A soft kinetic data structure for lesion border detection

Motivation: The medical imaging and image processing techniques, ranging from microscopic to macroscopic, has become one of the main components of diagnostic procedures to assist dermatologists in their medical decision-making processes. Computer-aided segmentation and border detection on dermoscopic images is one of the core components of diagnostic procedures and therapeutic interventions for skin cancer. Automated assessment tools for dermoscopic images have become an important research field mainly because of inter- and intra-observer variations in human interpretations. In this study, a novel approach—graph spanner—for automatic border detection in dermoscopic images is proposed. In this approach, a proximity graph representation of dermoscopic images in order to detect regions and borders in skin lesion is presented. Results: Graph spanner approach is examined on a set of 100 dermoscopic images whose manually drawn borders by a dermatologist are used as the ground truth. Error rates, false positives and false negatives along with true positives and true negatives are quantified by digitally comparing results with manually determined borders from a dermatologist. The results show that the highest precision and recall rates obtained to determine lesion boundaries are 100%. However, accuracy of assessment averages out at 97.72% and borders errors' mean is 2.28% for whole dataset. Contact: skockara@uca.edu

[1]  Leonidas J. Guibas,et al.  Kinetic data structures: a state of the art report , 1998 .

[2]  Randy H. Moss,et al.  A methodological approach to the classification of dermoscopy images , 2007, Comput. Medical Imaging Graph..

[3]  M. Martini An Atlas of Surface Microscopy of Pigmented Skin Lesions: Dermoscopy, 2nd ed , 2004 .

[4]  M. Binder,et al.  Epiluminescence microscopy. A useful tool for the diagnosis of pigmented skin lesions for formally trained dermatologists. , 1995, Archives of dermatology.

[5]  M. Stella Atkins,et al.  Dermascopic hair disocclusion using inpainting , 2008, SPIE Medical Imaging.

[6]  T Lee,et al.  Dullrazor®: A software approach to hair removal from images , 1997, Comput. Biol. Medicine.

[7]  C R Dyer,et al.  Techniques for a structural analysis of dermatoscopic imagery. , 1998, Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society.

[8]  Masafumi Hagiwara,et al.  Quantitative assessment of tumour extraction from dermoscopy images and evaluation of computer-based extraction methods for an automatic melanoma diagnostic system , 2006, Melanoma research.

[9]  S. Menzies An atlas of surface microscopy of pigmented skin lesions , 1996 .

[10]  Jitendra Malik,et al.  Image and video segmentation: the normalized cut framework , 1998, Proceedings 1998 International Conference on Image Processing. ICIP98 (Cat. No.98CB36269).

[11]  P. Morton,et al.  Progress in Biomedical Optics and Imaging , 2003 .

[12]  Gerald Schaefer,et al.  Lesion border detection in dermoscopy images , 2009, Comput. Medical Imaging Graph..

[13]  Jun Zhang,et al.  Segmentation of dermatoscopic images by stabilized inverse diffusion equations , 1998, Proceedings 1998 International Conference on Image Processing. ICIP98 (Cat. No.98CB36269).

[14]  K Wolff,et al.  Statistical evaluation of epiluminescence microscopy criteria for melanocytic pigmented skin lesions. , 1993, Journal of the American Academy of Dermatology.

[15]  Constantine Butakoff,et al.  Independent Histogram Pursuit for Segmentation of Skin Lesions , 2008, IEEE Transactions on Biomedical Engineering.

[16]  Patrick Hébert,et al.  Median Filtering in Constant Time , 2007, IEEE Transactions on Image Processing.

[17]  Jitendra Malik,et al.  Normalized cuts and image segmentation , 1997, Proceedings of IEEE Computer Society Conference on Computer Vision and Pattern Recognition.

[18]  W. Stoecker,et al.  Unsupervised border detection in dermoscopy images , 2007, Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging.

[19]  James M. Rehg,et al.  Feature-preserving artifact removal from dermoscopy images , 2008, SPIE Medical Imaging.

[20]  Gerald Schaefer,et al.  Skin lesion segmentation using co-operative neural network edge detection and colour normalisation , 2009, 2009 9th International Conference on Information Technology and Applications in Biomedicine.

[21]  Rita Cucchiara,et al.  Comparison of color clustering algorithms for segmentation of dermatological images , 2006, SPIE Medical Imaging.

[22]  Leonidas J. Guibas,et al.  Deformable spanners and applications , 2004, SCG '04.

[23]  M. Binder,et al.  Epiluminescence microscopy. A useful tool for the diagnosis of pigmented skin lesions for formally trained dermatologists. , 1995, Archives of dermatology.

[24]  Leonidas J. Guibas,et al.  Data structures for mobile data , 1997, SODA '97.

[25]  Gerald Schaefer,et al.  Skin lesion extraction in dermoscopic images based on colour enhancement and iterative segmentation , 2009, 2009 16th IEEE International Conference on Image Processing (ICIP).

[26]  Haim Kaplan,et al.  Kinetic and dynamic data structures for convex hulls and upper envelopes , 2007, Comput. Geom..

[27]  Leonidas J. Guibas,et al.  Exploring Protein Folding Trajectories Using Geometric Spanners , 2004, Pacific Symposium on Biocomputing.

[28]  A. Jemal,et al.  Cancer Statistics, 2008 , 2008, CA: a cancer journal for clinicians.

[29]  P. Schmid Segmentation of digitized dermatoscopic images by two-dimensional color clustering , 1999, IEEE Transactions on Medical Imaging.

[30]  Artur Czumaj,et al.  Soft kinetic data structures , 2001, SODA '01.

[31]  Joost van de Weijer,et al.  Fast Anisotropic Gauss Filtering , 2002, ECCV.

[32]  William K. Pratt,et al.  Digital Image Processing: PIKS Inside , 2001 .

[33]  Milan Sonka,et al.  Image Processing, Analysis and Machine Vision , 1993, Springer US.