Usefulness of cutaneous ultrasound in the management of Parry Romberg syndrome

Dear editor, Parry Romberg syndrome (PRS), also known as progressive hemifacial atrophy, is a rare craniofacial disorder characterized by unilateral facial atrophy affecting the skin, subcutis, muscle, and bones.1 PRS is considered a severe variant of linear morphea, sharing some features with en coup de sabre scleroderma. Diagnosis is often delayed1 and clinical monitoring is challenging. Visible changes are usually subtle, and decisions are often based on subjective impressions from the patient or physician. We would like to share our experience on the use of cutaneous highfrequency ultrasonography (HFUS) in the management of patients with PRS. A 30yearold woman presented with a 15year history of

[1]  J. Mulliken,et al.  Early Features of Progressive Hemifacial Atrophy-Clinical and Imaging Findings. , 2020, JAMA dermatology.

[2]  R. de Lucas Laguna,et al.  Cutaneous ultrasound and its utility in pediatric dermatology. Part I: Lumps, bumps, and inflammatory conditions , 2019, Pediatric dermatology.

[3]  A. Lis-Święty,et al.  An extended high‐frequency ultrasound protocol for assessing and quantifying of inflammation and fibrosis in localized scleroderma , 2019, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[4]  M. Epelman,et al.  Musculoskeletal MRI findings of juvenile localized scleroderma , 2017, Pediatric Radiology.

[5]  M. Matucci Cerinic,et al.  High frequency ultrasound can detect improvement of lesions in juvenile localized scleroderma , 2014, Modern rheumatology.

[6]  C. Claussen,et al.  Response evaluation of musculoskeletal involvement in patients with deep morphea treated with methotrexate and prednisolone: a combined MRI and clinical approach. , 2013, AJR. American journal of roentgenology.

[7]  X. Wortsman,et al.  Activity assessment in morphea using color Doppler ultrasound. , 2011, Journal of the American Academy of Dermatology.

[8]  C. Claussen,et al.  MRI findings in deep and generalized morphea (localized scleroderma). , 2008, AJR. American journal of roentgenology.