Limitations of gene editing assessments in human preimplantation embryos

[1]  R. Jaenisch,et al.  Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing , 2021, Nature Communications.

[2]  G. Feng,et al.  Efficient embryonic homozygous gene conversion via RAD51-enhanced interhomolog repair , 2021, Cell.

[3]  R. Tupler,et al.  Mosaicism in Human Health and Disease. , 2020, Annual review of genetics.

[4]  S. Tsang,et al.  Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos , 2020, Cell.

[5]  K. Niakan,et al.  Frequent loss of heterozygosity in CRISPR-Cas9–edited early human embryos , 2020, Proceedings of the National Academy of Sciences.

[6]  G. Burgio.  Gene conversion following CRISPR/Cas9 DNA cleavage: an overlooked effect , 2020, Gene Therapy.

[7]  M. Poo,et al.  Cloning of a gene-edited macaque monkey by somatic cell nuclear transfer , 2019, National science review.

[8]  A. Bradley,et al.  Erratum: Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements , 2018, Nature Biotechnology.

[9]  James N. Hughes,et al.  Large deletions induced by Cas9 cleavage , 2018, Nature.

[10]  G. Church,et al.  Inter-homologue repair in fertilized human eggs? , 2017, bioRxiv.

[11]  Jianhui Gong,et al.  Correction of a pathogenic gene mutation in human embryos , 2017, Nature.

[12]  Caixia Liu,et al.  The comparison of the performance of four whole genome amplification kits on ion proton platform in copy number variation detection , 2017, Bioscience reports.

[13]  J. Ecker,et al.  Functional Human Oocytes Generated by Transfer of Polar Body Genomes. , 2017, Cell stem cell.

[14]  D. Cram,et al.  The Performance of Whole Genome Amplification Methods and Next-Generation Sequencing for Pre-Implantation Genetic Diagnosis of Chromosomal Abnormalities. , 2015, Journal of genetics and genomics = Yi chuan xue bao.

[15]  J. Doudna,et al.  The new frontier of genome engineering with CRISPR-Cas9 , 2014, Science.

[16]  T. Mashimo,et al.  Allele-specific genome editing and correction of disease-associated phenotypes in rats using the CRISPR–Cas platform , 2014, Nature Communications.

[17]  Yoshitaka Fujihara,et al.  Generation of mutant mice by pronuclear injection of circular plasmid expressing Cas9 and single guided RNA , 2013, Scientific Reports.

[18]  S. Mitalipov,et al.  Human Embryonic Stem Cells Derived by Somatic Cell Nuclear Transfer , 2013, Cell.

[19]  James E. DiCarlo,et al.  RNA-Guided Human Genome Engineering via Cas9 , 2013, Science.

[20]  R. Weinberg,et al.  Ma et al. reply , 2008, Nature.

[21]  D. Cooper,et al.  Gene conversion: mechanisms, evolution and human disease , 2007, Nature Reviews Genetics.

[22]  K. Sermon,et al.  Whole-genome multiple displacement amplification from single cells , 2006, Nature Protocols.

[23]  M. Brenneman,et al.  Repair of site-specific double-strand breaks in a mammalian chromosome by homologous and illegitimate recombination , 1997, Molecular and cellular biology.

[24]  Mario R. Capecchi,et al.  High frequency targeting of genes to specific sites in the mammalian genome , 1986, Cell.