Improving a CAD system using bilateral information

Computer Aided Detection (CAD) mammographic systems are used in medicine to assist radiologists in the evaluation of mammographic images. The aim of this work is to compare the results of a developed single-image CAD system with a new one, dual-image CAD, that adds registration information of bilateral mammographic images in the training step of the former system. The evaluation of the different registration methods is performed using similarity measures. Receiver Operating Characteristic (ROC) analysis and Free Receiver Operating Characteristics (FROC) analysis are used to compare the results of both CAD systems. At a sensitivity of 80%, the false positives per image was 1.68 for the single-image CAD system and 0.90 for the dual-image CAD system. The results shows the benefits of integrating bilateral information into the CAD system.

[1]  Daniel Rueckert,et al.  Nonrigid registration using free-form deformations: application to breast MR images , 1999, IEEE Transactions on Medical Imaging.

[2]  G. G. Stokes.  "J." , 1890, The New Yale Book of Quotations.

[3]  E. Denton,et al.  Eigendetection of masses considering false positive reduction and breast density information. , 2008, Medical physics.

[4]  Berkman Sahiner,et al.  Evaluating computer-aided detection algorithms. , 2007, Medical physics.

[5]  S. Obenauer,et al.  Comparative study in patients with microcalcifications: full-field digital mammography vs screen-film mammography , 2002, European Radiology.

[6]  Jan Flusser,et al.  Image registration methods: a survey , 2003, Image Vis. Comput..

[7]  L. Tabár,et al.  REDUCTION IN MORTALITY FROM BREAST CANCER AFTER MASS SCREENING WITH MAMMOGRAPHY Randomised Trial from the Breast Cancer Screening Working Group of the Swedish National Board of Health and Welfare , 1985, The Lancet.

[8]  Xavier Lladó,et al.  Comparison of registration methods using mamographic images , 2010, 2010 IEEE International Conference on Image Processing.

[9]  Richard H. Moore,et al.  THE DIGITAL DATABASE FOR SCREENING MAMMOGRAPHY , 2007 .

[10]  Ian W. Ricketts,et al.  The Mammographic Image Analysis Society digital mammogram database , 1994 .

[11]  Etta D Pisano,et al.  Comparison of full-field digital mammography to screen-film mammography with respect to diagnostic accuracy of lesion characterization in breast tissue biopsy specimens. , 2002, Academic radiology.

[12]  T. Freer,et al.  Screening mammography with computer-aided detection: prospective study of 12,860 patients in a community breast center. , 2001, Radiology.