Digital Image Cytometry for 3D Nuclear Feature Analysis in Volumetric Data

A method for prevention of unauthorized copying from information recording media, such as diskettes, comprising the steps of altering the information storage characteristics of the information recording media at selectable locations thereon, analyzing the information recording media after the alteration to provide a storable indication of the precise locations of the alteration, and recording onto the altered recording media information the copying of which is to be resisted, the information thus recorded including said storable indication of the precise locations of the alteration and instructions to user apparatus to verify the altered status of the recording media at said precise locations. A protected recording medium is also disclosed and claimed.