NMR structure determination in solution: a critique and comparison with X-ray crystallography.

PERSPECTIVES AND OVERVIEW 167 THE STRUCTURAL INTERPRETATION OF NMR DATA 1 69 The Resonance A ssignment Problem . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 170 Geometric Interpretation . . . . . . . . . . . . . . . . . . . . . . . . . . . . 173 Distance Geometry Algorithms ......... 177 Refinement of N M R Structures . . . . . . . . 180