Bioactive Potential of Marine Macroalgae from the Central Red Sea (Saudi Arabia) Assessed by High-Throughput Imaging-Based Phenotypic Profiling
暂无分享,去创建一个
[1] C. Voolstra,et al. High-resolution phenotypic profiling of natural products-induced effects on the single-cell level , 2017, Scientific Reports.
[2] Anne E Carpenter,et al. Applications in image-based profiling of perturbations. , 2016, Current opinion in biotechnology.
[3] Anne E Carpenter,et al. Cell Painting, a high-content image-based assay for morphological profiling using multiplexed fluorescent dyes , 2016, Nature Protocols.
[4] Roger G Linington,et al. Integration of high-content screening and untargeted metabolomics for comprehensive functional annotation of natural product libraries , 2015, Proceedings of the National Academy of Sciences.
[5] A. Harvey,et al. The re-emergence of natural products for drug discovery in the genomics era , 2015, Nature Reviews Drug Discovery.
[6] M. Saha,et al. Large Scale Patterns of Antimicrofouling Defenses in the Hard Coral Pocillopora verrucosa in an Environmental Gradient along the Saudi Arabian Coast of the Red Sea , 2014, PloS one.
[7] C. Wild,et al. Aqueous Extracts of the Marine Brown Alga Lobophora variegata Inhibit HIV-1 Infection at the Level of Virus Entry into Cells , 2014, PloS one.
[8] C. Voolstra,et al. Spatio-Temporal Analyses of Symbiodinium Physiology of the Coral Pocillopora verrucosa along Large-Scale Nutrient and Temperature Gradients in the Red Sea , 2014, PloS one.
[9] T. Bradshaw,et al. Novel antitumour indole alkaloid, Jerantinine A, evokes potent G2/M cell cycle arrest targeting microtubules , 2014, Investigational New Drugs.
[10] S. Sivasubramanian,et al. Induction of ROS-dependent mitochondria-mediated intrinsic apoptosis in MDA-MB-231 cells by glycoprotein from Codium decorticatum. , 2014, Journal of agricultural and food chemistry.
[11] H. Gaspar,et al. Marketed Marine Natural Products in the Pharmaceutical and Cosmeceutical Industries: Tips for Success , 2014, Marine drugs.
[12] M. Berumen,et al. First biological measurements of deep-sea corals from the Red Sea , 2013, Scientific Reports.
[13] Wun-Jae Kim,et al. Decitabine, a DNA methyltransferases inhibitor, induces cell cycle arrest at G2/M phase through p53-independent pathway in human cancer cells. , 2013, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[14] Joshua M. Stuart,et al. "Function-first" lead discovery: mode of action profiling of natural product libraries using image-based screening. , 2013, Chemistry & biology.
[15] J. Hyun,et al. Cytotoxic Effect of Clerosterol Isolated from Codium fragile on A2058 Human Melanoma Cells , 2013, Marine drugs.
[16] Franco Moritz,et al. Molecular cartography in acute Chlamydia pneumoniae infections—a non-targeted metabolomics approach , 2013, Analytical and Bioanalytical Chemistry.
[17] P. Schmitt‐Kopplin,et al. Quorum Sensing Inhibition by Asparagopsis taxiformis, a Marine Macro Alga: Separation of the Compound that Interrupts Bacterial Communication , 2013, Marine drugs.
[18] Y. Yoo,et al. Taxol-induced growth arrest and apoptosis is associated with the upregulation of the Cdk inhibitor, p21WAF1/CIP1, in human breast cancer cells. , 2012, Oncology reports.
[19] Y. Yoo,et al. 7,8-dihydroxyflavone induces G1 arrest of the cell cycle in U937 human monocytic leukemia cells via induction of the Cdk inhibitor p27 and downregulation of pRB phosphorylation. , 2012, Oncology reports.
[20] D. Schols,et al. Algal Lectins as Potential HIV Microbicide Candidates , 2012, Marine drugs.
[21] Bradley S Moore,et al. Lessons from the past and charting the future of marine natural products drug discovery and chemical biology. , 2012, Chemistry & biology.
[22] J. Serôdio,et al. Trends in the Discovery of New Marine Natural Products from Invertebrates over the Last Two Decades – Where and What Are We Bioprospecting? , 2012, PloS one.
[23] M. Irhimeh,et al. Dietary algae and HIV/AIDS: proof of concept clinical data , 2011, Journal of Applied Phycology.
[24] L. Mhadhebi,et al. Antioxidant, anti-inflammatory, and antiproliferative activities of organic fractions from the Mediterranean brown seaweed Cystoseira sedoides. , 2011, Canadian journal of physiology and pharmacology.
[25] L. Altucci,et al. Total synthesis of the proposed structures of the DNA methyl transferase inhibitors peyssonenynes, and structural revision of peyssonenyne B. , 2011, Organic & biomolecular chemistry.
[26] N. Hertkorn,et al. Kendrick-Analogous Network Visualisation of Ion Cyclotron Resonance Fourier Transform Mass Spectra: Improved Options for the Assignment of Elemental Compositions and the Classification of Organic Molecular Complexity , 2011, European journal of mass spectrometry.
[27] A. Lalvani,et al. Evaluation of Turkish seaweeds for antiprotozoal, antimycobacterial and cytotoxic activities , 2011, Phytotherapy research : PTR.
[28] Hiroaki Sasaki,et al. Cell-morphology profiling of a natural product library identifies bisebromoamide and miuraenamide A as actin filament stabilizers. , 2011, ACS chemical biology.
[29] Jonathan Low,et al. A Robust High-Content Imaging Approach for Probing the Mechanism of Action and Phenotypic Outcomes of Cell-Cycle Modulators , 2011, Molecular Cancer Therapeutics.
[30] C. Fairchild,et al. Structure and biological evaluation of novel cytotoxic sterol glycosides from the marine red alga Peyssonnelia sp. , 2010, Bioorganic & medicinal chemistry.
[31] M. Guiry,et al. Antimycobacterial, antiprotozoal and cytotoxic potential of twenty‐one brown algae (phaeophyceae) from British and Irish waters , 2010, Phytotherapy research : PTR.
[32] A. Lalvani,et al. Antiprotozoal, antimycobacterial and cytotoxic potential of some british green algae , 2010, Phytotherapy research : PTR.
[33] H. Cho,et al. Piceatannol, a natural stilbene from grapes, induces G1 cell cycle arrest in androgen-insensitive DU145 human prostate cancer cells via the inhibition of CDK activity. , 2009, Cancer letters.
[34] Guoqiang Chen,et al. Inhibition of DNA methyltransferase induces G2 cell cycle arrest and apoptosis in human colorectal cancer cells via inhibition of JAK2/STAT3/STAT5 signalling , 2009, Journal of cellular and molecular medicine.
[35] John A. Tallarico,et al. Multi-parameter phenotypic profiling: using cellular effects to characterize small-molecule compounds , 2009, Nature Reviews Drug Discovery.
[36] P. Sylvester,et al. Combined Treatment of γ-Tocotrienol with Statins Induce Mammary Tumor Cell Cycle Arrest in G1 , 2009, Experimental biology and medicine.
[37] P. Schmitt‐Kopplin,et al. Natural organic matter and the event horizon of mass spectrometry. , 2008, Analytical chemistry.
[38] H. Rocha,et al. Sulfated galactofucan from Lobophora variegata: Anticoagulant and anti-inflammatory properties , 2008, Biochemistry (Moscow).
[39] F. Karadeniz,et al. Anti-HIV-1 activity of phloroglucinol derivative, 6,6'-bieckol, from Ecklonia cava. , 2008, Bioorganic & medicinal chemistry.
[40] D. Robledo,et al. Antileishmanial properties of tropical marine algae extracts. , 2008, Fitoterapia.
[41] Mary Kay Harper,et al. Fractionated Marine Invertebrate Extract Libraries for Drug Discovery , 2008, Molecules.
[42] H. Aoyama,et al. Inhibition of reverse transcriptase activity of HIV by polysaccharides of brown algae. , 2008, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
[43] T. Dittmar,et al. A simple and efficient method for the solid‐phase extraction of dissolved organic matter (SPE‐DOM) from seawater , 2008 .
[44] M. K. Harper,et al. Marine Natural Product Libraries for High-Throughput Screening and Rapid Drug Discovery , 2008, Journal of natural products.
[45] E. Krausz,et al. Cell-based high-content screening of small-molecule libraries. , 2007, Current opinion in chemical biology.
[46] H. Liu,et al. Quercetin induces cell cycle G1 arrest through elevating Cdk inhibitors p21 and p27 in human hepatoma cell line (HepG2). , 2007, Methods and findings in experimental and clinical pharmacology.
[47] A. Fourest-Lieuvin,et al. Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1. , 2005, Molecular biology of the cell.
[48] Barry R O'Keefe,et al. Isolation and Characterization of Griffithsin, a Novel HIV-inactivating Protein, from the Red Alga Griffithsia sp.* , 2005, Journal of Biological Chemistry.
[49] W. Gerwick,et al. Peyssonenynes a and B, novel enediyne oxylipins with DNA methyl transferase inhibitory activity from the red marine alga peyssonneliacaulifera. , 2004, Journal of natural products.
[50] P. Sawangwong,et al. Drugs and Cosmetics from the Sea , 2004, Marine Drugs.
[51] S. Kim,et al. Inhibition of HIV-1 reverse transcriptase and protease by phlorotannins from the brown alga Ecklonia cava. , 2004, Biological & pharmaceutical bulletin.
[52] J. Hébert,et al. Algae -- a poor man's HAART? , 2004, Medical hypotheses.
[53] Jen-kun Lin,et al. Tangeretin induces cell-cycle G1 arrest through inhibiting cyclin-dependent kinases 2 and 4 activities as well as elevating Cdk inhibitors p21 and p27 in human colorectal carcinoma cells. , 2002, Carcinogenesis.
[54] E. Clercq,et al. Sulfated polysaccharides extracted from sea algae as potential antiviral drugs. , 1997, General pharmacology.
[55] Adem Güner,et al. Antimicrobial and antioxidant activities with acute toxicity, cytotoxicity and mutagenicity of Cystoseira compressa (Esper) Gerloff & Nizamuddin from the coast of Urla (Izmir, Turkey) , 2013, Cytotechnology.
[56] Se-Kwon Kim,et al. Anti-HIV activity of extracts and compounds from marine algae. , 2011, Advances in food and nutrition research.
[57] Se-kwon Kim,et al. Anticancer compounds from marine macroalgae and their application as medicinal foods. , 2011, Advances in food and nutrition research.
[58] S. Nabavi,et al. Cytotoxic activity of some marine brown algae against cancer cell lines. , 2010, Biological research.
[59] John A. Tallarico,et al. Integrating high-content screening and ligand-target prediction to identify mechanism of action. , 2008, Nature chemical biology.
[60] T. Hoye,et al. Cytotoxic Hydroazulene Diterpenes from the Brown Alga Cystoseira myrica , 2003, Zeitschrift fur Naturforschung. C, Journal of biosciences.
[61] D. Faulkner. Marine natural products. , 2000, Natural product reports.