human Alzheimer β-Amyloid Precursor Protein in Yeast* , 1998, The Journal of Biological Chemistry.
[5] P. Greengard,et al. Generation and Regulation of β‐Amyloid Peptide Variants by Neurons , 1998 .
[6] Joseph D. Buxbaum,et al. Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor* , 1998, The Journal of Biological Chemistry.
[7] A. Israël,et al. The Notch1 receptor is cleaved constitutively by a furin-like convertase. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[8] G. Thomas,et al. alpha1-Antitrypsin Portland, a bioengineered serpin highly selective for furin: application as an antipathogenic agent. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[9] N. Seidah,et al. Precursor Convertases: An Evolutionary Ancient, Cell‐Specific, Combinatorial Mechanism Yielding Diverse Bioactive Peptides and Proteins , 1998, Annals of the New York Academy of Sciences.
[10] F. Checler,et al. α‐Secretase‐Derived Product of β‐Amyloid Precursor Protein Is Decreased by Presenilin 1 Mutations Linked to Familial Alzheimer's Disease , 1997 .
[11] N. Seidah,et al. α1-Antitrypsin Portland Inhibits Processing of Precursors Mediated by Proprotein Convertases Primarily within the Constitutive Secretory Pathway* , 1997, Journal of Biological Chemistry.
[12] J. Buxbaum,et al. Characterization of New Polyclonal Antibodies Specific for 40 and 42 Amino Acid-Long Amyloid β Peptides: Their Use to Examine the Cell Biology of Presenilins and the Immunohistochemistry of Sporadic Alzheimer’s Disease and Cerebral Amyloid Angiopathy Cases , 1997, Molecular medicine.
[13] N. Seidah,et al. In Vitro Characterization of the Novel Proprotein Convertase PC7* , 1997, The Journal of Biological Chemistry.
[14] John Hardy,et al. Amyloid, the presenilins and Alzheimer's disease , 1997, Trends in Neurosciences.
[15] F. Checler,et al. Proteasome Contributes to the α‐Secretase Pathway of Amyloid Precursor Protein in Human Cells , 1997 .
[16] D. Borchelt,et al. Endoproteolysis of Presenilin 1 and Accumulation of Processed Derivatives In Vivo , 1996, Neuron.
[17] N. Seidah,et al. cDNA structure, tissue distribution, and chromosomal localization of rat PC7, a novel mammalian proprotein convertase closest to yeast kexin-like proteinases. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[18] D. Selkoe,et al. The Swedish mutation causes early-onset Alzheimer's disease by β-secretase cleavage within the secretory pathway , 1995, Nature Medicine.
[19] F. Checler. Processing of the β‐Amyloid Precursor Protein and Its Regulation in Alzheimer's Disease , 1995 .
[20] B. de Strooper,et al. Amyloid precursor protein is not processed by furin, PACE 4, PC1/3, PC2, PC4 and PC5/6 of the furin family of proprotein processing enzymes. , 1995, Biochimica et biophysica acta.
[21] C. Maury,et al. Molecular pathogenesis of beta-amyloidosis in Alzheimer's disease and other cerebral amyloidoses. , 1995, Laboratory investigation; a journal of technical methods and pathology.
[22] J Carter,et al. Molecular Pathology of Alzheimer's Disease , 2013 .
[23] D. Selkoe,et al. Normal and abnormal biology of the beta-amyloid precursor protein. , 1994, Annual review of neuroscience.
[24] D. Selkoe,et al. Cellular processing of β-amyloid precursor protein and the genesis of amyloid β-peptide , 1993, Cell.
[25] L. Thomas,et al. Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant. , 1993, The Journal of biological chemistry.
[26] J. Shioi,et al. Evidence for intracellular cleavage of the Alzheimer's amyloid precursor in PC12 cells , 1992, Journal of neuroscience research.
[27] S. Sisodia. Beta-amyloid precursor protein cleavage by a membrane-bound protease. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[28] B T Hyman,et al. Kunitz Protease Inhibitor‐Containing Amyloid β Protein Precursor Immunoreactivity in Alzheimer's Disease , 1992, Journal of neuropathology and experimental neurology.
[29] C. Masters,et al. Amyloid plaque core protein in Alzheimer disease and Down syndrome. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[30] G. Glenner,et al. Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein. , 1984, Biochemical and biophysical research communications.
[31] M. M. Bradford. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.