Cell clones and pattern formation: On the lineage of photoreceptor cells in the compound eye ofDrosophila

SummaryThe generalogical relationships of photoreceptor cells within the compound eye ofDrosophila have been studied using cell labelling, with either3H-thymidine or recessive mutations, during the third larval stage. It has been found that photoreceptor and secondary pigment cells arise from different precursor cells. Under the present experimental conditions, precursors of receptor cells give rise to about 8 elements which differentiate as R cells of two different groups. One of the cells differentiates as R7 and the remaining as any one of the R1 to R6. The last cells behave initially as equivalent, and can differentiate within the same or within different, but neighbouring, ommatidia. The class of R1 to R6 cell in which each one of these elements differentiates, seems to depend on the time of its origin. The implications of these findings for the formation of the ommatidial pattern are discussed.

[1]  A. Garcı́a-Bellido,et al.  Parameters of the wing imaginal disc development of Drosophila melanogaster. , 1971, Developmental biology.

[2]  D. Lindsley,et al.  Genetic variations of Drosophila melanogaster , 1967 .

[3]  S. Benzer,et al.  From the gene to behavior. , 1971, JAMA.

[4]  J. Campos-Ortega,et al.  The development of ommatidial patterning in metamorphosed eye imaginal discs implants ofDrosophila melanogaster , 1976, Wilhelm Roux's archives of developmental biology.

[5]  S. Benzer.  Genetic dissection of behavior. , 1973, Scientific American.

[6]  C. Stern,et al.  On cell lethals in Drosophila. , 1971, Proceedings of the National Academy of Sciences of the United States of America.

[7]  G. Morata,et al.  Developmental compartmentalisation of the wing disk of Drosophila. , 1973, Nature: New biology.

[8]  J. Campos-Ortega,et al.  Cell clones and pattern formation: Genetic eye mosaics inDrosophila melanogaster , 1976, Wilhelm Roux's archives of developmental biology.

[9]  D. Fristrom.  Cellular degeneration in the production of some mutant phenotypes in Drosophila melanogaster , 2004, Molecular and General Genetics MGG.

[10]  S. Benzer,et al.  Development of the Drosophila retina, a neurocrystalline lattice. , 1976, Developmental biology.

[11]  F. Crick,et al.  Compartments and polyclones in insect development. , 1975, Science.

[12]  K. Kirschfeld.  DAS NEURALE SUPERPOSITIONSAUGE , 1973 .

[13]  G. Morata,et al.  Developmental compartmentalization in the dorsal mesothoracic disc of Drosophila. , 1976, Developmental biology.

[14]  O. Trujillo-Cenóz,et al.  The fine structure of the central cells in the ommatidia of dipterans. , 1967, Journal of ultrastructure research.

[15]  A. Garcı́a-Bellido.  Pattern Formation in Imaginal Disks , 1972 .

[16]  H. Becker.  Über Röntgenmosaikflecken Und Defektmutationen Am Auge Von Drosophila Und Die Entwicklungsphysiologie Des Auges , 2004, Zeitschrift für Induktive Abstammungs- und Vererbungslehre.

[17]  K. Kirschfeld.  [Neural superposition eye]. , 1973, Fortschritte der Zoologie.

[18]  W. Harris,et al.  Genetic dissection of the photoreceptor system in the compound eye of Drosophila melanogaster , 1976, The Journal of physiology.

[19]  H. Becker.  [Roentgen mosaic spots & defective mutations at the eye of Drosophila & the evolutive physiology of the eye]. , 1957, Zeitschrift fur induktive Abstammungs- und Vererbungslehre.

[20]  G. Morata,et al.  Minutes: mutants of drosophila autonomously affecting cell division rate. , 1975, Developmental biology.

[21]  P. M. Shelton,et al.  Structure and development of ommatidia in Oncopeltus fasciatus. , 1974, Journal of embryology and experimental morphology.

[22]  J. Haendle.  [X-ray induced mitotic recombination in Drosophila melanogaster. I. Its dependence on dose, dose-rate and spectrum]. , 1971, Molecular & general genetics : MGG.