The let-7 microRNA reduces tumor growth in mouse models of lung cancer
暂无分享,去创建一个
F. Slack | A. Esquela-Kerscher | J. Weidhaas | D. Brown | J. Wiggins | A. Bader | A. Cheng | L. Patrawala | P. Trang | L. Ford | Angie Cheng | Lubna Patrawala
[1] J. Lieberman,et al. let-7 Regulates Self Renewal and Tumorigenicity of Breast Cancer Cells , 2007, Cell.
[2] Y. Ishikawa,et al. let-7 microRNA expression is reduced in bronchioloalveolar carcinoma, a non-invasive carcinoma, and is not correlated with prognosis. , 2007, Lung cancer.
[3] Imran Babar,et al. MicroRNAs as potential agents to alter resistance to cytotoxic anticancer therapy. , 2007, Cancer research.
[4] Sun-Mi Park,et al. Let-7 Prevents Early Cancer Progression by Suppressing Expression of the Embryonic Gene HMGA2 , 2007, Cell cycle.
[5] Patricia Soteropoulos,et al. MicroRNA let-7a down-regulates MYC and reverts MYC-induced growth in Burkitt lymphoma cells. , 2007, Cancer research.
[6] F. Slack,et al. The let-7 microRNA represses cell proliferation pathways in human cells. , 2007, Cancer research.
[7] Mark E. Davis,et al. Effect of siRNA nuclease stability on the in vitro and in vivo kinetics of siRNA‐mediated gene silencing , 2007, Biotechnology and bioengineering.
[8] Anindya Dutta,et al. The tumor suppressor microRNA let-7 represses the HMGA2 oncogene. , 2007, Genes & development.
[9] T. Golub,et al. Impaired microRNA processing enhances cellular transformation and tumorigenesis , 2007, Nature Genetics.
[10] F. Slack,et al. Oncomirs — microRNAs with a role in cancer , 2006, Nature Reviews Cancer.
[11] R. Stephens,et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. , 2006, Cancer cell.
[12] C. Croce,et al. A microRNA expression signature of human solid tumors defines cancer gene targets , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[13] Mark E. Davis,et al. Insights into the kinetics of siRNA-mediated gene silencing from live-cell and live-animal bioluminescent imaging , 2006, Nucleic acids research.
[14] F. Slack,et al. Reciprocal expression of lin‐41 and the microRNAs let‐7 and mir‐125 during mouse embryogenesis , 2005, Developmental dynamics : an official publication of the American Association of Anatomists.
[15] K. Kelnar,et al. High-throughput RNAi screening in vitro: from cell lines to primary cells. , 2005, RNA.
[16] F. Slack,et al. RAS Is Regulated by the let-7 MicroRNA Family , 2005, Cell.
[17] Y. Yatabe,et al. Reduced Expression of the let-7 MicroRNAs in Human Lung Cancers in Association with Shortened Postoperative Survival , 2004, Cancer Research.
[18] C. Croce,et al. Human microRNA genes are frequently located at fragile sites and genomic regions involved in cancers. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[19] M. Barbacid,et al. RAS oncogenes: the first 30 years , 2003, Nature Reviews Cancer.
[20] D. Weil,et al. Targeting the kinesin Eg5 to monitor siRNA transfection in mammalian cells. , 2002, BioTechniques.
[21] T. Jacks,et al. Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. , 2001, Genes & development.
[22] R. Kucherlapati,et al. K-ras is an essential gene in the mouse with partial functional overlap with N-ras. , 1997, Genes & development.
[23] J. Minna,et al. Molecular genetics of lung cancer. , 1988, Annual review of medicine.
[24] J. Hornaday,et al. Cancer Facts & Figures 2004 , 2004 .
[25] David P. Bartel,et al. Supporting Online Material Materials and Methods Fig. S1 Tables S1 and S2 References Database S1 Disrupting the Pairing between Let-7 and Hmga2 Enhances Oncogenic Transformation , 2022 .