Changes in classic and alternative pathways of bile acid synthesis in chronic liver disease.

[1]  L. Swell,et al.  Bile Acid Metabolism in Cirrhosis. VIII. Quantitative Evaluation of Bile Acid Synthesis From [7β‐3H]7α‐Hydroxycholesterol and [G‐3H]26‐Hydroxycholesterol , 2007 .

[2]  B. Angelin,et al.  Bile acid synthesis in humans has a rapid diurnal variation that is asynchronous with cholesterol synthesis. , 2005, Gastroenterology.

[3]  E. De Fabiani,et al.  A minimally invasive technique for the evaluation of the regulatory steps of the two major pathways of bile acid synthesis. , 2005, Clinica chimica acta; international journal of clinical chemistry.

[4]  D. Russell.  The enzymes, regulation, and genetics of bile acid synthesis. , 2003, Annual review of biochemistry.

[5]  G. Terraneo,et al.  Synthesis of deuterated isotopomers of 7α- and (25R,S)-26-hydroxycholesterol, internal standards for in vivo determination of the two biosynthetic pathways of bile acids , 2003, Steroids.

[6]  J. Talwalkar,et al.  Primary biliary cirrhosis , 2003, The Lancet.

[7]  D. Russell,et al.  Cholic acid mediates negative feedback regulation of bile acid synthesis in mice. , 2002, The Journal of clinical investigation.

[8]  P. Invernizzi,et al.  Hyperlipidaemic state and cardiovascular risk in primary biliary cirrhosis , 2002, Gut.

[9]  B. Angelin,et al.  Differences in the Regulation of the Classical and the Alternative Pathway for Bile Acid Synthesis in Human Liver , 2002, The Journal of Biological Chemistry.

[10]  I. Björkhem,et al.  Oxysterols: Friends, Foes, or Just Fellow Passengers? , 2002, Arteriosclerosis, thrombosis, and vascular biology.

[11]  N. Javitt.  25R,26-Hydroxycholesterol revisited: synthesis, metabolism, and biologic roles. , 2002, Journal of lipid research.

[12]  N. Mitro,et al.  The negative effects of bile acids and tumor necrosis factor-alpha on the transcription of cholesterol 7alpha-hydroxylase gene (CYP7A1) converge to hepatic nuclear factor-4: a novel mechanism of feedback regulation of bile acid synthesis mediated by nuclear receptors. , 2001, The Journal of biological chemistry.

[13]  S. Ferrari,et al.  Suppression of bile acid synthesis, but not of hepatic cholesterol 7α‐hydroxylase expression, by obstructive cholestasis in humans , 2001, Hepatology.

[14]  L. Moore,et al.  A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis. , 2000, Molecular cell.

[15]  T. A. Kerr,et al.  Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors. , 2000, Molecular cell.

[16]  N. Javitt,et al.  27-hydroxycholesterol: production rates in normal human subjects. , 1999, Journal of lipid research.

[17]  J M Guileyardo,et al.  cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain. , 1999, Proceedings of the National Academy of Sciences of the United States of America.

[18]  D. Russell,et al.  Nuclear Orphan Receptors Control Cholesterol Catabolism , 1999, Cell.

[19]  R. Stravitz,et al.  Regulation of bile acid biosynthesis. , 1999, Gastroenterology clinics of North America.

[20]  D. Russell,et al.  cDNA Cloning of Mouse and Human Cholesterol 25-Hydroxylases, Polytopic Membrane Proteins That Synthesize a Potent Oxysterol Regulator of Lipid Metabolism* , 1998, The Journal of Biological Chemistry.

[21]  M. Petroni,et al.  Serum 27-hydroxycholesterol in patients with primary biliary cirrhosis suggests alteration of cholesterol catabolism to bile acids via the acidic pathway. , 1998, Journal of lipid research.

[22]  M. Waterman,et al.  Activities of Recombinant Human Cytochrome P450c27 (CYP27) Which Produce Intermediates of Alternative Bile Acid Biosynthetic Pathways* , 1998, The Journal of Biological Chemistry.

[23]  R. Stravitz,et al.  Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat. , 1997, Gastroenterology.

[24]  I. Björkhem,et al.  Elimination of Cholesterol in Macrophages and Endothelial Cells by the Sterol 27-Hydroxylase Mechanism , 1997, The Journal of Biological Chemistry.

[25]  O. Andersson,et al.  Importance of a novel oxidative mechanism for elimination of intracellular cholesterol in humans. , 1996, Arteriosclerosis, thrombosis, and vascular biology.

[26]  幸三 林.  Cholesterol 7α - hydroxylase , 1995 .

[27]  V. Meiner,et al.  Frameshift and splice-junction mutations in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis in Jews or Moroccan origin. , 1993, The Journal of clinical investigation.

[28]  D. Russell,et al.  Characterization of human sterol 27-hydroxylase. A mitochondrial cytochrome P-450 that catalyzes multiple oxidation reaction in bile acid biosynthesis. , 1991, The Journal of biological chemistry.

[29]  Douglas G. Altman,et al.  Practical statistics for medical research , 1990 .

[30]  J. Sjövall,et al.  Concentrations of cholestenoic acids in plasma from patients with liver disease. , 1989, Journal of lipid research.

[31]  K. Einarsson,et al.  Bile acid synthesis in humans: regulation of hepatic microsomal cholesterol 7 alpha-hydroxylase activity. , 1989, Gastroenterology.

[32]  E. Stange,et al.  Role of primary and secondary bile acids as feedback inhibitors of bile acid synthesis in the rat in vivo. , 1989, The Journal of clinical investigation.

[33]  D. Levitt,et al.  Regulation of bile acid synthesis in man. Presence of a diurnal rhythm. , 1983, The Journal of clinical investigation.

[34]  F. H. Field,et al.  Cholest‐5‐ene‐3β,26‐diol: Synthesis and biomedical use of a deuterated compound , 1982 .

[35]  K. Mitropoulos,et al.  Cholesterol 7 alpha-hydroxylase. , 1977, Journal of lipid research.

[36]  M. M. Bradford.  A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. , 1976, Analytical biochemistry.

[37]  K. Boberg,et al.  Inborn errors in bile acid biosynthesis and storage of sterols other than cholesterol , 2001 .