Rapid Measurement of Residual Kanamycin Using Highly Specific Biomimetic Recognition Paper-Based Chip.

The development of highly specific biomimetic recognition material is a challenge for rapid detection of harmful residues in foodstuff. In this study, a paper-based boronate affinity metal-organic framework/molecularly imprinted polymer microfluidic chip (FZS-BA@MIP) was constructed based on the in situ construction strategy, which was also designed as a highly specific biomimetic recognition module. Here, the homogeneous zeolitic imidazole framework-8 (ZIF-8) membrane served as a great scaffold and enrichment layer. Besides, the recognition layer of MIP was prepared based on a highly oriented boronate affinity surface imprinting strategy. With the aid of the liquid flow channel, the highly specific enrichment and visual detection for antibiotic residues like kanamycin in actual products were achieved on the paper chip module of an integrated lateral flow platform. The whole analysis process could be accomplished within 30 min. In brief, this study offered a new integrated biomimetic recognition platform for visually detecting harmful veterinary residues containing cis-diols, which demonstrated promising commercial value in point-of-care testing of foodborne hazardous compounds.

[1]  S. Timur,et al.  Metal–Organic Frameworks Meet Molecularly Imprinted Polymers: Insights and Prospects for Sensor Applications , 2022, ACS applied materials & interfaces.

[2]  Deepak Kukkar,et al.  Recent advances in the synthesis of and sensing applications for metal-organic framework-molecularly imprinted polymer (MOF-MIP) composites , 2022, Critical Reviews in Environmental Science and Technology.

[3]  D. Zhao,et al.  Gradient Hierarchically Porous Structure for Rapid Capillary-Assisted Catalysis. , 2022, Journal of the American Chemical Society.

[4]  Zhiyong Guo,et al.  Ultrasensitive Competitive Lateral Flow Immunoassay with Visual Semiquantitative Inspection and Flexible Quantification Capabilities. , 2022, Analytical chemistry.

[5]  Rongrong Xing,et al.  Molecular imprinting and cladding produces antibody mimics with significantly improved affinity and specificity. , 2021, Science bulletin.

[6]  R. Liu,et al.  Metal-Tagged CRISPR/Cas12a Bioassay Enables Ultrasensitive and Highly Selective Evaluation of Kanamycin Bioaccumulation in Fish Samples. , 2021, Analytical chemistry.

[7]  Lingxin Chen,et al.  A Self-powered Rotating Paper-based Analytical Device for Sensing of Thrombin , 2021, Sensors and Actuators B: Chemical.

[8]  Ruiqi Su,et al.  Colorimetric detection of Aflatoxin B1 by using smartphone-assisted microfluidic paper-based analytical devices , 2021, Food Control.

[9]  Cody S. Carrell,et al.  Microfluidic Paper-Based Analytical Devices: From Design to Applications. , 2021, Chemical reviews.

[10]  Jinghua Yu,et al.  Ultrasensitive Microfluidic Paper-Based Electrochemical/Visual Analytical Device via Signal Amplification of Pd@Hollow Zn/Co Core-Shell ZIF67/ZIF8 Nanoparticles for Prostate-Specific Antigen Detection. , 2021, Analytical chemistry.

[11]  Huaping Peng,et al.  Regulating Valence States of Gold Nanocluster as a New Strategy for the Ultrasensitive Electrochemiluminescence Detection of Kanamycin. , 2021, Analytical chemistry.

[12]  Ruijun Li,et al.  Molecularly imprinted polymer-enhanced biomimetic paper-based analytical devices: A review. , 2021, Analytica chimica acta.

[13]  Minmin Wu,et al.  Simultaneous fluorescence determination of bisphenol A and its halogenated analogs based on a molecularly imprinted paper-based analytical device and a segment detection strategy. , 2021, Biosensors & bioelectronics.

[14]  Manman Liu,et al.  Nanobody-A versatile tool for cancer diagnosis and therapeutics. , 2021, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

[15]  Xiu‐Ping Yan,et al.  Functionalized Persistent Luminescence Nanoparticle-Based Aptasensor for Autofluorescence-free Determination of Kanamycin in Food Samples. , 2021, Analytical chemistry.

[16]  Moon Il Kim,et al.  Nanomaterial-mediated paper-based biosensors for colorimetric pathogen detection , 2020, TrAC Trends in Analytical Chemistry.

[17]  Y. Hu,et al.  Co-immobilization of laccase and ABTS onto amino-functionalized ionic liquid-modified magnetic chitosan nanoparticles for pollutants removal. , 2020, Journal of hazardous materials.

[18]  Yanqiang Zhou,et al.  Molecularly imprinted polymer coating on metal-organic frameworks for solid phase extraction of fluoroquinolones from water. , 2019, Journal of separation science.

[19]  Hong‐Cai Zhou,et al.  Metal-Organic Frameworks for Food Safety. , 2019, Chemical reviews.

[20]  Chaodi Xu,et al.  Cellulose Nanofiber @ Conductive Metal-Organic Frameworks for High Performance Flexible Supercapacitors. , 2019, ACS nano.

[21]  Hao Bai,et al.  Amine-responsive cellulose-based ratiometric fluorescent materials for real-time and visual detection of shrimp and crab freshness , 2019, Nature Communications.

[22]  A. Merkoçi,et al.  Paper Based Photoluminescent Sensing Platform with Recognition Sites for Tributyltin. , 2019, ACS sensors.

[23]  Jiean Tan,et al.  A fluorescent molecularly imprinted polymer using aptamer as a functional monomer for sensing of kanamycin , 2018, Sensors and Actuators B: Chemical.

[24]  Wenli Zhang,et al.  Magnetic nanoparticles combining teamed boronate affinity and surface imprinting for efficient selective recognition of glycoproteins under physiological pH , 2018, Chemical Engineering Journal.

[25]  Marjan Hassanzadeh,et al.  Preparation of bio-based keratin-derived magnetic molecularly imprinted polymer nanoparticles for the facile and selective separation of bisphenol A from water. , 2018, Journal of separation science.

[26]  X. Zou,et al.  A Fast and Scalable Approach for Synthesis of Hierarchical Porous Zeolitic Imidazolate Frameworks and One-Pot Encapsulation of Target Molecules. , 2017, Inorganic chemistry.

[27]  J. Marty,et al.  Disposable and portable aptamer functionalized impedimetric sensor for detection of kanamycin residue in milk sample , 2017 .

[28]  Yi Sun,et al.  Molecularly imprinted polymers for sample preparation and biosensing in food analysis: Progress and perspectives. , 2017, Biosensors & bioelectronics.

[29]  Jinghua Yu,et al.  A novel microfluidic paper-based colorimetric sensor based on molecularly imprinted polymer membranes for highly selective and sensitive detection of bisphenol A , 2017 .

[30]  Zhen Liu,et al.  Preparation of molecularly imprinted polymers specific to glycoproteins, glycans and monosaccharides via boronate affinity controllable–oriented surface imprinting , 2017, Nature Protocols.

[31]  Guobao Xu,et al.  A kanamycin sensor based on an electrosynthesized molecularly imprinted poly-o-phenylenediamine film on a single-walled carbon nanohorn modified glassy carbon electrode. , 2016, The Analyst.

[32]  Monya Baker,et al.  Antibody anarchy: A call to order , 2015, Nature.

[33]  Yang Chen,et al.  Boronate affinity materials for separation and molecular recognition: structure, properties and applications. , 2015, Chemical Society reviews.

[34]  Ligang Chen,et al.  Analysis of malachite green in aquatic products by carbon nanotube-based molecularly imprinted - matrix solid phase dispersion. , 2015, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

[35]  Jin Ye,et al.  Boronate-Affinity Glycan-Oriented Surface Imprinting: A New Strategy to Mimic Lectins for the Recognition of an Intact Glycoprotein and Its Characteristic Fragments. , 2015, Angewandte Chemie.

[36]  M. Baker.  Reproducibility crisis: Blame it on the antibodies , 2015, Nature.

[37]  Lu Wang,et al.  Flexible Solid-State Supercapacitor Based on a Metal-Organic Framework Interwoven by Electrochemically-Deposited PANI. , 2015, Journal of the American Chemical Society.

[38]  Yi-Fang Tian,et al.  Methodology Studies on Detection of Aminoglycoside Residues , 2015, Food Analytical Methods.

[39]  Vivien Marx,et al.  Proteomics: An atlas of expression , 2014, Nature.

[40]  Hui Li,et al.  An ultrasensitive homogeneous aptasensor for kanamycin based on upconversion fluorescence resonance energy transfer. , 2014, Biosensors & bioelectronics.

[41]  Zhen Liu,et al.  Affinity-tunable specific recognition of glycoproteins via boronate affinity-based controllable oriented surface imprinting , 2014 .

[42]  A. Terfort,et al.  Patterned Deposition of Metal‐Organic Frameworks onto Plastic, Paper, and Textile Substrates by Inkjet Printing of a Precursor Solution , 2013, Advanced materials.

[43]  Z. Lai,et al.  Effective separation of propylene/propane binary mixtures by ZIF-8 membranes , 2012 .

[44]  C. Ban,et al.  Gold nanoparticle-based colorimetric detection of kanamycin using a DNA aptamer. , 2011, Analytical biochemistry.

[45]  Bin Du,et al.  Label-free electrochemical immunosensor for sensitive detection of kanamycin , 2011 .

[46]  D. Paterson,et al.  Current use of aminoglycosides: indications, pharmacokinetics and monitoring for toxicity , 2011, Internal medicine journal.

[47]  Z. Lai,et al.  Rapid synthesis of zeolitic imidazolate framework-8 (ZIF-8) nanocrystals in an aqueous system. , 2011, Chemical communications.

[48]  E. Lundberg,et al.  A Genecentric Human Protein Atlas for Expression Profiles Based on Antibodies* , 2008, Molecular & Cellular Proteomics.

[49]  Yan Zhu,et al.  Rapid enzyme-linked immunosorbent assay and colloidal gold immunoassay for kanamycin and tobramycin in Swine tissues. , 2008, Journal of agricultural and food chemistry.

[50]  M. Koupparis,et al.  Direct determination of kanamycin in raw materials, veterinary formulation and culture media using a novel liquid chromatography-evaporative light scattering method , 2005 .

[51]  Z. Lai,et al.  Siliceous ZSM‐5 Membranes by Secondary Growth of b‐Oriented Seed Layers , 2004 .

[52]  E. Kaale,et al.  Determination of kanamycin in serum by solid-phase extraction, pre-capillary derivatization and capillary electrophoresis. , 2003, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.