论文信息 - Synthesis and biological evaluation of thiazole derivatives as novel USP7 inhibitors. - 字舞流文

Synthesis and biological evaluation of thiazole derivatives as novel USP7 inhibitors.

W. Gu | Chang Xu | Hongbin Sun | Xiaoan Wen | Caiping Chen | Jinzheng Wang | Chao Chen | Jiemei Song

[1] A. Califano,et al. HAUSP deubiquitinated and stabilizes N-Myc in neuroblastoma , 2016, Nature Medicine.

[2] P. Cao,et al. Selective Dual Inhibitors of the Cancer-Related Deubiquitylating Proteases USP7 and USP47. , 2012, ACS medicinal chemistry letters.

[3] Parantu K. Shah,et al. A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. , 2012, Cancer cell.

[4] V. Battaglia,et al. Discovery of specific inhibitors of human USP7/HAUSP deubiquitinating enzyme. , 2012, Chemistry & biology.

[5] G. Dianov,et al. Activity-based chemical proteomics accelerates inhibitor development for deubiquitylating enzymes. , 2011, Chemistry & biology.

[6] C. Brown,et al. Mechanism-specific signatures for small-molecule p53 activators , 2011, Cell cycle.

[7] J. Rain,et al. Small-molecule inhibitor of USP7/HAUSP ubiquitin protease stabilizes and activates p53 in cells , 2009, Molecular Cancer Therapeutics.

[8] Wei Gu,et al. p53 ubiquitination: Mdm2 and beyond. , 2006, Molecular cell.

[9] Muyang Li,et al. A dynamic role of HAUSP in the p53-Mdm2 pathway. , 2004, Molecular cell.

[10] J. Qin,et al. Deubiquitination of p53 by HAUSP is an important pathway for p53 stabilization , 2002, Nature.