Morphologic cerebral cortical asymmetry in male and female rats

Abstract Our results indicate that specific regions in the right cerebral cortex of the young adult male rat are thicker than the corresponding regions on the left. The differences attain statistical significance in areas 17, 18a, and 39. In contrast, in the young adult female, specific regions in the left cortex are uniformly thicker than the right, though the differences are not statistically significant. However, if the female is ovariectomized at birth, by young adulthood the right-left cortical pattern is similar to that of the male.

[1]  M. Diamond,et al.  Morphological changes in the young, adult and aging rate cerebral cortex, hippocampus, and diencephalon. , 1975, Behavioral biology.

[2]  H. Hughes,et al.  Anatomical and neurobehavioral investigations concerning the thalamo‐cortical organization of the rat's visual system , 1977, The Journal of comparative neurology.

[3]  N. Geschwind,et al.  Hemispheric differences in the brains of great apes. , 1975, Brain, behavior and evolution.

[4]  W. G. Webster.  TERRITORIALITY AND THE EVOLUTION OF BRAIN ASYMMETRY * , 1977, Annals of the New York Academy of Sciences.

[5]  O. Swezy.  THE ALBINO RAT. , 1928, Science.

[6]  J A Wada,et al.  Cerebral hemispheric asymmetry in humans. Cortical speech zones in 100 adults and 100 infant brains. , 1975, Archives of neurology.

[7]  M. Diamond,et al.  Morphological changes in the cerebral cortex of rats with altered levels of ovarian hormones. , 1979, Behavioral and neural biology.

[8]  R. Doty,et al.  Survival of pattern vision after removal of striate cortex in the adult cat , 1971, The Journal of comparative neurology.

[9]  W. Krieg.  Connections of the cerebral cortex. I. The albino rat. A. Topography of the cortical areas , 1946 .

[10]  V. Denenberg,et al.  Brain and behavioral asymmetries for spatial preference in rats , 1980, Brain Research.

[11]  G. Yeni-Komshian,et al.  Anatomical study of cerebral asymmetry in the temporal lobe of humans, chimpanzees, and rhesus monkeys. , 1976, Science.

[12]  J. Crichton-Browne.  ON THE WEIGHT OF THE BRAIN AND ITS COMPONENT PARTS IN THE INSANE , 1879 .

[13]  M. Diamond,et al.  A comparison of cortical thickness in male and female rats--normal and gonadectomized, young and adult. , 1979, Behavioral and neural biology.

[14]  William F. Windle,et al.  A Nissl Method Using Buffered Solutions of Thionin , 1943 .

[15]  W. Krieg.  Connections of the cerebral cortex. I. The albino rat. B. Structure of the cortical areas , 1946, The Journal of comparative neurology.

[16]  M. Diamond.  Anatomical Brain Changes Induced by Environment , 1976 .

[17]  J. Olavarria,et al.  The effect of acute lesions of the striate cortex on the retinotopic organization of the lateral peristriate cortex in the rat , 1978, Brain Research.

[18]  P Pasik,et al.  The visual world of monkeys deprived of striate cortex: effective stimulus parameters and the importance of the accessory optic system. , 1971, Vision research.

[19]  D. L. Stewart,et al.  Effects of neonatal and adult striate lesions on visual discrimination in the rabbit. , 1974, Experimental neurology.

[20]  B. McEwen,et al.  The development of estrogen receptor systems in the rat brain and pituitary: Postnatal development , 1979, Brain Research.

[21]  V. Montero,et al.  Striate-peristriate cortico-cortical connections in the albino and gray rat. , 1973, Brain research.

[22]  N. Geschwind,et al.  Human Brain: Left-Right Asymmetries in Temporal Speech Region , 1968, Science.

[23]  F. Gilles,et al.  Left-right asymmetries of the temporal speech areas of the human fetus. , 1977, Archives of neurology.

[24]  E. Bennett,et al.  Effects of environmental enrichment and impoverishment on rat cerebral cortex. , 1972, Journal of neurobiology.