Selenoprotein K Mediates the Proliferation, Migration, and Invasion of Human Choriocarcinoma Cells by Negatively Regulating Human Chorionic Gonadotropin Expression via ERK, p38 MAPK, and Akt Signaling Pathway

[1]  P. Hoffmann,et al.  Endoplasmic reticulum-resident selenoproteins as regulators of calcium signaling and homeostasis. , 2017, Cell calcium.

[2]  I. Braakman,et al.  Co‐ and Post‐Translational Protein Folding in the ER , 2016, Traffic.

[3]  H. Steinbrenner,et al.  Selenoproteins: Antioxidant selenoenzymes and beyond. , 2016, Archives of biochemistry and biophysics.

[4]  Seung-Rock Lee,et al.  Selenoprotein S-dependent Selenoprotein K Binding to p97(VCP) Protein Is Essential for Endoplasmic Reticulum-associated Degradation* , 2015, The Journal of Biological Chemistry.

[5]  G. C. Wang,et al.  Overexpression of selenoprotein SelK in BGC-823 cells inhibits cell adhesion and migration , 2015, Biochemistry (Moscow).

[6]  T. Fehm,et al.  Gestational Trophoblastic Disorders: An Update in 2015 , 2015, Geburtshilfe und Frauenheilkunde.

[7]  P. Hoffmann,et al.  Selenoprotein K and protein palmitoylation. , 2015, Antioxidants & redox signaling.

[8]  S. Costantini,et al.  Evaluation of the Selenotranscriptome Expression in Two Hepatocellular Carcinoma Cell Lines , 2015, Analytical cellular pathology.

[9]  J. Guibourdenche,et al.  Review: hCGs: different sources of production, different glycoforms and functions. , 2015, Placenta.

[10]  E. Kohn,et al.  The MAPK pathway across different malignancies: A new perspective , 2014, Cancer.

[11]  O. G. Wong,et al.  Downregulation of the Gli Transcription Factors Regulator Kif7 Facilitates Cell Survival and Migration of Choriocarcinoma Cells , 2014, PloS one.

[12]  J. Charron,et al.  Essential role of the ERK/MAPK pathway in blood-placental barrier formation , 2014, Development.

[13]  Seung-Rock Lee,et al.  Pro178 and Pro183 of Selenoprotein S Are Essential Residues for Interaction with p97(VCP) during Endoplasmic Reticulum-associated Degradation* , 2014, The Journal of Biological Chemistry.

[14]  Jun Liu,et al.  Expression and purification of the membrane enzyme selenoprotein K. , 2012, Protein expression and purification.

[15]  J. Hesketh,et al.  Polymorphisms in Thioredoxin Reductase and Selenoprotein K Genes and Selenium Status Modulate Risk of Prostate Cancer , 2012, PloS one.

[16]  C. Hartmann,et al.  Glutathione peroxidase 1 activity dictates the sensitivity of glioblastoma cells to oxidative stress , 2012, Glia.

[17]  L. Cole hCG, the wonder of today's science , 2012, Reproductive Biology and Endocrinology.

[18]  S. Gygi,et al.  Selenoprotein K Binds Multiprotein Complexes and Is Involved in the Regulation of Endoplasmic Reticulum Homeostasis* , 2011, The Journal of Biological Chemistry.

[19]  Q. Wang,et al.  Selenoprotein dSelK in Drosophila elevates release of Ca2+ from endoplasmic reticulum by upregulating expression of inositol 1,4,5-tris-phosphate receptor , 2011, Biochemistry (Moscow).

[20]  Gong Yang,et al.  Overexpression of the β subunit of human chorionic gonadotropin promotes the transformation of human ovarian epithelial cells and ovarian tumorigenesis. , 2011, The American journal of pathology.

[21]  G. Lippi,et al.  Human chorionic gonadotropin in pregnancy diagnostics. , 2011, Clinica chimica acta; international journal of clinical chemistry.

[22]  M. Zeegers,et al.  Selenium for preventing cancer , 2012, The Cochrane database of systematic reviews.

[23]  D. Charnock-Jones,et al.  Regulation of AKT Phosphorylation at Ser473 and Thr308 by Endoplasmic Reticulum Stress Modulates Substrate Specificity in a Severity Dependent Manner , 2011, PloS one.

[24]  Fukun W. Hoffmann,et al.  Selenoprotein K Knockout Mice Exhibit Deficient Calcium Flux in Immune Cells and Impaired Immune Responses , 2011, The Journal of Immunology.

[25]  Kaixun Huang,et al.  SelK is a novel ER stress-regulated protein and protects HepG2 cells from ER stress agent-induced apoptosis. , 2010, Archives of biochemistry and biophysics.

[26]  V. Gladyshev,et al.  Structure-function relations, physiological roles, and evolution of mammalian ER-resident selenoproteins. , 2010, Antioxidants & redox signaling.

[27]  E. Choi,et al.  Pathological roles of MAPK signaling pathways in human diseases. , 2010, Biochimica et biophysica acta.

[28]  Wancai Yang,et al.  Transcriptional Regulation and Biological Functions of Selenium-Binding Protein 1 in Colorectal Cancer In Vitro and in Nude Mouse Xenografts , 2009, PloS one.

[29]  E. Marcotte,et al.  Global signatures of protein and mRNA expression levelsw , 2009 .

[30]  Nathaniel Rothman,et al.  Lead Exposure, Polymorphisms in Genes Related to Oxidative Stress, and Risk of Adult Brain Tumors , 2009, Cancer Epidemiology Biomarkers & Prevention.

[31]  J. Crowley,et al.  Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT). , 2009, JAMA.

[32]  I. Shih Gestational trophoblastic neoplasia--pathogenesis and potential therapeutic targets. , 2007, The Lancet. Oncology.

[33]  Kum Kum Khanna,et al.  From selenium to selenoproteins: synthesis, identity, and their role in human health. , 2007, Antioxidants & redox signaling.

[34]  Junjun Yang,et al.  Recurrent gestational trophoblastic tumor: management and risk factors for recurrence. , 2006, Gynecologic oncology.

[35]  Xiaozhong Peng,et al.  Identification and characterization of selenoprotein K: An antioxidant in cardiomyocytes , 2006, FEBS letters.

[36]  R. Berkowitz,et al.  Gestational trophoblastic diseases: 3. Human chorionic gonadotropin-free beta-subunit, a reliable marker of placental site trophoblastic tumors. , 2006, Gynecologic oncology.

[37]  J. Connolly,et al.  A Novel Human Cancer Vaccine Elicits Cellular Responses to the Tumor-Associated Antigen, Human Chorionic Gonadotropin β , 2004, Clinical Cancer Research.

[38]  J. Harney,et al.  Antioxidant function of a novel selenoprotein in Drosophila melanogaster , 2003, Genes to cells : devoted to molecular & cellular mechanisms.

[39]  A. Cheung Pathology of gestational trophoblastic diseases. , 2003, Best practice & research. Clinical obstetrics & gynaecology.

[40]  R. Guigó,et al.  Characterization of Mammalian Selenoproteomes , 2003, Science.

[41]  Yoshiro Saito,et al.  Characterization of selenoprotein P as a selenium supply protein. , 2002, European journal of biochemistry.

[42]  R. Berkowitz,et al.  Gestational Trophoblastic Disease , 1998, Clinical obstetrics and gynecology.

[43]  R. Ruddon,et al.  Protein folding in the endoplasmic reticulum: Lessons from the human chorionic gonadotropin β subunit , 1996, Protein science : a publication of the Protein Society.

[44]  J. Lewis Diagnosis and management of gestational trophoblastic disease , 1993, Cancer.

[45]  R. Shamberger,et al.  Possible protective effect of selenium against human cancer. , 1969, Canadian Medical Association journal.

[46]  M. Landriscina,et al.  The Role of Human Chorionic Gonadotropin as Tumor Marker: Biochemical and Clinical Aspects. , 2015, Advances in experimental medicine and biology.

[47]  R. Berkowitz,et al.  Current advances in the management of gestational trophoblastic disease. , 2013, Gynecologic oncology.

[48]  S. Ozalp,et al.  Gestational trophoblastic diseases in Turkey. , 2013, The Journal of reproductive medicine.

[49]  G. Schrauzer,et al.  Cancer mortality correlation studies--III: statistical associations with dietary selenium intakes. , 1977, Bioinorganic chemistry.