Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences

[1]  S. Miyano,et al.  Biallelic DICER1 mutations in sporadic pleuropulmonary blastoma. , 2014, Cancer research.

[2]  Gretchen M. Williams,et al.  DICER1 mutations in childhood cystic nephroma and its relationship to DICER1-renal sarcoma , 2014, Modern Pathology.

[3]  D. Huntsman,et al.  Cancer‐associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse‐strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage , 2013, The Journal of pathology.

[4]  A. Sivachenko,et al.  Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples , 2013, Nature Biotechnology.

[5]  N. André,et al.  DICER1 Mutations in embryonal rhabdomyosarcomas from children with and without familial PPB‐tumor predisposition syndrome , 2012, Pediatric blood & cancer.

[6]  Arjun Bhutkar,et al.  In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs. , 2012, RNA.

[7]  Piero Carninci,et al.  Site-specific DICER and DROSHA RNA products control the DNA damage response , 2012, Nature.

[8]  Helga Thorvaldsdóttir,et al.  Integrative Genomics Viewer (IGV): high-performance genomics data visualization and exploration , 2012, Briefings Bioinform..

[9]  L. Dehner,et al.  Embryonal rhabdomyosarcoma of the uterine cervix: a report of 14 cases and a discussion of its unusual clinicopathological associations , 2012, Modern Pathology.

[10]  Yun-Gui Yang,et al.  A Role for Small RNAs in DNA Double-Strand Break Repair , 2012, Cell.

[11]  Steven J. M. Jones,et al.  Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers. , 2012, The New England journal of medicine.

[12]  L. Borsu,et al.  Oncogene Mutation Profiling of Pediatric Solid Tumors Reveals Significant Subsets of Embryonal Rhabdomyosarcoma and Neuroblastoma with Mutated Genes in Growth Signaling Pathways , 2011, Clinical Cancer Research.

[13]  W. Foulkes,et al.  Extending the phenotypes associated with DICER1 mutations , 2011, Human mutation.

[14]  S. Pfister,et al.  Functional characterization of a BRAF insertion mutant associated with pilocytic astrocytoma , 2011, International journal of cancer.

[15]  Gretchen M. Williams,et al.  Ovarian sex cord-stromal tumors, pleuropulmonary blastoma and DICER1 mutations: a report from the International Pleuropulmonary Blastoma Registry. , 2011, Gynecologic oncology.

[16]  G. Getz,et al.  GISTIC2.0 facilitates sensitive and confident localization of the targets of focal somatic copy-number alteration in human cancers , 2011, Genome Biology.

[17]  Trevor J Pugh,et al.  Initial genome sequencing and analysis of multiple myeloma , 2011, Nature.

[18]  A. Nicholson,et al.  DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome , 2011, Journal of Medical Genetics.

[19]  W. Foulkes,et al.  DICER1 mutations in familial multinodular goiter with and without ovarian Sertoli-Leydig cell tumors. , 2011, JAMA.

[20]  Helga Thorvaldsdóttir,et al.  Integrative Genomics Viewer , 2011, Nature Biotechnology.

[21]  Mingming Jia,et al.  COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer , 2010, Nucleic Acids Res..

[22]  M. DePristo,et al.  The Genome Analysis Toolkit: a MapReduce framework for analyzing next-generation DNA sequencing data. , 2010, Genome research.

[23]  David W. Taylor,et al.  A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity , 2010, Science.

[24]  Derek Y. Chiang,et al.  The landscape of somatic copy-number alteration across human cancers , 2010, Nature.

[25]  Gretchen M. Williams,et al.  DICER1 Mutations in Familial Pleuropulmonary Blastoma , 2009, Science.

[26]  Gretchen M. Williams,et al.  Type I Pleuropulmonary Blastoma: Pathology and Biology Study of 51 Cases From the International Pleuropulmonary Blastoma Registry , 2008, The American journal of surgical pathology.

[27]  Guy Cavet,et al.  Comment on "The Consensus Coding Sequences of Human Breast and Colorectal Cancers" , 2007, Science.

[28]  P. Hou,et al.  Functional Characterization of the T1799-1801del and G1799-1816ins BRAF Mutations in Papillary Thyroid Cancer , 2007, Cell cycle.

[29]  T. Hubbard,et al.  A census of human cancer genes , 2004, Nature Reviews Cancer.

[30]  Benjamin M. Bolstad,et al.  affy - analysis of Affymetrix GeneChip data at the probe level , 2004, Bioinform..

[31]  Triona Goode,et al.  C/EBPα Arrests Cell Proliferation through Direct Inhibition of Cdk2 and Cdk4 , 2001 .

[32]  S. Henikoff,et al.  Predicting deleterious amino acid substitutions. , 2001, Genome research.

[33]  Steven A. Roberts,et al.  Mutational heterogeneity in cancer and the search for new cancer genes , 2014 .

[34]  Trevor J Pugh,et al.  Mutational heterogeneity in cancer and the search for new cancer genes , 2014 .

[35]  Claude-Alain H. Roten,et al.  Fast and accurate short read alignment with Burrows–Wheeler transform , 2009, Bioinform..

[36]  A. Welm,et al.  C/EBPalpha arrests cell proliferation through direct inhibition of Cdk2 and Cdk4. , 2001, Molecular cell.