Consequences of major and minor depression in later life: a study of disability, well-being and service utilization

BACKGROUND The consequences of major depression for disability, impaired well-being and service utilization have been studied primarily in younger adults. In all age groups the consequences of minor depression are virtually unknown. In later life, the increased co-morbidity with physical illness may modify the consequences of depression, warranting special study of the elderly. With rising numbers of elderly people, excess service utilization by depressed elderly represents an increasingly important issue. METHODS Based on a large, random community-based sample of older inhabitants of the Netherlands (55-85 years), the associations of major and minor depression with various indicators of disability, well-being and service utilization were assessed, controlling for potential confounding factors. Depression was diagnosed using a two-stage screening design. Diagnosis took place in all subjects with high depressive symptom levels and a random sample of those with low depressive symptom levels. The study sample consists of all participants to diagnostic interviews (N = 646). RESULTS As in younger adults, associations of both major and minor depression with disability and well-being remained significant after controlling for chronic disease and functional limitations. Adequate treatment is often not administered, even in subjects with major depression. As the vast majority of those depressed were recently seen by their general practitioners, treatment could have been provided in most cases. Bivariate analyses show that major and minor depression are associated with an excess use of non-mental health services, underscoring the importance of recognition. In multivariate analyses the evidence of excess service utilization was less compelling. CONCLUSIONS Both major and minor depression are consequential for well-being and disability, supporting efforts to improve the recognition and treatment in primary care. However, controlled trials are necessary to assess the impact this may have on service utilization.

[1]  R. Shewchuk,et al.  Somatic Complaints and the CES‐D , 1992, Journal of the American Geriatrics Society.

[2]  G. Kennedy,et al.  Persistence and remission of depressive symptoms in late life. , 1991, The American journal of psychiatry.

[3]  D H Freeman,et al.  Depressive symptoms in relation to physical health and functioning in the elderly. , 1986, American journal of epidemiology.

[4]  L. Kirmayer,et al.  Somatization and the recognition of depression and anxiety in primary care. , 1993, The American journal of psychiatry.

[5]  P. Duncan-Jones,et al.  Detecting anxiety and depression in general medical settings. , 1988, BMJ.

[6]  Linda Teri,et al.  6/Use of the Center for Epidemiological Studies-Depression Scale with Older Adults , 1986 .

[7]  J. van Limbeek,et al.  [A screening tool for depression in the elderly in the general population: the usefulness of Center for Epidemiological Studies Depression Scale (CES-D)]. , 1994, Tijdschrift voor gerontologie en geriatrie.

[8]  C. Caspersen,et al.  The prevalence of selected physical activities and their relation with coronary heart disease risk factors in elderly men: the Zutphen Study, 1985. , 1991, American journal of epidemiology.

[9]  R R Frerichs,et al.  Depression and physical illness: a multiwave, nonrecursive causal model. , 1984, Journal of health and social behavior.

[10]  A M Jette,et al.  The disablement process. , 1994, Social science & medicine.

[11]  R. Andersen,et al.  Societal and individual determinants of medical care utilization in the United States. , 1973, The Milbank Memorial Fund quarterly. Health and society.

[12]  T. Suurmeijer,et al.  Professional home care for the elderly: an application of the Andersen-Newman model in The Netherlands. , 1991, Social science & medicine.

[13]  J. Ormel,et al.  Depression and physical health in later life: results from the Longitudinal Aging Study Amsterdam (LASA). , 1997, Journal of affective disorders.

[14]  L. Robins,et al.  National Institute of Mental Health Diagnostic Interview Schedule. Its history, characteristics, and validity. , 1981, Archives of general psychiatry.

[15]  A. Stewart,et al.  The functioning and well-being of depressed patients. Results from the Medical Outcomes Study. , 1989, JAMA.

[16]  B. Ford International Classification of Impairments, Disabilities and Handicaps , 1984, Releve epidemiologique hebdomadaire.

[17]  B. Rovner,et al.  Depression and increased risk of mortality in the nursing home patient. , 1993, The American journal of medicine.

[18]  T. Usherwood,et al.  The Medical Outcomes Study Instrument (MOSI)--use of a new health status measure in Britain. , 1990, Family practice.

[19]  C. Sherbourne,et al.  Functioning and well-being outcomes of patients with depression compared with chronic general medical illnesses. , 1995, Archives of general psychiatry.

[20]  A. Boland Disability in America: Toward a National Agenda for Prevention , 1992 .

[21]  J Ormel,et al.  Disability and depression among high utilizers of health care. A longitudinal analysis. , 1992, Archives of general psychiatry.

[22]  J. van Limbeek,et al.  Criterion validity of the Center for Epidemiologic Studies Depression scale (CES-D): results from a community-based sample of older subjects in The Netherlands. , 1997, Psychological medicine.

[23]  H. Lentzner Autonomy and well-being in the aging population: Concepts and design of the longitudinal aging study Amsterdam: Edited by D. J. H. Deeg, C. P. M. Knipscheer and W. van Tilburg. Institute of Gerontology, The Netherlands, 1993. 303 pp. U.S. $ , 1995 .

[24]  Health, behavior, and aging. , 1990, Journal of gerontology.

[25]  Mark E. Williams,et al.  Diagnosis and Treatment of Depression in Late Life , 1992 .

[26]  D. Blazer,et al.  The Epidemiology of Late Life Depression , 1982, Journal of the American Geriatrics Society.

[27]  B. Penninx,et al.  Self-reports and general practitioner information on the presence of chronic diseases in community dwelling elderly. A study on the accuracy of patients' self-reports and on determinants of inaccuracy. , 1996, Journal of clinical epidemiology.

[28]  M. Prince,et al.  Impairment, disability and handicap as risk factors for depression in old age. The Gospel Oak Project V , 1997, Psychological Medicine.

[29]  J. Copeland,et al.  Alzheimer's Disease, Other Dementias, Depression and Pseudo-dementia: Prevalence, Incidence and Three-Year Outcome in Liverpool , 1992, British Journal of Psychiatry.

[30]  S. Folstein,et al.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. , 1975, Journal of psychiatric research.

[31]  J Ormel,et al.  Common mental disorders and disability across cultures. Results from the WHO Collaborative Study on Psychological Problems in General Health Care. , 1994, JAMA.

[32]  J. F. Phifer,et al.  Etiologic factors in the onset of depressive symptoms in older adults. , 1986, Journal of abnormal psychology.

[33]  T. Craig,et al.  Current medication use and symptoms of depression in a general population. , 1978, The American journal of psychiatry.

[34]  A. Beekman,et al.  Major and minor depression in later life: a study of prevalence and risk factors. , 1995, Journal of affective disorders.

[35]  R. Dixon,et al.  Measurement properties of the Center for Epidemiological Studies Depression Scale (CES-D) in older populations. , 1990 .

[36]  M. Prince,et al.  Impairment, Disability and Handicap as Risk Factors for Depression in Old Age , 1997 .

[37]  B. Gurland The impact of depression on quality of life of the elderly. , 1992, Clinics in geriatric medicine.

[38]  H. Cohen,et al.  Depression in elderly hospitalized patients with medical illness. , 1988, Archives of internal medicine.

[39]  B. Neugarten Adaptation and the Life Cycle , 1976 .

[40]  F. Wolinsky,et al.  A Different Perspective on Health and Health Services Utilization , 1988, Annual Review of Gerontology and Geriatrics.

[41]  J. Ormel,et al.  Outcome of depression and anxiety in primary care. A three-wave 3 1/2-year study of psychopathology and disability. , 1993, Archives of general psychiatry.

[42]  P. Bijur,et al.  Hierarchy of characteristics associated with depressive symptoms in an urban elderly sample. , 1989, The American journal of psychiatry.

[43]  Pearl A. Dykstra,et al.  Living arrangements and social networks of older adults , 1996 .

[44]  B. Gurland,et al.  Depression and disability in the elderly: Reciprocal relations and changes with age , 1988 .

[45]  L. Radloff The CES-D Scale , 1977 .

[46]  S. Murrell,et al.  Reliability and validity of five mental health scales in older persons. , 1983, Journal of gerontology.