Quantifying the role of oxygen pressure in tissue function.

it has been suggested that oxygen had reached significant levels in the earth's oceans as early as 2.5 billion years ago and has rapidly increased to near current levels about 50 million years later ([6][1]). The appearance of oxygen dramatically changed the chemical composition of the oceans and

[1]  L. C. Clark Intravascular polarographic and potentiometric electrodes for the study of circulation. , 1960, Transactions - American Society for Artificial Internal Organs.

[2]  B Chance,et al.  A sensitifve bacterial luminescence probe for O2 in biochemical systems. , 1972, Biochimica et biophysica acta.

[3]  Whalen Wj Intracellular PO2 in heart and skeletal muscle. , 1971 .

[4]  J. Dunn,et al.  The effects of anesthesia on cerebral tissue oxygen tension: use of EPR oximetry to make repeated measurements. , 2003, Advances in experimental medicine and biology.

[5]  Matthew C Barker,et al.  Microvascular oxygen tension in the rat mesentery. , 2008, American journal of physiology. Heart and circulatory physiology.

[6]  A. J. Kaufman,et al.  Late Archean Biospheric Oxygenation and Atmospheric Evolution , 2007, Science.

[7]  D. Lübbers,et al.  Evaluation of PO(2) profiles to describe the oxygen pressure field within the tissue. , 2002, Comparative biochemistry and physiology. Part A, Molecular & integrative physiology.

[8]  W. Rumsey,et al.  Oxygen diffusion and mitochondrial respiration in neuroblastoma cells. , 1989, The American journal of physiology.

[9]  H. Swartz Using EPR to measure a critical but often unmeasured component of oxidative damage: oxygen. , 2004, Antioxidants & redox signaling.

[10]  Sergei A Vinogradov,et al.  Oxygen pressures in the interstitial space and their relationship to those in the blood plasma in resting skeletal muscle. , 2006, Journal of applied physiology.

[11]  Sergei A. Vinogradov,et al.  Frequency domain instrument for measuring phosphorescence lifetime distributions in heterogeneous samples , 2001 .

[12]  I. Longmuir Respiration rate of rat-liver cells at low oxygen concentrations. , 1957, The Biochemical journal.

[13]  J. Vanderkooi,et al.  An optical method for measurement of dioxygen concentration based upon quenching of phosphorescence. , 1987, The Journal of biological chemistry.

[14]  H. Degn,et al.  Measurement of steady-state values of respiration rate and oxidation levels of respiratory pigments at low oxygen tensions. A new technique. , 1971, Biochimica et biophysica acta.

[15]  P. Nair,et al.  Measurements of oxygen tension in tissues with a micro oxygen electrode. , 1973, Microvascular research.

[16]  I. Silver,et al.  The oxygen dependence of cellular energy metabolism. , 1979, Archives of biochemistry and biophysics.

[17]  B Chance,et al.  Mitochondrial function under hypoxic conditions: the steady states of cytochrome alpha+alpha3 and their relation to mitochondrial energy states. , 1974, Biochimica et biophysica acta.

[18]  M. Delivoria-Papadopoulos,et al.  Relationship of extracellular dopamine in striatum of newborn piglets to cortical oxygen pressure , 1994, Neurochemical Research.

[19]  C. Koch,et al.  Radiosensitization of hypoxic tumor cells by dodecafluoropentane: a gas-phase perfluorochemical emulsion. , 2002, Cancer research.

[20]  W. Rumsey,et al.  The oxygen dependence of mitochondrial oxidative phosphorylation measured by a new optical method for measuring oxygen concentration. , 1988, The Journal of biological chemistry.

[21]  W. Whalen Intracellular PO2 in heart and skeletal muscle. , 1971, The Physiologist.

[22]  B Chance,et al.  Pyridine Nucleotide as an Indicator of the Oxygen Requirements for Energy‐Linked Functions of Mitochondria , 1976, Circulation research.

[23]  C. Koch,et al.  Measurement of absolute oxygen levels in cells and tissues using oxygen sensors and 2-nitroimidazole EF5. , 2002, Methods in enzymology.

[24]  Stephen Lemos,et al.  A New Technique , 2004, The American journal of sports medicine.