Pharmacological GLUT3 salvage augments the efficacy of vitamin C-induced TET2 restoration in acute myeloid leukemia
暂无分享,去创建一个
Junshik Hong | Sung-Soo Yoon | Y. Koh | Dong-Yeop Shin | Shanshan Pei | M. Ko | J. Byun | Dongchan Kim | Jihyun Park | Eun-Gyeong Park | Jun Liu | D. Shin | Su-Gyeong Min | S. Yoon
[1] R. Shiekhattar,et al. Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia , 2023, Cell reports.
[2] B. Manavathi,et al. AMPK: An odyssey of a metabolic regulator, a tumor suppressor, and now a contextual oncogene. , 2022, Biochimica et biophysica acta. Reviews on cancer.
[3] M. Voso,et al. Vitamin C Deficiency in Patients With Acute Myeloid Leukemia , 2022, Frontiers in Oncology.
[4] M. Hampton,et al. Ascorbate Inhibits Proliferation and Promotes Myeloid Differentiation in TP53-Mutant Leukemia , 2021, Frontiers in Oncology.
[5] H. Lalić,et al. AICAr, a Widely Used AMPK Activator with Important AMPK-Independent Effects: A Systematic Review , 2021, Cells.
[6] L. Nováková,et al. Vitamin C—Sources, Physiological Role, Kinetics, Deficiency, Use, Toxicity, and Determination , 2021, Nutrients.
[7] J. Qin,et al. GLUT3 induced by AMPK/CREB1 axis is key for withstanding energy stress and augments the efficacy of current colorectal cancer therapies , 2020, Signal Transduction and Targeted Therapy.
[8] Junshik Hong,et al. Decreased vitamin C uptake mediated by SLC2A3 promotes leukaemia progression and impedes TET2 restoration , 2020, British Journal of Cancer.
[9] M. Chorilli,et al. Vitamin c: One compound, several uses. Advances for delivery, efficiency and stability. , 2020, Nanomedicine : nanotechnology, biology, and medicine.
[10] M. Nicolas,et al. Acadesine Circumvents Azacitidine Resistance in Myelodysplastic Syndrome and Acute Myeloid Leukemia , 2019, International journal of molecular sciences.
[11] Eric Song,et al. ERVmap analysis reveals genome-wide transcription of human endogenous retroviruses , 2018, Proceedings of the National Academy of Sciences.
[12] Fei Lan,et al. Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer , 2018, Nature.
[13] N. Cabezas-Wallscheid,et al. Vitamin C: C-ing a New Way to Fight Leukemia. , 2017, Cell stem cell.
[14] O. Abdel-Wahab,et al. Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression , 2017, Cell.
[15] R. Deberardinis,et al. Ascorbate regulates haematopoietic stem cell function and leukaemogenesis , 2017, Nature.
[16] Saijuan Chen,et al. Enhanced Fructose Utilization Mediated by SLC2A5 Is a Unique Metabolic Feature of Acute Myeloid Leukemia with Therapeutic Potential. , 2016, Cancer cell.
[17] Peter A. Jones,et al. Vitamin C increases viral mimicry induced by 5-aza-2′-deoxycytidine , 2016, Proceedings of the National Academy of Sciences.
[18] L. Notarangelo,et al. Lentiviral hematopoietic stem cell gene therapy for X-linked severe combined immunodeficiency , 2016, Science Translational Medicine.
[19] K. Helin,et al. Role of TET enzymes in DNA methylation, development, and cancer , 2016, Genes & development.
[20] O. Bernard,et al. TET proteins and the control of cytosine demethylation in cancer , 2015, Genome Medicine.
[21] R. Winn,et al. The soft agar colony formation assay. , 2014, Journal of visualized experiments : JoVE.
[22] D. Douer,et al. Adding ascorbic acid to arsenic trioxide produces limited benefit in patients with acute myeloid leukemia excluding acute promyelocytic leukemia , 2014, Annals of Hematology.
[23] I. Lossos,et al. Recurrent mutations in epigenetic regulators, RHOA and FYN kinase in peripheral T cell lymphomas , 2014, Nature Genetics.
[24] C Haferlach,et al. Landscape of genetic lesions in 944 patients with myelodysplastic syndromes , 2013, Leukemia.
[25] Zechen Chong,et al. Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals. , 2013, Journal of the American Chemical Society.
[26] William A. Pastor,et al. TETonic shift: biological roles of TET proteins in DNA demethylation and transcription , 2013, Nature Reviews Molecular Cell Biology.
[27] E. González-Barca,et al. Acadesine for patients with relapsed/refractory chronic lymphocytic leukemia (CLL): a multicenter phase I/II study , 2012, Cancer Chemotherapy and Pharmacology.
[28] B. Halliwell. Vitamin C: antioxidant or pro-oxidant in vivo? , 1996, Free radical research.