Estimation of the influence of porous nanostructured materials on blood chemistry values

Nanostructured oxides and hydroxides of iron and aluminum have been synthesized. Their influence on the hematologic and blood chemistry values is examined. The synthesized samples are found to change the hematologic values in different ways. The boehmite nanostructures produced by water oxidation of AlN/Al nanoparticles exert the greatest influence on the blood chemistry values. The obtained results are important for a general understanding of how nanostructured metal oxides interact with blood components, and can be used in the development of new hemostatic agents on the basis of micro-mesoporous metal oxides.

[1]  Zhuge Xi,et al.  Intraperitoneal injection of magnetic Fe3O4-nanoparticle induces hepatic and renal tissue injury via oxidative stress in mice , 2012, International journal of nanomedicine.

[2]  Lan Xiang,et al.  Hydrothermal preparation of boehmite nanorods by selective adsorption of sulfate. , 2008, Langmuir : the ACS journal of surfaces and colloids.

[3]  Alisa S Wolberg,et al.  Thrombin generation, fibrin clot formation and hemostasis. , 2008, Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis.

[4]  K. Ooi,et al.  Phosphate adsorption on synthetic goethite and akaganeite. , 2006, Journal of colloid and interface science.

[5]  Q. Feng,et al.  Preparation of cerium-loaded Y-zeolites for removal of organic sulfur compounds from hydrodesulfurizated gasoline and diesel oil. , 2006, Journal of colloid and interface science.

[6]  E. Gutmanas,et al.  Synthesis of core–shell AlOOH hollow nanospheres by reacting Al nanoparticles with water , 2016, Nanotechnology.

[7]  S. Psakhie,et al.  On the possibility of soft matter nanostructure formation based on mesoporous aluminum hydroxide. Prospects for biomedical applications , 2017 .

[8]  Differential binding of plasma proteins by liposomes loaded with lipophilic prodrugs of methotrexate and melphalan in the bilayer , 2014, Biochemistry (Moscow).

[9]  J. Tuček,et al.  Iron oxide nanoparticle powders with high surface area , 2012 .

[10]  D. Dhall,et al.  Effect of temperature, pH and ionic strength and composition on fibrin network structure and its development. , 1986, Thrombosis research.

[11]  S. Psakhie,et al.  From the soft matter-hard matter interface to bio-self-organization and hybrid systems , 2017 .