Plasmon resonant particles for biological detection.

Several recent advances in the optical observation, fabrication, and bioconjugation of nanometer-sized gold or silver colloids have produced a robust new class of label. These plasmon resonant particle (PRP) conjugates have several important advantages: they are ultra-bright, so the light scattered from the individual particles can be viewed using a simple optical microscope system with a white light illumination source; they do not photo-bleach; PRPs can be prepared that preferentially scatter light of a chosen color; and it is possible to prepare bioconjugated PRPs that are stable in solution. These properties, and the automation of PRP identification, discrimination, and counting, have enabled the development of ultrasensitive, multicolor, and multiplex applications in the life science field.

[1]  R. Sam Niedbala,et al.  Up-converting phosphor reporters for nucleic acid microarrays , 2001, Nature Biotechnology.

[2]  Kazunori Kataoka,et al.  Quantitative and Reversible Lectin-Induced Association of Gold Nanoparticles Modified with α-Lactosyl-ω-mercapto-poly(ethylene glycol) , 2001 .

[3]  George C. Schatz,et al.  Optical properties of metal nanoparticles and nanoparticle aggregates important in biosensors , 2000 .

[4]  J. Köhler,et al.  Chip-based optical detection of DNA hybridization by means of nanobead labeling. , 2000, Analytical chemistry.

[5]  R. V. Van Duyne,et al.  A nanoscale optical biosensor: sensitivity and selectivity of an approach based on the localized surface plasmon resonance spectroscopy of triangular silver nanoparticles. , 2002, Journal of the American Chemical Society.

[6]  Luca Quaroni,et al.  Preparation of Polymer-Coated Functionalized Silver Nanoparticles , 1999 .

[7]  David A. Schultz,et al.  Single-target molecule detection with nonbleaching multicolor optical immunolabels. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[8]  Chad A. Mirkin,et al.  One-Pot Colorimetric Differentiation of Polynucleotides with Single Base Imperfections Using Gold Nanoparticle Probes , 1998 .

[9]  Joseph T. Hupp,et al.  Gold Nanoparticle-Based Sensing of “Spectroscopically Silent” Heavy Metal Ions , 2001 .

[10]  Lin He,et al.  Particles for multiplexed analysis in solution: detection and identification of striped metallic particles using optical microscopy. , 2002, Analytical chemistry.

[11]  E. Purcell,et al.  Scattering and Absorption of Light by Nonspherical Dielectric Grains , 1973 .

[12]  M. Natan,et al.  Seeding of Colloidal Au Nanoparticle Solutions. 2. Improved Control of Particle Size and Shape , 2000 .

[13]  C. Mirkin,et al.  A gold nanoparticle/latex microsphere-based colorimetric oligonucleotide detection method , 2000 .

[14]  Richard K. Chang,et al.  Electrodynamic calculations of the surface-enhanced electric intensities on large Ag spheroids , 1983 .

[15]  M. Porter,et al.  Immunoassay readout method using extrinsic Raman labels adsorbed on immunogold colloids. , 1999, Analytical chemistry.

[16]  David R. Smith,et al.  Shape effects in plasmon resonance of individual colloidal silver nanoparticles , 2002 .

[17]  J. Yguerabide,et al.  Light-scattering submicroscopic particles as highly fluorescent analogs and their use as tracer labels in clinical and biological applications. , 1998, Analytical biochemistry.

[18]  R. G. Freeman,et al.  Submicrometer metallic barcodes. , 2001, Science.

[19]  C. Haynes,et al.  Nanosphere Lithography: A Versatile Nanofabrication Tool for Studies of Size-Dependent Nanoparticle Optics , 2001 .

[20]  Anthony G. Frutos,et al.  High-sensitivity detection of DNA hybridization on microarrays using resonance light scattering. , 2002, Analytical chemistry.

[21]  Sheldon Schultz,et al.  Further development of a scanned near-field optical microscope for magneto-optic Kerr imaging of magnetic domains with 10nm resolution , 1993, Photonics West - Lasers and Applications in Science and Engineering.

[22]  J. Yguerabide,et al.  Resonance light scattering particles as ultrasensitive labels for detection of analytes in a wide range of applications , 2001, Journal of cellular biochemistry. Supplement.

[23]  G. Mie.  Beiträge zur Optik trüber Medien, speziell kolloidaler Metallösungen , 1908 .

[24]  C. Mirkin,et al.  Multiple thiol-anchor capped DNA-gold nanoparticle conjugates. , 2002, Nucleic acids research.

[25]  Sheldon Schultz,et al.  Development toward magneto-optic Kerr scanned near-field optical microscope with 10-nm resolution , 1992, Photonics West - Lasers and Applications in Science and Engineering.

[26]  David L. Carroll,et al.  Synthesis and Characterization of Truncated Triangular Silver Nanoplates , 2002 .

[27]  G. Schatz,et al.  Discrete dipole approximation for calculating extinction and Raman intensities for small particles with arbitrary shapes , 1995 .

[28]  C. Mirkin,et al.  Nanoparticles with Raman spectroscopic fingerprints for DNA and RNA detection. , 2002, Science.

[29]  S. Nguyen,et al.  DNA-block copolymer conjugates. , 2001, Journal of the American Chemical Society.

[30]  Naomi J. Halas,et al.  GENERAL VECTOR BASIS FUNCTION SOLUTION OF MAXWELL'S EQUATIONS , 1997 .

[31]  Naomi J. Halas,et al.  Silver Nanoshells: Variations in Morphologies and Optical Properties , 2001 .

[32]  Naomi J. Halas,et al.  Nanoengineering of optical resonances , 1998 .

[33]  N. Jana,et al.  Preparation of Polystyrene- and Silica-Coated Gold Nanorods and Their Use as Templates for the Synthesis of Hollow Nanotubes , 2001 .

[34]  P. Englebienne.  Synthetic materials capable of reporting biomolecular recognition events by chromic transition , 1999 .

[35]  J. Storhoff,et al.  Selective colorimetric detection of polynucleotides based on the distance-dependent optical properties of gold nanoparticles. , 1997, Science.

[36]  David R. Smith,et al.  Composite Plasmon Resonant Nanowires , 2002 .

[37]  J. Baldeschwieler,et al.  Real-time detection of DNA hybridization and melting on oligonucleotide arrays by using optical wave guides. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[38]  C. Mirkin,et al.  DNA-modified core-shell Ag/Au nanoparticles. , 2001, Journal of the American Chemical Society.

[39]  Zeev Rosenzweig,et al.  Development of an aggregation-based immunoassay for anti-protein A using gold nanoparticles. , 2002, Analytical chemistry.

[40]  Steven R. Emory,et al.  Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering , 1997, Science.

[41]  Catherine J. Murphy,et al.  Seeding Growth for Size Control of 5−40 nm Diameter Gold Nanoparticles , 2001 .

[42]  Z. Kam,et al.  Absorption and Scattering of Light by Small Particles , 1998 .

[43]  S. L. Westcott,et al.  Infrared extinction properties of gold nanoshells , 1999 .

[44]  Wolfgang Fritzsche,et al.  Selective labeling of oligonucleotide monolayers by metallic nanobeads for fast optical readout of DNA-chips , 2001 .

[45]  J. Storhoff,et al.  Sequence-Dependent Stability of DNA-Modified Gold Nanoparticles , 2002 .

[46]  S. Schultz,et al.  A scanning near‐field optical microscope for the imaging of magnetic domains in reflection , 1996 .

[47]  S. Nie,et al.  Luminescent quantum dots for multiplexed biological detection and imaging. , 2002, Current opinion in biotechnology.

[48]  J. Yguerabide,et al.  Light-scattering submicroscopic particles as highly fluorescent analogs and their use as tracer labels in clinical and biological applications. , 1998, Analytical biochemistry.

[49]  R. Wannemacher,et al.  Preparation of Silver−Latex Composites , 2000 .

[50]  C. Mirkin,et al.  Homogeneous, Nanoparticle-Based Quantitative Colorimetric Detection of Oligonucleotides , 2000 .

[51]  D. Walt,et al.  Preparation of Polymer Coated Gold Nanoparticles by Surface-Confined Living Radical Polymerization at Ambient Temperature , 2002 .

[52]  David R. Smith,et al.  Dramatic localized electromagnetic enhancement in plasmon resonant nanowires , 2001 .

[53]  R. Dasari,et al.  Single Molecule Detection Using Surface-Enhanced Raman Scattering (SERS) , 1997 .

[54]  S. L. Westcott,et al.  Formation and Adsorption of Clusters of Gold Nanoparticles onto Functionalized Silica Nanoparticle Surfaces , 1998 .

[55]  C. Mirkin,et al.  Scanometric DNA array detection with nanoparticle probes. , 2000, Science.

[56]  C. Mirkin,et al.  Use of a steroid cyclic disulfide anchor in constructing gold nanoparticle-oligonucleotide conjugates. , 2000, Bioconjugate chemistry.

[57]  S. Oldenburg,et al.  Base pair mismatch recognition using plasmon resonant particle labels. , 2002, Analytical biochemistry.

[58]  C. Mirkin,et al.  Photoinduced Conversion of Silver Nanospheres to Nanoprisms , 2001, Science.

[59]  Catherine J. Murphy,et al.  Wet chemical synthesis of silver nanorods and nanowiresof controllable aspect ratio , 2001 .

[60]  Frank Caruso,et al.  Nanoengineering of particle surfaces. , 2001 .

[61]  C. Mirkin,et al.  Two-color labeling of oligonucleotide arrays via size-selective scattering of nanoparticle probes. , 2001, Journal of the American Chemical Society.

[62]  S. Takahashi,et al.  Using microparticle labeling and counting for attomole-level detection in heterogeneous immunoassay. , 1992, Analytical biochemistry.

[63]  T. Soukka,et al.  Europium nanoparticles and time-resolved fluorescence for ultrasensitive detection of prostate-specific antigen. , 2001, Clinical chemistry.

[64]  Catherine J. Murphy,et al.  Evidence for Seed-Mediated Nucleation in the Chemical Reduction of Gold Salts to Gold Nanoparticles , 2001 .

[65]  P Englebienne,et al.  Use of colloidal gold surface plasmon resonance peak shift to infer affinity constants from the interactions between protein antigens and antibodies specific for single or multiple epitopes. , 1998, The Analyst.

[66]  Naomi J. Halas,et al.  Enhanced thermal stability of silica-encapsulated metal nanoshells , 2001 .