Overexpression of the human NFM subunit in transgenic mice modifies the level of endogenous NFL and the phosphorylation state of NFH subunits
暂无分享,去创建一个
J. Trojanowski | V. Lee | G. Elder | D. Nelson | R. Lazzarini | P. Tu
[1] J. Trojanowski,et al. Modulation of axon diameter and neurofilaments by hypomyelinating Schwann cells in transgenic mice , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[2] G. Elder,et al. Enhancer trapping by a human mid-sized neurofilament transgene reveals unexpected patterns of neuronal enhancer activity. , 1994, Brain research. Molecular brain research.
[3] R. Lazzarini,et al. Age-associated and cell-type-specific neurofibrillary pathology in transgenic mice expressing the human midsized neurofilament subunit , 1994, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[4] R. Nixon,et al. Phosphorylation on carboxyl terminus domains of neurofilament proteins in retinal ganglion cell neurons in vivo: influences on regional neurofilament accumulation, interneurofilament spacing, and axon caliber , 1994, The Journal of cell biology.
[5] T. Gotow,et al. Dephosphorylation of the largest neurofilament subunit protein influences the structure of crossbridges in reassembled neurofilaments. , 1994, Journal of cell science.
[6] A. Peterson,et al. Neurofilament-deficient axons and perikaryal aggregates in viable transgenic mice expressing a neurofilament-β-galactosidase fusion protein , 1994, Neuron.
[7] R. Liem,et al. Assembly of type IV neuronal intermediate filaments in nonneuronal cells in the absence of preexisting cytoplasmic intermediate filaments , 1993, The Journal of cell biology.
[8] P. Wong,et al. Neurofilaments are obligate heteropolymers in vivo , 1993, The Journal of cell biology.
[9] J. Trojanowski,et al. Expression of neuronal and glial polypeptides during histogenesis of the human cerebellar cortex including observations on the dentate nucleus , 1993, The Journal of comparative neurology.
[10] John Q. Trojanowski,et al. Abnormal tau phosphorylation at Ser396 in alzheimer's disease recapitulates development and contributes to reduced microtubule binding , 1993, Neuron.
[11] L. Alhonen,et al. Tissue-specific expression of rat light neurofilament promoter-driven reporter gene in transgenic mice. , 1993, Biochemical and biophysical research communications.
[12] T. Sakaguchi,et al. Reduced diameter and conduction velocity of myelinated fibers in the sciatic nerve of a neurofilament-deficient mutant quail , 1993, Neuroscience Letters.
[13] L. Cork,et al. Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease , 1993, Cell.
[14] O. Ohara,et al. Neurofilament deficiency in quail caused by nonsense mutation in neurofilament-L gene , 1993, The Journal of cell biology.
[15] D. Houle,et al. Different posttranscriptional controls for the human neurofilament light and heavy genes in transgenic mice. , 1993, Brain research. Molecular brain research.
[16] R. Nixon,et al. The Regulation of Neurofilament Protein Dynamics by Phosphorylation: Clues to Neurofibrillary Pathobiology , 1993, Brain pathology.
[17] F. Pieper,et al. Regulation of vimentin expression in cultured epithelial cells. , 1992, European journal of biochemistry.
[18] G. Elder,et al. Expression of human mid-sized neurofilament subunit in transgenic mice. , 1992, Brain research. Molecular brain research.
[19] D. Houle,et al. Intragenic regulatory elements contribute to transcriptional control of the neurofilament light gene. , 1992, Gene.
[20] M. Mizutani,et al. Defective expression of neurofilament protein subunits in hereditary hypotrophic axonopathy of quail. , 1992, Laboratory investigation; a journal of technical methods and pathology.
[21] J. Julien,et al. Origin of the two mRNA species for the human neurofilament light gene. , 1992, Biochemistry and cell biology = Biochimie et biologie cellulaire.
[22] M. Schwartz,et al. Negative regulatory regions are present upstream in the three mouse neurofilament genes. , 1992, Brain research. Molecular brain research.
[23] Scott T. Brady,et al. Local modulation of neurofilament phosphorylation, axonal caliber, and slow axonal transport by myelinating Schwann cells , 1992, Cell.
[24] L. Landmesser,et al. Temporal and spatial modulation of a cytoskeletal antigen during peripheral axonal pathfinding , 1992, Neuron.
[25] Virginia M. Y. Lee,et al. Dynamics of mammalian high‐molecular‐weight neurofilament subunit phosphorylation in cultured rat sympathetic neurons , 1991, Journal of neuroscience research.
[26] V. Lee,et al. Individual neurofilament subunits reassembled in vitro exhibit unique biochemical, morphological and immunological properties , 1991, Brain Research.
[27] J. Trojanowski,et al. Molecular milestones that signal axonal maturation and the commitment of human spinal cord precursor cells to the neuronal or glial phenotype in development , 1991, The Journal of comparative neurology.
[28] W. Ip,et al. Antibody labeling of bovine neurofilaments: implications on the structure of neurofilament sidearms. , 1991, Journal of structural biology.
[29] K. Mikoshiba,et al. Nerve growth factor rapidly induces expression of the 68-kDa neurofilament gene by posttranscriptional modification in PC12h-R cells. , 1990, The Journal of biological chemistry.
[30] K. Mikoshiba,et al. Structure of the 68-kDa neurofilament gene and regulation of its expression. , 1990, The Journal of biological chemistry.
[31] J. Gearhart,et al. Expression of NF-L in both neuronal and nonneuronal cells of transgenic mice: increased neurofilament density in axons without affecting caliber , 1990, The Journal of cell biology.
[32] E. Fuchs,et al. Elucidating the early stages of keratin filament assembly , 1990, The Journal of cell biology.
[33] J. Dengler,et al. Differential screening of murine ascites cDNA libraries by means of in vitro transcripts of cell-cycle-phase-specific cDNA and digital image processing. , 1990, Gene.
[34] S. Chin,et al. Expression of rat neurofilament proteins NF-L and NF-M in transfected non-neuronal cells. , 1989, European journal of cell biology.
[35] W. Franke,et al. Spontaneous losses of control of cytokeratin gene expression in transformed, non-epithelial human cells occurring at different levels of regulation , 1989, Cell.
[36] H. Gainer,et al. Spatial and temporal expression of phosphorylated and non-phosphorylated forms of neurofilament proteins in the developing nervous system of Xenopus laevis. , 1989, Brain research. Developmental brain research.
[37] D. Kulesh,et al. Posttranslational regulation of keratins: degradation of mouse and human keratins 18 and 8 , 1989, Molecular and cellular biology.
[38] M. Selzer,et al. Lamprey neurofilaments combine in one subunit the features of each mammalian NF triplet protein but are highly phosphorylated only in large axons , 1989, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[39] M. L. Schmidt,et al. Distribution of tau proteins in the normal human central and peripheral nervous system. , 1989, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[40] J. Trojanowski,et al. Alzheimer disease tangles share immunological similarities with multiphosphorylation repeats in the two large neurofilament proteins. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[41] F. Grosveld,et al. Transcriptional and post-transcriptional effects of nerve growth factor on expression of the three neurofilament subunits in PC-12 cells. , 1988, The Journal of biological chemistry.
[42] L. Otvos,et al. Identification of the major multiphosphorylation site in mammalian neurofilaments. , 1988, Proceedings of the National Academy of Sciences of the United States of America.
[43] R. Lasek,et al. Neurofilaments are spaced randomly in the radial dimension of axons , 1988, Journal of neurocytology.
[44] J. Julien,et al. Expression and assembly of a human neurofilament protein in transgenic mice provide a novel neuronal marking system. , 1987, Genes & development.
[45] J. Trojanowski,et al. Monoclonal antibodies distinguish several differentially phosphorylated states of the two largest rat neurofilament subunits (NF-H and NF-M) and demonstrate their existence in the normal nervous system of adult rats , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[46] J. Trojanowski,et al. Two-stage expression of neurofilament polypeptides during rat neurogenesis with early establishment of adult phosphorylation patterns , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[47] D. Nelson,et al. The human mid‐size neurofilament subunit: a repeated protein sequence and the relationship of its gene to the intermediate filament gene family. , 1987, The EMBO journal.
[48] J W Griffin,et al. Neurofilament gene expression: a major determinant of axonal caliber. , 1987, Proceedings of the National Academy of Sciences of the United States of America.
[49] V. Lee,et al. Phosphate dependent and independent neurofilament epitopes in the axonal swellings of patients with motor neuron disease and controls. , 1987, Laboratory investigation; a journal of technical methods and pathology.
[50] E. Fuchs,et al. The transfection of epidermal keratin genes into fibroblasts and simple epithelial cells: Evidence for inducing a type I keratin by a type II gene , 1987, Cell.
[51] S. Lewis,et al. Anomalous placement of introns in a member of the intermediate filament multigene family: an evolutionary conundrum , 1986, Molecular and cellular biology.
[52] J. Trojanowski,et al. Expression of neurofilament subunits in neurons of the central and peripheral nervous system: an immunohistochemical study with monoclonal antibodies , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[53] J. Trojanowski,et al. Novel monoclonal antibodies provide evidence for the in situ existence of a nonphosphorylated form of the largest neurofilament subunit , 1986, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[54] K. Angelides,et al. Characterization of mammalian neurofilament triplet proteins. Subunit stoichiometry and morphology of native and reconstituted filaments. , 1985, The Journal of biological chemistry.
[55] J W Griffin,et al. Control of axonal caliber by neurofilament transport , 1984, The Journal of cell biology.
[56] J. Trojanowski,et al. A morphometric study of the endocytosis of wheat germ agglutinin-horseradish peroxidase conjugates by retinal ganglion cells in the rat , 1983, Brain Research.
[57] F. Chiu,et al. Bulk Preparation of CNS Cytoskeleton and the Separation of Individual Neurofilament Proteins by Gel Filtration: Dye‐Binding Characteristics and Amino Acid Compositions , 1982, Journal of neurochemistry.
[58] R. Liem,et al. Purification of individual components of the neurofilament triplet: filament assembly from the 70 000-dalton subunit. , 1982, Biochemistry.
[59] K. Weber,et al. Self-assembly in Vitro of the 68,000 molecular weight component of the mammalian neurofilament triplet proteins into intermediate-sized filaments. , 1981, Journal of molecular biology.
[60] S. Tapscott,et al. Neuronal precursor cells in the chick neural tube express neurofilament proteins , 1981, Nature.
[61] H. Wiśniewski,et al. Partial purification of neurofilament subunits from bovine brains and studies on neurofilament assembly , 1981, The Journal of cell biology.
[62] C. Marotta,et al. Characterization and Comparison of Neurofilament Proteins from Rat and Mouse CNS , 1981, Journal of neurochemistry.
[63] R. Lasek,et al. Preparation of Neurofilament Protein from Guinea Pig Peripheral Nerve and Spinal Cord , 1980, Journal of neurochemistry.
[64] M. Shelanski,et al. Intermediate filaments in nervous tissues , 1978, The Journal of cell biology.
[65] W. Schlaepfer,et al. Neurofilament proteins of rat peripheral nerve and spinal cord , 1978, The Journal of cell biology.
[66] R. Lasek,et al. The slow component of axonal transport. Identification of major structural polypeptides of the axon and their generality among mammalian neurons , 1975, The Journal of cell biology.
[67] K Weber,et al. Intermediate filaments: structure, dynamics, function, and disease. , 1994, Annual review of biochemistry.
[68] J Q Trojanowski,et al. Epitope map of neurofilament protein domains in cortical and peripheral nervous system Lewy bodies. , 1991, The American journal of pathology.
[69] C. DiLullo,et al. Transient expression of a neurofilament protein by replicating neuroepithelial cells of the embryonic chick brain. , 1985, Developmental biology.
[70] A. Bignami,et al. Intermediate filaments in nervous tissue. , 1985, Cell and muscle motility.
[71] M. Kurokawa,et al. MORPHOLOGICAL AND BIOCHEMICAL CHARACTERISATION OF NEUROFILAMENTS ISOLATED FROM THE RAT PERIPHERAL NERVE , 1980 .