Indication for Anterior Temporal Lobectomy in Patients with Temporal Lobe Epilepsy and Psychopathology

Summary: The chronicity and severity of epilepsy, as well as the presence of temporal lobe foci, appear to correlate with psychopathology. A high prevalence of psychopathology has been reported among patients who are candidates for anterior temporal lobectomy (ATL). A review of the literature indicates that episodic psychosis may diminish when patients become free of seizures after surgery and that chronic psychosis neither improves nor worsens after ATL. If this is the case, patients with episodic psychosis may benefit from ATL. Patients with chronic psychosis may benefit if they become free from seizures after the operation, even if the psychosis persists. Case reports of maladjustment to seizure‐free life after surgery, and de novo psychopathology, underline the importance of preop‐erative psychiatric evaluation and postoperative psychiatric intervention in patients undergoing epilepsy surgery. Although there is a need for each epilepsy center to state its policy with regard to patients with psychopathology who undergo epilepsy surgery, it would be unwise to make a decision on whether to reject a patient simply on the grounds of psychosis. A detailed psychiatric evaluation of each individual patient is required.