3',4'-Dimethoxy Quercetin, a Flavonol Compound Isolated from Kalanchoe pinnata

Article history: Received on: 19/12/2012 Revised on: 09/01/2013 Accepted on: 19/01/2013 Available online: 28/01/2013 From methanol extract of Kalanchoe pinnata (Lam.) Pers. leaves, a flavonol compound has been isolated. Fractionation of the methanol extract with ethyl acetate, followed by ethyl acetate fraction purification using column chromatography method with ethyl acetate : n-hexane as mobile phase gave a yellow crystal compound (A). Further analysis using 1Dand 2D-nuclear magnetic resonance (NMR), confirmed with mass spectrometer (LC-MS), compound A identified as 3’,4’-dimethoxy quercetin.

[1]  Mohammad Pravez,et al.  Anti-inflammatory and analgesic potential of a novel steroidal derivative from Bryophyllum pinnatum. , 2012, Fitoterapia.

[2]  S. El-Ahmady,et al.  Phenolics from Kalanchoe marmorata Baker, Family Crassulaceae , 2011 .

[3]  B. S. Nayak,et al.  Wound healing potential of ethanolic extract of Kalanchoe pinnata Lam. leaf--a preliminary study. , 2010, Indian journal of experimental biology.

[4]  B. Rossi-Bergmann,et al.  Immunomodulatory pretreatment with Kalanchoe pinnata extract and its quercitrin flavonoid effectively protects mice against fatal anaphylactic shock. , 2008, International immunopharmacology.

[5]  P. Kuo,et al.  Cytotoxic principles and α-pyrone ring-opening derivatives of bufadienolides from Kalanchoe hybrida , 2008 .

[6]  K. Lee,et al.  Kalanchosides A-C, new cytotoxic bufadienolides from the aerial parts of Kalanchoe gracilis. , 2006, Organic letters.

[7]  B. Rossi-Bergmann,et al.  The antileishmanial activity assessment of unusual flavonoids from Kalanchoe pinnata. , 2006, Phytochemistry.

[8]  D. Njamen,et al.  Analgesic and anticonvulsant effects of extracts from the leaves of Kalanchoe crenata (Andrews) Haworth (Crassulaceae). , 2006, Journal of ethnopharmacology.

[9]  V. Dixit,et al.  Hepatoprotective activity of leaves of Kalanchoe pinnata Pers. , 2003, Journal of ethnopharmacology.

[10]  J. Ojewole P-2: Antihypertensive properties of Bryophyllum pinnatum {(Lam) Oken} leaf extracts , 2002 .

[11]  K. Akiyama,et al.  Insecticidal compounds from Kalanchoe daigremontiana x tubiflora. , 2001, Phytochemistry.

[12]  K. Akiyama,et al.  Anti-tumor Promoting Activity of Bufadienolides from Kalanchoe pinnata and K. daigremontiana × butiflora , 2001, Bioscience, biotechnology, and biochemistry.

[13]  D. Akinpelu Antimicrobial activity of Bryophyllum pinnatum leaves. , 2000, Fitoterapia.

[14]  K. Akiyama,et al.  New Insecticidal Bufadienolide, Bryophyllin C, from Kalanchoe pinnata , 2000, Bioscience, biotechnology, and biochemistry.

[15]  T. Sen,et al.  Neuropsychopharmacological Profile of the Methanolic Fraction of Bryophyllum pinnatum Leaf Extract , 1999, The Journal of pharmacy and pharmacology.

[16]  N. Sultana,et al.  Triterpenoids and phenanthrenes from leaves of Bryophyllum pinnatum , 1989 .

[17]  J. Phillipson,et al.  Flavonol glycosides with acetyl substitution from Kalanchoe gracilis , 1989 .

[18]  S. Misra,et al.  Antifungal activity of leaf extracts of some higher plants. , 1979 .

[19]  A. K. Singla,et al.  Triterpenoids and sterols of Kalanchoe spathulata , 1976 .