Humanin detected in skeletal muscles of MELAS patients: a possible new therapeutic agent

[1]  S. Ueno,et al.  Humanin improves impaired metabolic activity and prolongs survival of serum-deprived human lymphocytes , 2003, Molecular and Cellular Biochemistry.

[2]  John Calvin Reed,et al.  Humanin peptide suppresses apoptosis by interfering with Bax activation , 2003, Nature.

[3]  I. Nishimoto,et al.  Death and survival of neuronal cells exposed to Alzheimer's insults , 2002, Journal of neuroscience research.

[4]  S. Kirchhoff,et al.  Cytosolic Heat Shock Protein 60, Apoptosis, and Myocardial Injury , 2002, Circulation.

[5]  I. Nishimoto,et al.  Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults , 2002, Neuroscience Letters.

[6]  S. Kariya,et al.  Humanin inhibits cell death of serum-deprived PC12h cells , 2002, Neuroreport.

[7]  M. Nakagawa,et al.  Apoptosis is suspended in muscle of mitochondrial encephalomyopathies , 2002, Acta Neuropathologica.

[8]  A. Yu,et al.  Bcl-2, Bcl-x, and Bax expression by immunohistochemistry in inclusion body myositis: a study of 27 cases. , 2001, Archives of pathology & laboratory medicine.

[9]  G. Sobue,et al.  A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Aβ , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[10]  I. Nishimoto,et al.  Mechanisms of neuroprotection by a novel rescue factor humanin from Swedish mutant amyloid precursor protein. , 2001, Biochemical and biophysical research communications.

[11]  B. Allard,et al.  Elevated subsarcolemmal Ca2+ in mdx mouse skeletal muscle fibers detected with Ca2+-activated K+ channels. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[12]  D. Wallace.  Mitochondrial diseases in man and mouse. , 1999, Science.

[13]  K. Majamaa,et al.  Epidemiology of A3243G, the mutation for mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes: prevalence of the mutation in an adult population. , 1998, American journal of human genetics.

[14]  Yi-Te Hsu,et al.  Movement of Bax from the Cytosol to Mitochondria during Apoptosis , 1997, The Journal of cell biology.

[15]  E. Stopa,et al.  Adult-onset MELAS. Evidence for involvement of neurons as well as cerebral vasculature in strokelike episodes. , 1996, Stroke.

[16]  D. Wallace,et al.  Molecular basis of mitochondrial DNA disease , 1994, Journal of bioenergetics and biomembranes.

[17]  R. Sakuta,et al.  Increased mitochondrial DNA in blood vessels and ragged‐red fibers in mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke‐like episodes (MELAS) , 1993, Annals of neurology.

[18]  S. Dimauro,et al.  The mitochondrial tRNA(Leu(UUR)) mutation in mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes (MELAS): genetic, biochemical, and morphological correlations in skeletal muscle. , 1992, American journal of human genetics.

[19]  S. Dimauro,et al.  MELAS: Clinical features, biochemistry, and molecular genetics , 1992, Annals of neurology.

[20]  E. Schon,et al.  Defects in mitochondrial protein synthesis and respiratory chain activity segregate with the tRNA(Leu(UUR)) mutation associated with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. , 1992, Molecular and cellular biology.

[21]  M. Parisi,et al.  Impairment of mitochondrial transcription termination by a point mutation associated with the MELAS subgroup of mitochondrial encephalomyopathies , 1991, Nature.

[22]  R. Sakuta,et al.  Vascular involvement in mitochondrial myopathy , 1989, Annals of neurology.

[23]  M. Nishikimi,et al.  Deficiency of subunits of complex I and mitochondrial encephalomyopathy , 1988, Annals of neurology.

[24]  S. Dimauro,et al.  Mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes: A distinctive clinical syndrome , 1984, Annals of neurology.

[25]  E. Davis,et al.  Reconstruction of steady state in cell-free systems. Interactions between glycolysis and mitochondrial metabolism: regulation of the redox and phosphorylation states. , 1983, Archives of biochemistry and biophysics.

[26]  D. Wilson,et al.  Regulation of cellular energy metabolism: the Crabtree effect. , 1980, Biochimica et biophysica acta.

[27]  B. Lach,et al.  Mitochondrial angiopathy in cerebral blood vessels of mitochondrial encephalomyopathy , 2004, Acta Neuropathologica.

[28]  馬木 良文.  Apoptosis-related changes in skeletal muscles of patients with mitochondrial diseases , 2002 .

[29]  S. Di Giovanni,et al.  Apoptosis in mitochondrial encephalomyopathies with mitochondrial DNA mutations: a potential pathogenic mechanism. , 2000, Brain : a journal of neurology.

[30]  ひとみ 長谷川.  Strongly succinate dehydrogenase-reactive blood vessels in muscles from patients with mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes , 1991 .