A coordinator program in post-fracture osteoporosis management improves outcomes and saves costs.

BACKGROUND The orthopaedic unit at a university teaching hospital hired an osteoporosis coordinator to identify patients with a fragility fracture and to coordinate their education, assessment, referral, and treatment of underlying osteoporosis. We report the results of an analysis of the cost-effectiveness of the use of a coordinator (in comparison with the use of no coordinator) in avoiding future costs of subsequent hip fracture. METHODS A one-year decision-analysis model was developed. The health outcome was subsequent hip fracture; only direct hospital costs were considered. With use of patient-level data from a previously described coordinator program and data from the literature, the expected annual incidence of subsequent hip fracture was calculated, on the basis of the type of index fracture (wrist, hip, humerus, other), attribution to osteoporosis, age, and gender. The rate of patient referral, the initiation of osteoporosis treatment, and adherence to therapy were modeled to modify the expected incidence of future hip fracture in the presence of a coordinator (with use of data from the program) and in the absence of a coordinator (with use of data from the literature). Sensitivity analysis modeling techniques were used to assess variable uncertainty and to evaluate coordinator cost-effectiveness. RESULTS Deterministic cost-effectiveness analysis showed that a tertiary care center that hired an osteoporosis coordinator who manages 500 patients with fragility fractures annually could reduce the number of subsequent hip fractures from thirty-four to thirty-one in the first year, with a net hospital cost savings of C$48,950 (Canadian dollars in year-2004 values), with use of conservative assumptions. Probabilistic sensitivity analysis indicated a 90% probability that hiring a coordinator costs less than C$25,000 per hip fracture avoided. Hiring a coordinator is a cost-saving measure even when the coordinator manages as few as 350 patients annually. Greater savings are anticipated after the first year and when additional costs such as rehabilitation and dependency costs are considered. CONCLUSIONS Employment of an osteoporosis coordinator to manage outpatients and inpatients who have fragility fractures is predicted to reduce the incidence of future hip fractures and to save money (a dominant strategy). A probabilistic sensitivity analysis showed a high probability of cost-effectiveness of this intervention from the hospital cost perspective.

[1]  N. Watts Bisphosphonate treatment of osteoporosis. , 2003, Clinics in geriatric medicine.

[2]  S. Gallacher,et al.  The fracture liaison service: success of a program for the evaluation and management of patients with osteoporotic fracture , 2003, Osteoporosis International.

[3]  C. Court-Brown,et al.  Refractures in Patients at Least Forty-five Years Old: A Prospective Analysis of Twenty-two Thousand and Sixty Patients , 2002, Journal of Bone and Joint Surgery. American volume.

[4]  E. Dasbach,et al.  The Effect of Alendronate on Fracture-Related Healthcare Utilization and Costs: The Fracture Intervention Trial , 2001, Osteoporosis International.

[5]  D. Beaton,et al.  Effective initiation of osteoporosis diagnosis and treatment for patients with a fragility fracture in an orthopaedic environment. , 2006, The Journal of bone and joint surgery. American volume.

[6]  B. Rowe,et al.  Persistence, reproducibility, and cost-effectiveness of an intervention to improve the quality of osteoporosis care after a fracture of the wrist: results of a controlled trial , 2007, Osteoporosis International.

[7]  J. Habbema,et al.  Hip Fracture in Elderly Patients: Outcomes for Function, Quality of Life, and Type of Residence , 2001, Clinical orthopaedics and related research.

[8]  J. Harrington,et al.  Redesigning the care of fragility fracture patients to improve osteoporosis management: a health care improvement project. , 2005, Arthritis and rheumatism.

[9]  V. Pellegrini,et al.  The inpatient consultation approach to osteoporosis treatment in patients with a fracture. Is automatic consultation needed? , 2006, The Journal of bone and joint surgery. American volume.

[10]  E. E. Hajcsar,et al.  Investigation and treatment of osteoporosis in patients with fragility fractures. , 2000, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[11]  P. Jalovaara,et al.  Mortality and quality of life after trochanteric hip fracture. , 2001, Public health.

[12]  L. Giangregorio,et al.  Fragility fractures and the osteoporosis care gap: an international phenomenon. , 2006, Seminars in arthritis and rheumatism.

[13]  G. Mclauchlan,et al.  Epidemiology of fractures in 15,000 adults: the influence of age and gender. , 1998, The Journal of bone and joint surgery. British volume.

[14]  K. Carriere,et al.  Mortality and morbidity associated with osteoporosis drug treatment following hip fracture , 2003, Osteoporosis International.

[15]  D. Heinegård,et al.  Extracellular matrix in disc degeneration. , 2006, The Journal of bone and joint surgery. American volume.

[16]  Gordon Guyatt,et al.  Meta-analyses of therapies for postmenopausal osteoporosis. IX: Summary of meta-analyses of therapies for postmenopausal osteoporosis. , 2002, Endocrine reviews.

[17]  H K Genant,et al.  Effects of risedronate treatment on vertebral and nonvertebral fractures in women with postmenopausal osteoporosis: a randomized controlled trial. Vertebral Efficacy With Risedronate Therapy (VERT) Study Group. , 1999, JAMA.

[18]  Krista F. Huybrechts,et al.  The impact of compliance with osteoporosis therapy on fracture rates in actual practice , 2004, Osteoporosis International.

[19]  T A Einhorn,et al.  Fractures Attributable to Osteoporosis: Report from the National Osteoporosis Foundation , 1997, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[20]  S. Cummings,et al.  Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. , 2007, The New England journal of medicine.

[21]  G. Wood,et al.  Osteoporosis disease management in a rural health care population: hip fracture reduction and reduced costs in postmenopausal women after 5 years , 2003, Osteoporosis International.

[22]  P. Broos,et al.  Quality of Life after Hip Fracture Surgery in the Elderly , 2006, Acta chirurgica Belgica.

[23]  Steven Boonen,et al.  Once-yearly zoledronic acid for treatment of postmenopausal osteoporosis. , 2007, The New England journal of medicine.

[24]  C. Cooper,et al.  The crippling consequences of fractures and their impact on quality of life. , 1997, The American journal of medicine.

[25]  P. Hoffmeyer,et al.  An Osteoporosis Clinical Pathway for the Medical Management of Patients with Low-Trauma Fracture , 2002, Osteoporosis International.

[26]  T J Ulahannan,et al.  Decision Making in Health and Medicine: Integrating Evidence and Values , 2002 .

[27]  R. Goeree,et al.  Economic Implications of Hip Fracture: Health Service Use, Institutional Care and Cost in Canada , 2001, Osteoporosis International.

[28]  D. Beaton,et al.  Practice patterns in the diagnosis and treatment of osteoporosis after a fragility fracture: a systematic review , 2004, Osteoporosis International.

[29]  G. Hawker,et al.  The impact of a simple fracture clinic intervention in improving the diagnosis and treatment of osteoporosis in fragility fracture patients , 2003, Osteoporosis International.