A new series of flavones, thioflavones, and flavanones as selective monoamine oxidase-B inhibitors.

[1]  D. Secci,et al.  Chalcones: a valid scaffold for monoamine oxidases inhibitors. , 2009, Journal of medicinal chemistry.

[2]  Stefano Alcaro,et al.  Synthesis, molecular modeling, and selective inhibitory activity against human monoamine oxidases of 3-carboxamido-7-substituted coumarins. , 2009, Journal of medicinal chemistry.

[3]  B. Bloem,et al.  Postural instability in Parkinson’s disease: the adrenergic hypothesis and the locus coeruleus , 2009, Expert review of neurotherapeutics.

[4]  F. Orallo Trans-resveratrol: a magical elixir of eternal youth? , 2008, Current medicinal chemistry.

[5]  R. Cirilli,et al.  High-performance liquid chromatography separation of enantiomers of flavanone and 2'-hydroxychalcone under reversed-phase conditions. , 2008, Journal of chromatography. A.

[6]  S. Shankar,et al.  Green tea polyphenols: biology and therapeutic implications in cancer. , 2007, Frontiers in bioscience : a journal and virtual library.

[7]  H. Fang,et al.  Recent advance in the research of flavonoids as anticancer agents. , 2007, Mini reviews in medicinal chemistry.

[8]  Stefano Alcaro,et al.  Quercetin as the active principle of Hypericum hircinum exerts a selective inhibitory activity against MAO-A: extraction, biological analysis, and computational study. , 2006, Journal of natural products.

[9]  Goutam Gorai Progress in the Research on Naturally Occurring Flavones and Flavonols: An Overview , 2006 .

[10]  L. Roguin,et al.  Antitumor activity of some natural flavonoids and synthetic derivatives on various human and murine cancer cell lines. , 2006, Bioorganic & medicinal chemistry.

[11]  Keith F. Tipton,et al.  The therapeutic potential of monoamine oxidase inhibitors , 2006, Nature Reviews Neuroscience.

[12]  Claire Henchcliffe,et al.  Recent advances in Parkinson’s disease therapy: use of monoamine oxidase inhibitors , 2005, Expert review of neurotherapeutics.

[13]  A. Scalbert,et al.  Polyphenols and prevention of cardiovascular diseases , 2005, Current opinion in lipidology.

[14]  K. Tipton,et al.  Monoamine oxidases: certainties and uncertainties. , 2004, Current medicinal chemistry.

[15]  A. Mattevi,et al.  Structure and mechanism of monoamine oxidase. , 2004, Current medicinal chemistry.

[16]  A. Mattevi,et al.  Crystal structure of human monoamine oxidase B, a drug target enzyme monotopically inserted into the mitochondrial outer membrane , 2004, FEBS letters.

[17]  S. Kulkarni,et al.  Quercetin Potentiates L-Dopa Reversal of Drug-Induced Catalepsy in Rats: Possible COMT/MAO Inhibition , 2003, Pharmacology.

[18]  V. Muñoz,et al.  Natural products as trypanocidal, antileishmanial and antimalarial drugs. , 2002, Current topics in medicinal chemistry.

[19]  A. Paladini,et al.  GABA(A)-receptor ligands of flavonoid structure. , 2002, Current topics in medicinal chemistry.

[20]  K. Shin,et al.  Synthesis of flavonoids and their effects on aldose reductase and sorbitol accumulation in streptozotocin‐induced diabetic rat tissues , 2001, The Journal of pharmacy and pharmacology.

[21]  R. Friesner,et al.  Evaluation and Reparametrization of the OPLS-AA Force Field for Proteins via Comparison with Accurate Quantum Chemical Calculations on Peptides† , 2001 .

[22]  K. Grohmann,et al.  Biological properties of citrus flavonoids pertaining to cancer and inflammation. , 2001, Current medicinal chemistry.

[23]  E. Middleton,et al.  The effects of plant flavonoids on mammalian cells: implications for inflammation, heart disease, and cancer. , 2000, Pharmacological reviews.

[24]  I. Yoo,et al.  Phenolics with Inhibitory Activity on Mouse Brain Monoamine Oxidase (MAO) from Whole Parts of Artemisia vulgaris L (Mugwort) , 2000 .

[25]  G. V. Paolini,et al.  Empirical scoring functions: I. The development of a fast empirical scoring function to estimate the binding affinity of ligands in receptor complexes , 1997, J. Comput. Aided Mol. Des..

[26]  K. Gomi,et al.  Novel 5-aminoflavone derivatives as specific antitumor agents in breast cancer. , 1996, Journal of medicinal chemistry.

[27]  M. Boyd,et al.  Centaureidin, a cytotoxic flavone from Polymnia fruticosa, inhibits tubulin polymerization , 1993 .

[28]  P. Riederer,et al.  The molecular pharmacology of L-deprenyl. , 1992, European journal of pharmacology.

[29]  M. Cushman,et al.  Cytotoxicities of some flavonoid analogues. , 1991, Journal of natural products.

[30]  G. Chang,et al.  Macromodel—an integrated software system for modeling organic and bioorganic molecules using molecular mechanics , 1990 .

[31]  T. Hayashi,et al.  A cytotoxic flavone from Scoparia dulcis L. , 1988, Chemical & pharmaceutical bulletin.

[32]  J. Schildkraut,et al.  The catecholamine hypothesis of affective disorders: a review of supporting evidence. , 1965, The American journal of psychiatry.

[33]  Myung-Koo Lee,et al.  Monoamine oxidase inhibitory components fromCayratia japonica , 2007, Archives of pharmacal research.

[34]  W. Delano The PyMOL Molecular Graphics System , 2002 .

[35]  N. O'Brien,et al.  Dietary flavonols: chemistry, food content, and metabolism. , 2002, Nutrition.

[36]  J. Harborne,et al.  The handbook of natural flavonoids. Volume 1 and Volume 2. , 1999 .

[37]  A. Lévai, AN EFFICIENT PROCEDURE FOR THE PREPARATION OF 4-THIOFLAVONES BY THE REACTION OF FLAVONES WITH LAWESSON'S REAGENT , 1999 .

[38]  R. Duggleby,et al.  Kinetics of slow and tight-binding inhibitors. , 1995, Methods in enzymology.

[39]  T. Fukai,et al.  Revised structures of albanins D and E, geranylated flavones from morus alba , 1991 .

[40]  W. C. Still,et al.  A rapid approximation to the solvent accessible surface areas of atoms , 1988 .

[41]  H. Berman,et al.  Electronic Reprint Biological Crystallography the Protein Data Bank Biological Crystallography the Protein Data Bank , 2022 .