Targeting aging-associated pathways: a novel therapeutic approach for cancer

[1]  Feng Min,et al.  Carnosic Acid Suppresses the Development of Oral Squamous Cell Carcinoma via Mitochondrial-Mediated Apoptosis , 2021, Frontiers in Oncology.

[2]  Gayathri N. Silva,et al.  Carfilzomib: A Promising Proteasome Inhibitor for the Treatment of Relapsed and Refractory Multiple Myeloma , 2021, Frontiers in Oncology.

[3]  W. El-Deiry,et al.  Targeting the Integrated Stress Response in Cancer Therapy , 2021, Frontiers in Pharmacology.

[4]  S. Uddin,et al.  Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids. , 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[5]  K. Chakraborty,et al.  Recent advances in understanding the role of proteostasis , 2021, Faculty reviews.

[6]  Yun-Ping Lim,et al.  Piperlongumine, a Potent Anticancer Phytotherapeutic, Induces Cell Cycle Arrest and Apoptosis In Vitro and In Vivo through the ROS/Akt Pathway in Human Thyroid Cancer Cells , 2021, Cancers.

[7]  Nektarios Tavernarakis,et al.  Autophagy in healthy aging and disease , 2021, Nature Aging.

[8]  M. Kumar,et al.  The Therapeutic Potential of Wogonin Observed in Preclinical Studies , 2021, Evidence-based complementary and alternative medicine : eCAM.

[9]  H. Ren,et al.  The Cross-Links of Endoplasmic Reticulum Stress, Autophagy, and Neurodegeneration in Parkinson’s Disease , 2021, Frontiers in Aging Neuroscience.

[10]  M. Aschner,et al.  Allicin and Digestive System Cancers: From Chemical Structure to Its Therapeutic Opportunities , 2021, Frontiers in Oncology.

[11]  J. Simal-Gándara,et al.  Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin , 2021, Cancer cell international.

[12]  P. Henneke,et al.  From Flies to Men: ROS and the NADPH Oxidase in Phagocytes , 2021, Frontiers in Cell and Developmental Biology.

[13]  S. Apcher,et al.  Isoginkgetin derivative IP2 enhances the adaptive immune response against tumor antigens , 2021, Communications biology.

[14]  B. Schumacher,et al.  Principles of the Molecular and Cellular Mechanisms of Aging. , 2021, The Journal of investigative dermatology.

[15]  Wenwen Zhao,et al.  Endoplasmic reticulum stress, cell death and tumor: Association between endoplasmic reticulum stress and the apoptosis pathway in tumors , 2021, Oncology reports.

[16]  Jin-jian Lu,et al.  Natural Products in Cancer Therapy: Past, Present and Future , 2021, Natural Products and Bioprospecting.

[17]  P. Li,et al.  Quercetin: Its Main Pharmacological Activity and Potential Application in Clinical Medicine , 2020, Oxidative medicine and cellular longevity.

[18]  J. Pei,et al.  Myricetin: A review of the most recent research. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[19]  M. Ashrafizadeh,et al.  Apigenin as Tumor Suppressor in Cancers: Biotherapeutic Activity, Nanodelivery, and Mechanisms With Emphasis on Pancreatic Cancer , 2020, Frontiers in Chemistry.

[20]  J. López-González,et al.  The Double-Edge Sword of Autophagy in Cancer: From Tumor Suppression to Pro-tumor Activity , 2020, Frontiers in Oncology.

[21]  Yue Liu,et al.  Mitochondria as a target in cancer treatment , 2020, MedComm.

[22]  Shu-wen Yu,et al.  Myricetin induces apoptosis and autophagy by inhibiting PI3K/Akt/mTOR signalling in human colon cancer cells , 2020, BMC Complementary Medicine and Therapies.

[23]  M. Sharifi-Rad,et al.  Lifestyle, Oxidative Stress, and Antioxidants: Back and Forth in the Pathophysiology of Chronic Diseases , 2020, Frontiers in Physiology.

[24]  K. Yang,et al.  ω-hydroxyundec-9-enoic acid induction of breast cancer cells apoptosis through generation of mitochondrial ROS and phosphorylation of AMPK , 2020, Archives of Pharmacal Research.

[25]  Hyung-Ryong Kim,et al.  Endoplasmic Reticulum (ER) Stress Response Failure in Diseases. , 2020, Trends in cell biology.

[26]  Hongxiang Wang,et al.  Combination of an Autophagy Inducer and an Autophagy Inhibitor: A Smarter Strategy Emerging in Cancer Therapy , 2020, Frontiers in Pharmacology.

[27]  B. Perillo,et al.  ROS in cancer therapy: the bright side of the moon , 2020, Experimental & Molecular Medicine.

[28]  Zhan-guo Wang,et al.  Antitumor activity and mechanism of costunolide and dehydrocostus lactone: Two natural sesquiterpene lactones from the Asteraceae family. , 2020, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[29]  W. Yap,et al.  Honokiol: A Review of Its Anticancer Potential and Mechanisms , 2019, Cancers.

[30]  Y. Seo,et al.  Understanding of ROS-Inducing Strategy in Anticancer Therapy , 2019, Oxidative medicine and cellular longevity.

[31]  A. Thorburn,et al.  Autophagy in cancer: moving from understanding mechanism to improving therapy responses in patients , 2019, Cell Death & Differentiation.

[32]  Anita Saraf,et al.  Mitochondrial dysfunction and oxidative stress in heart disease , 2019, Experimental & Molecular Medicine.

[33]  E. Krüger,et al.  Contribution of the Unfolded Protein Response (UPR) to the Pathogenesis of Proteasome-Associated Autoinflammatory Syndromes (PRAAS) , 2019, Front. Immunol..

[34]  Lei Zhou,et al.  ATF6 regulates the development of chronic pancreatitis by inducing p53-mediated apoptosis , 2019, Cell Death & Disease.

[35]  M. Ciriolo,et al.  Targeting Glutathione Metabolism: Partner in Crime in Anticancer Therapy , 2019, Nutrients.

[36]  Z. Li,et al.  Ampelopsin inhibits human glioma through inducing apoptosis and autophagy dependent on ROS generation and JNK pathway. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[37]  Yang Liu,et al.  Brusatol, an NRF2 inhibitor for future cancer therapeutic , 2019, Cell & Bioscience.

[38]  M. Shariati,et al.  Luteolin, a flavonoid, as an anticancer agent: A review. , 2019, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[39]  Yongheng Bai,et al.  Nrf2 in cancers: A double‐edged sword , 2019, Cancer medicine.

[40]  B. Dwarakanath,et al.  Radiation induces EIF2AK3/PERK and ERN1/IRE1 mediated pro-survival autophagy , 2019, Autophagy.

[41]  Songbo Xie,et al.  Therapeutic targeting of cellular stress responses in cancer , 2018, Thoracic cancer.

[42]  J. E. Park,et al.  Next‐generation proteasome inhibitors for cancer therapy , 2018, Translational research : the journal of laboratory and clinical medicine.

[43]  C. Franceschi,et al.  The Continuum of Aging and Age-Related Diseases: Common Mechanisms but Different Rates , 2018, Front. Med..

[44]  Wei Zheng,et al.  Natural autophagy blockers, dauricine (DAC) and daurisoline (DAS), sensitize cancer cells to camptothecin-induced toxicity , 2017, Oncotarget.

[45]  D. Mercola,et al.  When Anti-Aging Studies Meet Cancer Chemoprevention: Can Anti-Aging Agent Kill Two Birds with One Blow? , 2015, Current Pharmacology Reports.

[46]  M. Mi,et al.  Ampelopsin Induces Cell Growth Inhibition and Apoptosis in Breast Cancer Cells through ROS Generation and Endoplasmic Reticulum Stress Pathway , 2014, PloS one.