Short burst oxygen therapy for relief of breathlessness in COPD

More evidence against the effect of short burst oxygen therapy, but doubts remain In this issue of Thorax Stevenson and Calverley1 provide more evidence for a lack of effect of short burst oxygen therapy in the relief of dyspnoea following exercise in patients with chronic obstructive pulmonary disease (COPD). This study follows other recent publications that appear to draw the same conclusion. Despite this mounting evidence, oxygen cylinders for “as needed” use are still frequently prescribed at great cost.2,3 Oxygen used in this way is often perceived as life saving by patients, but can this continuing practice of short burst oxygen use for COPD patients be justified in the light of the emerging evidence? Oxygen therapy for the management of chronic COPD comes in various forms. Long term oxygen therapy (LTOT) prescribing has an accepted evidence base and any patient considered for short burst treatment should first have undergone an assessment for LTOT. Ambulatory oxygen has been shown to have some beneficial effect in some patients researched in a number of studies that demonstrate some concordance. It is a continuing challenge to the respiratory establishment, however, that the form of oxygen most commonly prescribed in the UK lacks such an agreed evidence base. Short burst oxygen use for the palliation of dyspnoea is fairly widespread among patients with severe COPD.2 Anecdotally, it is beloved by them and often given at their request by respiratory specialists and general practitioners when other options have been exhausted. When it is given there is some evidence that it is used inconsistently4—either before or after exercise—and that the delivery mode is non-standardised with both face masks and nasal cannulae being used with flow rates set usually at 2 or 4 l/min, but often left to the discretion of the …

[1]  P. Calverley,et al.  Effect of oxygen on recovery from maximal exercise in patients with chronic obstructive pulmonary disease , 2004, Thorax.

[2]  D. Forman,et al.  Delays in managing lung cancer. , 2004, Thorax.

[3]  P. Young,et al.  Shortburst oxygen immediately before and after exercise is ineffective in nonhypoxic COPD patients , 2003, European Respiratory Journal.

[4]  R. Garrod,et al.  Oxygen supplementation before or after submaximal exercise in patients with chronic obstructive pulmonary disease , 2003, Thorax.

[5]  P. Young,et al.  Ambulatory oxygen improves quality of life of COPD patients: a randomised controlled study , 2002, European Respiratory Journal.

[6]  P. Corris,et al.  A pragmatic assessment of the placement of oxygen when given for exercise induced dyspnoea , 2000, Thorax.

[7]  C. Cooper,et al.  Treadmill exercise duration and dyspnea recovery time in chronic obstructive pulmonary disease: effects of oxygen breathing and repeated testing. , 1998, Respiratory medicine.

[8]  J C Yernault,et al.  Optimal assessment and management of chronic obstructive pulmonary disease (COPD). The European Respiratory Society Task Force. , 1995, The European respiratory journal.

[9]  J. Wedzicha,et al.  Domiciliary oxygen cylinders: indications, prescription and usage. , 1994, Respiratory medicine.

[10]  P. Calverley,et al.  Does cold air affect exercise capacity and dyspnea in stable chronic obstructive pulmonary disease? , 1993, Chest.

[11]  N. Dean,et al.  Oxygen may improve dyspnea and endurance in patients with chronic obstructive pulmonary disease and only mild hypoxemia. , 1992, The American review of respiratory disease.

[12]  S. Chinn,et al.  Portable liquid oxygen and exercise ability in severe respiratory disability. , 1992, Thorax.

[13]  P. Corris,et al.  Symptomatic benefit of supplemental oxygen in hypoxemic patients with chronic lung disease. , 1991, The American review of respiratory disease.

[14]  D. Geddes,et al.  Supplemental oxygen and exercise ability in chronic obstructive airways disease. , 1988, Thorax.

[15]  N. Saunders,et al.  Effects of breathing supplemental oxygen before progressive exercise in patients with chronic obstructive lung disease. , 1988, Thorax.

[16]  Phillips Yy,et al.  Standards for the diagnosis and care of patients with chronic obstructive pulmonary disease (COPD) and asthma. This official statement of the American Thoracic Society was adopted by the ATS Board of Directors, November 1986. , 1987, The American review of respiratory disease.

[17]  T. Evans,et al.  Short burst oxygen treatment for breathlessness in chronic obstructive airways disease. , 1986, Thorax.

[18]  A. Woodcock,et al.  OXYGEN RELIEVES BREATHLESSNESS IN "PINK PUFFERS" , 1981, The Lancet.