Global chromatin compaction limits the strength of the DNA damage response
暂无分享,去创建一个
Seung-Min Yang | M. Blasco | M. Cuadrado | Bárbara Martínez-Pastor | O. Fernandez-Capetillo | A. Skoultchi | Yuhong Fan | M. Murga | Rebeca Soria | I. Jaco
[1] Mark W. Dewhirst,et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response , 2006, Nature.
[2] Y. Shiloh,et al. Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway , 2006, Nature Cell Biology.
[3] M. Fraga,et al. DNA methyltransferases control telomere length and telomere recombination in mammalian cells , 2006, Nature Cell Biology.
[4] C. Woodcock,et al. Role of linker histone in chromatin structure and function: H1 stoichiometry and nucleosome repeat length , 2006, Chromosome Research.
[5] M. Cuadrado,et al. ATM regulates ATR chromatin loading in response to DNA double-strand breaks , 2006, The Journal of experimental medicine.
[6] A. Stein,et al. Histone H1 Depletion in Mammals Alters Global Chromatin Structure but Causes Specific Changes in Gene Regulation , 2005, Cell.
[7] Huichen Wang,et al. ATR Affecting Cell Radiosensitivity Is Dependent on Homologous Recombination Repair but Independent of Nonhomologous End Joining , 2004, Cancer Research.
[8] Michel Nussenzweig,et al. H2AX: the histone guardian of the genome. , 2004, DNA repair.
[9] Kai Rothkamm,et al. A Double-Strand Break Repair Defect in ATM-Deficient Cells Contributes to Radiosensitivity , 2004, Cancer Research.
[10] Y. Tsujimoto,et al. Involvement of Histone H1.2 in Apoptosis Induced by DNA Double-Strand Breaks , 2003, Cell.
[11] T. Magnuson,et al. H1 Linker Histones Are Essential for Mouse Development and Affect Nucleosome Spacing In Vivo , 2003, Molecular and Cellular Biology.
[12] S. Jackson,et al. Suppression of homologous recombination by the Saccharomyces cerevisiae linker histone. , 2003, Molecular cell.
[13] Gabriele Müller,et al. Trichostatin A-induced histone acetylation causes decondensation of interphase chromatin , 2003, Journal of Cell Science.
[14] J. Milner,et al. p53 is a chromatin accessibility factor for nucleotide excision repair of DNA damage , 2003, The EMBO journal.
[15] M. Kastan,et al. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation , 2003, Nature.
[16] Hui Zhao,et al. Disruption of the checkpoint kinase 1/cell division cycle 25A pathway abrogates ionizing radiation-induced S and G2 checkpoints , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[17] Michel C. Nussenzweig,et al. Genomic Instability in Mice Lacking Histone H2AX , 2002, Science.
[18] S M Bailey,et al. Strand-Specific Postreplicative Processing of Mammalian Telomeres , 2001, Science.
[19] M. Blasco,et al. Mammalian Ku86 protein prevents telomeric fusions independently of the length of TTAGGG repeats and the G‐strand overhang , 2000, EMBO reports.
[20] C. Allis,et al. Phosphorylation of linker histone H1 regulates gene expression in vivo by mimicking H1 removal. , 1999, Molecular cell.
[21] T. Myers,et al. Gadd45, a p53-Responsive Stress Protein, Modifies DNA Accessibility on Damaged Chromatin , 1999, Molecular and Cellular Biology.
[22] M. Gatei,et al. Chk1 complements the G2/M checkpoint defect and radiosensitivity of ataxia-telangiectasia cells , 1999, Oncogene.
[23] A. Carr,et al. Protein kinase mutants of human ATR increase sensitivity to UV and ionizing radiation and abrogate cell cycle checkpoint control. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[24] E. Rogakou,et al. DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139* , 1998, The Journal of Biological Chemistry.
[25] H. Tanke,et al. Telomeres in the mouse have large inter-chromosomal variations in the number of T2AG3 repeats. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[26] C. Allis,et al. Chromatin condensation: does histone H1 dephosphorylation play a role? , 1992, Trends in biochemical sciences.
[27] Kazuhide Takahashi,et al. Changes in Nuclease Sensitivity of Mammalian Cells after Irradiation with 60Co γ-rays , 1985 .
[28] Jiri Bartek,et al. ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks , 2006, Nature Cell Biology.
[29] Z. Herceg,et al. Histone acetylation by Trrap–Tip60 modulates loading of repair proteins and repair of DNA double-strand breaks , 2006, Nature Cell Biology.
[30] T. Misteli,et al. Hyperdynamic plasticity of chromatin proteins in pluripotent embryonic stem cells. , 2006, Developmental cell.
[31] S. Schreiber,et al. Overexpression of a kinase‐inactive ATR protein causes sensitivity to DNA‐damaging agents and defects in cell cycle checkpoints , 1998, The EMBO journal.
[32] I. Kaneko,et al. Changes in nuclease sensitivity of mammalian cells after irradiation with 60Co gamma-rays. , 1985, International journal of radiation biology and related studies in physics, chemistry, and medicine.