Pilomatrixoma. Review of 205 cases.

AIMS To determine the incidence and clinical features of patients diagnosed with pilomatrixoma. PATIENTS AND METHOD A retrospective analysis was made of 205 cases of pilomatrixoma diagnosed according to clinical and histological criteria, with an evaluation of the incidence, patient age at presentation, gender, lesion location and size, single or multiple presentation, differential diagnosis, histopathological and clinical findings and relapses. RESULTS Pilomatrixoma was seen to account for 1.04% of all benign skin lesions. It tended to present in pediatric patients--almost 50% corresponding to individuals under 20 years of age--with a slight male predilection (107/98). Approximately 75% of all cases presented as single lesions measuring less than 15 mm in diameter. Multiple presentations were seen in 2.43% of cases. The most frequent locations were the head and orofacial zones (particularly the parotid region), with over 50% of all cases, followed by the upper (23.9%) and lower limbs (12.7%). Only one relapse was documented following simple lesion excision. CONCLUSIONS The frequency of pilomatrixomas was 1.04% of all benign skin lesions--the lesions being predominantly located in the maxillofacial area. Due to the benign features of this disorder, simple removal of the lesion is considered to be the treatment of choice, and is associated with a very low relapse rate.

[1]  C. Noli,et al.  Isotretinoin in the treatment of multiple benign pilomatrixomas in a mixed-breed dog. , 2005, Veterinary dermatology.

[2]  J. Hwang,et al.  The Common Ultrasonographic Features of Pilomatricoma , 2005, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[3]  J. Meara,et al.  Pilomatrixoma:: A Review of 346 Cases , 2003, Plastic and reconstructive surgery.

[4]  A. G. Corchón,et al.  Pilomatricoma o epitelioma calcificante de Malherbe , 2003 .

[5]  C. A. Hughes,et al.  Head and neck pilomatrixoma in children. , 2001, Archives of otolaryngology--head & neck surgery.

[6]  N. Mikhaeel,et al.  Malignant pilomatrixoma with multiple local recurrences and distant metastases: a case report and review of the literature. , 2001, Clinical oncology (Royal College of Radiologists (Great Britain)).

[7]  H. Stalsberg,et al.  Pilomatrix carcinoma with multiple metastases: report of a case and review of the literature. , 1999, European journal of cancer.

[8]  J. Triglia,et al.  Pilomatrixoma of the head and neck in children: a study of 38 cases and a review of the literature. , 1998, Archives of otolaryngology--head & neck surgery.

[9]  P. W. Bowers,et al.  A clinical review of 209 pilomatricomas. , 1998, Journal of the American Academy of Dermatology.

[10]  Cosme Gay-Escoda,et al.  Pilomatrixoma de la región parotídea , 1989 .

[11]  J. Bunkis,et al.  Pilomatrixoma presenting as a parotid mass. , 1986, Plastic and reconstructive surgery.

[12]  R. O'Grady,et al.  Pilomatrixoma (benign calcifying epithelioma of Malherbe). , 1981, Ophthalmology.

[13]  J. Rodríguez Cervical lymph nodes tuberculosis , 1979 .

[14]  C. Gay Escoda,et al.  [Cervical lymph nodes tuberculosis]. , 1979, Anales otorrinolaringologicos ibero-americanos.

[15]  F. W. Moehlenbeck Pilomatrixoma (calcifying epithelioma). A statistical study. , 1973, Archives of dermatology.

[16]  E. B. Helwig,et al.  Pilomatrixoma (calcifying epithelioma). , 1961, Archives of dermatology.

[17]  Geiser Jd [Malherbe's calcified epithelioma]. , 1959 .

[18]  J. Geiser [Malherbe's calcified epithelioma]. , 1959, Annales de dermatologie et de syphiligraphie.