Transforming Growth Factor-β Receptors and Signal Transduction

[1]  C. Heldin,et al.  Identification of Smad2, a Human Mad-related Protein in the Transforming Growth Factor β Signaling Pathway* , 1997, The Journal of Biological Chemistry.

[2]  K. Miyazono,et al.  Phosphorylation of Ser165 in TGF‐beta type I receptor modulates TGF‐beta1‐induced cellular responses. , 1996 .

[3]  J. Massagué,et al.  Partnership between DPC4 and SMAD proteins in TGF-β signalling pathways , 1996, Nature.

[4]  R. Derynck,et al.  Intracellular signalling: The Mad way to do it , 1996, Current Biology.

[5]  R. Derynck,et al.  Receptor-associated Mad homologues synergize as effectors of the TGF-β response , 1996, Nature.

[6]  H. Lodish,et al.  Signaling by chimeric erythropoietin‐TGF‐beta receptors: homodimerization of the cytoplasmic domain of the type I TGF‐beta receptor and heterodimerization with the type II receptor are both required for intracellular signal transduction. , 1996, The EMBO journal.

[7]  Irene L Andrulis,et al.  MADR2 Maps to 18q21 and Encodes a TGFβ–Regulated MAD–Related Protein That Is Functionally Mutated in Colorectal Carcinoma , 1996, Cell.

[8]  J. Baker,et al.  A novel mesoderm inducer, Madr2, functions in the activin signal transduction pathway. , 1996, Genes & development.

[9]  H. Lodish,et al.  A dominant inhibitory mutant of the type II transforming growth factor beta receptor in the malignant progression of a cutaneous T-cell lymphoma , 1996, Molecular and cellular biology.

[10]  J. Massagué TGFβ Signaling: Receptors, Transducers, and Mad Proteins , 1996, Cell.

[11]  J. Massagué,et al.  A human Mad protein acting as a BMP-regulated transcriptional activator , 1996, Nature.

[12]  P. Hoodless,et al.  MADR1, a MAD-Related Protein That Functions in BMP2 Signaling Pathways , 1996, Cell.

[13]  J. Graff,et al.  Xenopus Mad Proteins Transduce Distinct Subsets of Signals for the TGFβ Superfamily , 1996, Cell.

[14]  K. Miyazono,et al.  Signaling via hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. , 1996, Current opinion in cell biology.

[15]  Scott E. Kern,et al.  DPC4, A Candidate Tumor Suppressor Gene at Human Chromosome 18q21.1 , 1996, Science.

[16]  J. Massagué,et al.  Complementation between kinase‐defective and activation‐defective TGF‐beta receptors reveals a novel form of receptor cooperativity essential for signaling. , 1996, The EMBO journal.

[17]  Chung Lee,et al.  Genetic change in transforming growth factor β (TGF-β) receptor type I gene correlates with insensitivity to TGF-β1 in human prostate cancer cells , 1996 .

[18]  K. Kinzler,et al.  Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability. , 1995, Science.

[19]  J. Massagué,et al.  GS domain mutations that constitutively activate T beta R‐I, the downstream signaling component in the TGF‐beta receptor complex. , 1995, The EMBO journal.

[20]  K. Miyazono,et al.  Formation of hetero-oligomeric complexes of type I and type II receptors for transforming growth factor-beta. , 1994, The Journal of biological chemistry.

[21]  Jeffrey L. Wrana,et al.  Mechanism of activation of the TGF-β receptor , 1994, Nature.

[22]  D. Kingsley,et al.  The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. , 1994, Genes & development.

[23]  R Wieser,et al.  Signaling activity of transforming growth factor beta type II receptors lacking specific domains in the cytoplasmic region , 1993, Molecular and cellular biology.