High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids.
暂无分享,去创建一个
Michael J Cima | Orn Almarsson | Matthew L Peterson | M. Cima | M. Peterson | S. Morissette | A. Lemmo | Steve Ellis | O. Almarsson | C. Gardner | J. Remenar | Anthony V Lemmo | Julius F Remenar | Sherry L Morissette | Michael J Read | Steve Ellis | Colin R Gardner | Michael J. Read
[1] F. Leusen. Crystal Structure Prediction of Diastereomeric Salts: A Step toward Rationalization of Racemate Resolution , 2003 .
[2] G A Stephenson,et al. Characterization of the solid state: quantitative issues. , 2001, Advanced drug delivery reviews.
[3] R. Davey,et al. From Molecules to Crystallizers , 2001 .
[4] Jonathan Harr,et al. A Civil Action , 1995 .
[5] Gordon J. T. Tiddy,et al. Crystal engineering – nucleation, the key step , 2002 .
[6] D. Allan,et al. The formation of paracetamol (acetaminophen) adducts with hydrogen-bond acceptors. , 2002, Acta crystallographica. Section B, Structural science.
[7] Jack,et al. Disappearing Polymorphs , 2001 .
[8] W. Tong,et al. In situ salt screening--a useful technique for discovery support and preformulation studies. , 1998, Pharmaceutical development and technology.
[9] L. Blair. A prediction. , 1995, Hospitals & health networks.
[10] Kenneth R. Morris,et al. An integrated approach to the selection of optimal salt form for a new drug candidate , 1994 .
[11] D. Bugay. Characterization of the solid-state: spectroscopic techniques. , 2001, Advanced drug delivery reviews.
[12] J. Guillory. GENERATION OF POLYMORPHS, HYDRATES, SOLVATES, AND AMORPHOUS SOLIDS , 1999 .
[13] Matt Peterson,et al. Application of high throughput technologies to drug substance and drug product development , 2004, Comput. Chem. Eng..
[14] Stephen Byrn,et al. Pharmaceutical Solids: A Strategic Approach to Regulatory Considerations , 1995, Pharmaceutical Research.
[15] A. Myerson,et al. Effect of Additives on the Transformation Behavior of l-Phenylalanine in Aqueous Solution , 2001 .
[16] W. Beckmann,et al. Crystallisation of the Stable Polymorph of Hydroxytriendione: Seeding Process and Effects of Purity , 2001 .
[17] S. Byrn. Solid state chemistry of drugs , 1982 .
[18] A. Matzger,et al. The use of polymer heteronuclei for crystalline polymorph selection. , 2002, Journal of the American Chemical Society.
[19] C. A. Mitchell,et al. Selective nucleation and discovery of organic polymorphs through epitaxy with single crystal substrates. , 2001, Journal of the American Chemical Society.
[20] Lian Yu. Color Changes Caused by Conformational Polymorphism: Optical-Crystallography, Single-Crystal Spectroscopy, and Computational Chemistry , 2002 .
[21] L. Leiserowitz,et al. The effect of solvent on crystal growth and morphology , 2001 .
[22] S M Berge,et al. Pharmaceutical salts. , 1977, Journal of pharmaceutical sciences.
[23] R. J. Roberts,et al. Potential polymorphs of aspirin , 1999, J. Comput. Chem..
[24] T. Threlfall. Crystallisation of Polymorphs: Thermodynamic Insight into the Role of Solvent , 2000 .
[25] J. Bauer,et al. Ritonavir: An Extraordinary Example of Conformational Polymorphism , 2001, Pharmaceutical Research.
[26] Thomas D.Y. Chung,et al. Assay Miniaturization for Ultra-High Throughput Screening of Combinatorial and Discrete Compound Libraries: A 9600-Well (0.2 Microliter) Assay System , 1998 .
[27] J. McMahon,et al. Crystal engineering of the composition of pharmaceutical phases. , 2003, Chemical communications.
[28] Crystalline Solids , 2018, Statistical Thermodynamics.
[29] David J.W. Grant,et al. Solid-state pharmaceutical chemistry , 1994 .
[31] H. Brittain. Polymorphism in Pharmaceutical Solids , 1999 .
[32] J. Anwar,et al. Crystallization of polymorphs : the effect of solvent , 1993 .
[33] P Verwer,et al. A test of crystal structure prediction of small organic molecules. , 2000, Acta crystallographica. Section B, Structural science.
[34] J. Dunitz. Are crystal structures predictable? , 2003, Chemical communications.
[35] C. A. Mitchell,et al. Thermochemistry and Conformational Polymorphism of a Hexamorphic Crystal System , 2000 .
[36] R. Davey,et al. Disappearing polymorphs and the role of reaction by-products: the case of sulphathiazole , 1998 .
[37] L. Addadi,et al. Molecular Recognition at Crystal Interfaces , 1991, Science.
[38] P. L. Gould,et al. Salt selection for basic drugs , 1986 .
[39] Sarah L Price,et al. Crystal structure prediction of small organic molecules: a second blind test. , 2002, Acta crystallographica. Section B, Structural science.
[40] Orn Almarsson,et al. High-Throughput Surveys of Crystal Form Diversity of Highly Polymorphic Pharmaceutical Compounds , 2003 .
[41] C. Lipinski. Drug-like properties and the causes of poor solubility and poor permeability. , 2000, Journal of pharmacological and toxicological methods.
[42] A. Myerson,et al. Polarization switching of crystal structure in the nonphotochemical light-induced nucleation of supersaturated aqueous glycine solutions. , 2002, Physical review letters.
[43] J. Bernstein. Crystal growth, polymorphism and structure-property relationships in organic crystals , 1993 .
[44] A. Gavezzotti,et al. Ten years of experience in polymorph prediction: what next? , 2002 .
[45] Jeffrey S. Tan,et al. Capillary Precipitation of a Highly Polymorphic Organic Compound , 2003 .
[46] E. Landau,et al. 'Tailormade' auxiliaries for nucleation, growth and dissolution of organic crystals , 1986 .
[47] Paul E. Shaw,et al. Iterative high-throughput polymorphism studies on acetaminophen and an experimentally derived structure for form III. , 2002, Journal of the American Chemical Society.
[48] W. Ostwald. Studien über die Bildung und Umwandlung fester Körper , 1897 .
[49] George Zhou,et al. Process Optimization of a Complex Pharmaceutical Polymorphic System via In Situ Raman Spectroscopy , 2002 .
[50] Richard J. Bastin,et al. Salt Selection and Optimisation Procedures for Pharmaceutical New Chemical Entities , 2000 .
[51] Thomas Earnest,et al. Automation of X-ray crystallography , 2000, Nature Structural Biology.
[52] S. Tavener,et al. Sulfathiazole polymorphism studied by magic-angle spinning NMR. , 1999, Journal of pharmaceutical sciences.
[53] D. Fox. Physics and Chemistry of the Organic Solid State , 1963 .
[54] P. Cong,et al. High throughput screening techniques for pre-formulation: salt selection and polymorph studies , 2002 .
[55] A. Gavezzotti,et al. Are Crystal Structures Predictable , 1994 .
[56] M. Kaufman,et al. Investigation of the polymorphism of the angiotensin II antagonist agent MK-996. , 1999, Pharmaceutical development and technology.
[57] R. Howie,et al. Crystal growth , 1982, Nature.
[58] B. A. Garetz,et al. Nonphotochemical, laser-induced nucleation of supersaturated aqueous glycine produces unexpected γ-polymorph , 2001 .
[59] P. York,et al. Polymorph Control of Sulfathiazole in Supercritical CO2 , 2001, Pharmaceutical Research.
[60] Lance Stewart,et al. High-throughput crystallization and structure determination in drug discovery. , 2002, Drug discovery today.
[61] Phase transition and heterogeneous/epitaxial nucleation of hydrated and anhydrous theophylline crystals , 1992 .
[62] M. Peruggia. Experiments with Mixtures: Designs, Models, and the Analysis of Mixture Data , 2003 .
[63] Z. Zhang,et al. Crystal growth. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[64] M. Caira,et al. Crystalline Polymorphism of Organic Compounds , 1998 .
[65] G. Day,et al. The prediction, morphology, and mechanical properties of the polymorphs of paracetamol. , 2001, Journal of the American Chemical Society.
[66] N. Rodríguez-Hornedo,et al. Significance of controlling crystallization mechanisms and kinetics in pharmaceutical systems. , 1999, Journal of pharmaceutical sciences.
[67] I. Weissbuch,et al. Toward Stereochemical Control, Monitoring, and Understanding of Crystal Nucleation , 2003 .
[68] S. Chemburkar,et al. Dealing with the Impact of Ritonavir Polymorphs on the Late Stages of Bulk Drug Process Development , 2000 .
[69] R. Davey,et al. Crystal Polymorphism as a Probe for Molecular Self-Assembly during Nucleation from solutions: The Case of 2,6 - Dihydroxybenzoic Acid. , 2001 .
[70] Miss A.O. Penney. (b) , 1974, The New Yale Book of Quotations.
[71] Orn Almarsson,et al. Crystal engineering of novel cocrystals of a triazole drug with 1,4-dicarboxylic acids. , 2003, Journal of the American Chemical Society.
[72] K. Morris,et al. Stabilization of a Metastable Polymorph of 4-Methyl-2-nitroacetanilide by Isomorphic Additives , 2001 .
[73] B. Shekunov,et al. Formation of composite crystals by precipitation in supercritical CO2 , 2003 .
[74] I. Hunter,et al. Laser Raman spectroscopic analysis of polymorphic forms in microliter fluid volumes. , 2003, Journal of pharmaceutical sciences.
[75] S. Childs,et al. Polymorph Generation in Capillary Spaces: The Preparation and Structural Analysis of a Metastable Polymorph of Nabumetone , 2002 .
[76] R. Docherty,et al. Polymorphism in Molecular Crystals: Stabilization of a Metastable Form by Conformational Mimicry , 1997 .
[77] J. Cornell. Experiments with Mixtures: Designs, Models and the Analysis of Mixture Data , 1982 .
[78] Young,et al. Nonphotochemical, Polarization-Dependent, Laser-Induced Nucleation in Supersaturated Aqueous Urea Solutions. , 1996, Physical review letters.
[80] Joel Bernstein,et al. Polymorphism in Molecular Crystals , 2002 .
[81] A. Matzger,et al. Form IV of carbamazepine. , 2002, Journal of pharmaceutical sciences.
[82] Michael J. Cima,et al. Elucidation of crystal form diversity of the HIV protease inhibitor ritonavir by high-throughput crystallization , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[83] R. S. Payne,et al. Crystal chemistry and solvent effects in polymorphic systems Sulfathiazole , 1998 .