Acidic pH enhances the invasive behavior of human melanoma cells

[1]  Bonnie F. Sloane,et al.  Pericellular pH affects distribution and secretion of cathepsin B in malignant cells. , 1994, Cancer research.

[2]  Michael S. Pepper,et al.  Membrane proteases in focus , 1994, Nature.

[3]  R. Gillies,et al.  31P-MRS measurements of extracellular pH of tumors using 3-aminopropylphosphonate. , 1994, The American journal of physiology.

[4]  S. Morris,et al.  Simultaneous imaging of intracellular [Ca2+] and pH in single MDCK and glomerular epithelial cells. , 1993, The American journal of physiology.

[5]  A. Ikai,et al.  Isolation and characterization of a novel serine proteinase complexed with alpha 2-macroglobulin from porcine gastric mucosa. , 1993, The Journal of biological chemistry.

[6]  L. Liotta,et al.  Type IV collagen stimulates an increase in intracellular calcium. Potential role in tumor cell motility. , 1992, The Journal of biological chemistry.

[7]  M. Baker,et al.  Occupancy of the cancer cell urokinase receptor (uPAR): effects of acid elution and exogenous uPA on cell surface urokinase (uPA). , 1992, Biochimica et biophysica acta.

[8]  L. Matrisian.  The matrix‐degrading metalloproteinases , 1992, Journal of neuro-oncology.

[9]  Y. Kato,et al.  Induction of 103-kDa gelatinase/type IV collagenase by acidic culture conditions in mouse metastatic melanoma cell lines. , 1992, The Journal of biological chemistry.

[10]  M. Duffy.  The role of proteolytic enzymes in cancer invasion and metastasis , 1992, Clinical & Experimental Metastasis.

[11]  M. Hendrix,et al.  Coexpression of vimentin and keratins by human melanoma tumor cells: correlation with invasive and metastatic potential. , 1992, Journal of the National Cancer Institute.

[12]  R. Golouh,et al.  Stefins and lysosomal cathepsins B, L and D in human breast carcinoma , 1992, International journal of cancer.

[13]  D. Belin,et al.  The plasminogen activator/plasmin system. , 1991, The Journal of clinical investigation.

[14]  R. Hill,et al.  Glucose starvation and acidosis: effect on experimental metastatic potential, DNA content and MTX resistance of murine tumour cells. , 1991, British Journal of Cancer.

[15]  J. Griffiths.  Are cancer cells acidic? , 1991, British Journal of Cancer.

[16]  J. Woessner,et al.  Matrix metalloproteinases and their inhibitors in connective tissue remodeling , 1991, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[17]  D. Loskutoff,et al.  Platelets stimulate endothelial cells to synthesize type 1 plasminogen activator inhibitor. Evaluation of the role of transforming growth factor beta. , 1991, Blood.

[18]  R. Gillies,et al.  Simultaneous measurement of intracellular pH and Ca2+ using the fluorescence of SNARF-1 and fura-2. , 1991, The American journal of physiology.

[19]  J. Milne,et al.  A Ca2+ transport system associated with the plasma membrane of Dictyostelium discoideum is activated by different chemoattractant receptors , 1991, The Journal of cell biology.

[20]  W. Stetler-Stevenson.  Type IV collagenases in tumor invasion and metastasis , 1990, Cancer and Metastasis Reviews.

[21]  J R Griffiths,et al.  The energy metabolism of RIF-1 tumours following hydralazine. , 1990, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[22]  R. Gillies,et al.  Tumorigenic 3T3 cells maintain an alkaline intracellular pH under physiological conditions. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[23]  F. Lattanzio.  The effects of pH and temperature on fluorescent calcium indicators as determined with Chelex-100 and EDTA buffer systems. , 1990, Biochemical and biophysical research communications.

[24]  M. Mareel,et al.  The invasive phenotypes , 1990, Cancer and Metastasis Reviews.

[25]  F. Miller,et al.  Cellular interactions in metastasis , 1990, Cancer and Metastasis Reviews.

[26]  M. Aardema,et al.  Multistage neoplastic transformation of Syrian hamster embryo cells cultured at pH 6.70. , 1990, Cancer research.

[27]  R. Morimoto,et al.  In vitro activation of heat shock transcription factor DNA-binding by calcium and biochemical conditions that affect protein conformation. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[28]  E. W. Khandjian.  Acidic extracellular environment induces only a subset of heat-shock proteins in primary mouse kidney cell cultures. , 1990, Biochemistry and cell biology = Biochimie et biologie cellulaire.

[29]  F. Maxfield,et al.  Transient increases in cytosolic free calcium appear to be required for the migration of adherent human neutrophils [published erratum appears in J Cell Biol 1990 Mar;110(3):861] , 1990, The Journal of cell biology.

[30]  P. Okunieff,et al.  Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. , 1989, Cancer research.

[31]  T. Stossel,et al.  From signal to pseudopod. How cells control cytoplasmic actin assembly. , 1989, The Journal of biological chemistry.

[32]  C. Lechene,et al.  Effect of cell spreading on cytoplasmic pH in normal and transformed fibroblasts. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[33]  R. Kerbel,et al.  Possible involvement of Ca2+ mobilization and protein kinase C activation in the induction of spontaneous metastasis by mouse mammary adenocarcinoma cells. , 1989, Cancer research.

[34]  R. Gillies,et al.  Sphingosine inhibits phorbol 12‐myristate 13‐acetate‐, but not serum‐induced, activation of Na+/H+ exchange in mammalian cells , 1989, Journal of cellular physiology.

[35]  R. Jain,et al.  Blood flow and venous pH of tissue-isolated Walker 256 carcinoma during hyperglycemia. , 1988, Cancer research.

[36]  M. Hendrix,et al.  A simple quantitative assay for studying the invasive potential of high and low human metastatic variants. , 1987, Cancer letters.

[37]  P. Herrlich,et al.  12-O-tetradecanoyl-phorbol-13-acetate induction of the human collagenase gene is mediated by an inducible enhancer element located in the 5'-flanking region , 1987, Molecular and cellular biology.

[38]  Z. Werb,et al.  Coordinate regulation of stromelysin and collagenase genes determined with cDNA probes. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[39]  R. Gillies,et al.  Determination of cell number in monolayer cultures. , 1986, Analytical biochemistry.

[40]  P. Waterhouse,et al.  A growth-responsive gene (16C8) in normal mouse fibroblasts homologous to a human collagenase inhibitor with erythroid-potentiating activity: evidence for inducible and constitutive transcripts. , 1986, Nucleic acids research.

[41]  G. O'Connor,et al.  Half-life of synovial cell collagenase mRNA is modulated by phorbol myristate acetate but not by all-trans-retinoic acid or dexamethasone. , 1986, Biochemistry.

[42]  E. Rozengurt.  Early signals in the mitogenic response. , 1986, Science.

[43]  H. Rochefort,et al.  The 52-kDa estrogen-induced protein secreted by MCF7 cells is a lysosomal acidic protease. , 1986, Biochemical and biophysical research communications.

[44]  L. Vicentini,et al.  Inositol phosphates turnover, cytosolic Ca++ and pH: putative signals for the control of cell growth. , 1986, Life sciences.

[45]  D Soifer,et al.  Factors Regulating the Presence of Microtubules in Cells , 1986, Annals of the New York Academy of Sciences.

[46]  Y. Nagamine,et al.  Induction and desensitization of plasminogen activator gene expression by tumor promoters. , 1985, The Journal of biological chemistry.

[47]  Z. Werb,et al.  Biosynthesis of tissue inhibitor of metalloproteinases by human fibroblasts in culture. Stimulation by 12-O-tetradecanoylphorbol 13-acetate and interleukin 1 in parallel with collagenase. , 1985, The Journal of biological chemistry.

[48]  Z. Fuks,et al.  Characterization of an extracellular matrix-degrading protease derived from a highly metastatic tumor cell line. , 1985, European journal of cancer & clinical oncology.

[49]  John P. Moore,et al.  A common sequence of calcium and pH signals in the mitogenic stimulation of eukaryotic cells , 1985, Nature.

[50]  J. Haveman,et al.  The relevance of tumour pH to the treatment of malignant disease. , 1984, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[51]  F. Meyskens,et al.  Dexamethasone, prostaglandin A, and retinoic acid modulation of murine and human melanoma cells grown in soft agar. , 1983, Journal of the National Cancer Institute.

[52]  L. Liotta,et al.  Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma. , 1982, Biochemistry.

[53]  Franz Wind,et al.  Über den Stoffwechsel von Tumoren im Körper , 1926, Klinische Wochenschrift.

[54]  K. Tryggvason,et al.  Type IV collagenases in invasive tumors , 2005, Breast Cancer Research and Treatment.

[55]  P. Walker,et al.  Calcium, cyclic AMP and protein kinase C — partners in mitogenesis , 2004, Cancer and Metastasis Reviews.

[56]  R. E. Seftor.  Electrophoretic analysis of proteins associated with tumor cell invasion , 1994, Electrophoresis.

[57]  G. Nicolson.  Paracrine/autocrine growth mechanisms in tumor metastasis. , 1992, Oncology research.

[58]  Nicolson Gl.  Paracrine/autocrine growth mechanisms in tumor metastasis. , 1992 .

[59]  S. Aliño,et al.  Correlation between secretion pattern and metastatic potential from drug-treated 3LL tumor cell line. , 1991, Cellular and molecular biology.

[60]  I. Fidler,et al.  Cancer metastasis. , 1991, British medical bulletin.

[61]  L. Matrisian,et al.  Metalloproteinases and their inhibitors in matrix remodeling. , 1990, Trends in genetics : TIG.

[62]  S. Barsky,et al.  Tumor promoter-induced membrane-bound protein kinase C regulates hematogenous metastasis. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[63]  M. Berridge,et al.  Inositol trisphosphate and diacylglycerol: two interacting second messengers. , 1987, Annual review of biochemistry.

[64]  K. Nabeshima,et al.  Partial purification and characterization of serum protease from tumor-bearing rats which cleaves type IV collagen. , 1986, Invasion & metastasis.

[65]  W. Moolenaar.  Effects of growth factors on intracellular pH regulation. , 1986, Annual review of physiology.

[66]  K. Takenaga,et al.  Effects of 12-O-tetradecanoylphorbol-13-acetate on adhesiveness and lung-colonizing ability of Lewis lung carcinoma cells. , 1986, Cancer research.

[67]  D. Soifer.  Dynamic aspects of microtubule biology. , 1986, Annals of the New York Academy of Sciences.

[68]  O. Warburg,et al.  Über den Stoffwechsel der Tumoren : Arbeiten aus dem Kaiser Wilhelm Institut für Biologie, Berlin- Dahlem , 1926 .