CD81 Controls Beige Fat Progenitor Cell Growth and Energy Balance via FAK Signaling

[1]  P. Scherer,et al.  Cellular Origins of Beige Fat Cells Revisited , 2019, Diabetes.

[2]  S. Kajimura,et al.  Mitochondrial lipoylation integrates age-associated decline in brown fat thermogenesis , 2019, Nature metabolism.

[3]  Michael T. McManus,et al.  BCAA catabolism in brown fat controls energy homeostasis through SLC25A44 , 2019, Nature.

[4]  Kyoung-Jae Won,et al.  A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate. , 2019, Cell metabolism.

[5]  Ivona Percec,et al.  Identification of a mesenchymal progenitor cell hierarchy in adipose tissue , 2019, Science.

[6]  P. O’Brien,et al.  Identification of Metabolically Distinct Adipocyte Progenitor Cells in Human Adipose Tissues. , 2019, Cell reports.

[7]  Edward T Chouchani,et al.  Metabolic adaptation and maladaptation in adipose tissue , 2019, Nature Metabolism.

[8]  B. Spiegelman,et al.  Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors , 2018, Cell.

[9]  S. Kajimura,et al.  Thermal stress induces glycolytic beige fat formation via a myogenic state , 2018, Nature.

[10]  G. Hon,et al.  Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice , 2018, eLife.

[11]  P. Westgate,et al.  Human adipose beiging in response to cold and mirabegron. , 2018, JCI insight.

[12]  R. Pique-Regi,et al.  Deconstructing Adipogenesis Induced by β3-Adrenergic Receptor Activation with Single-Cell Expression Profiling. , 2018, Cell metabolism.

[13]  Petra C. Schwalie,et al.  A stromal cell population that inhibits adipogenesis in mammalian fat depots , 2018, Nature.

[14]  A. Schafer,et al.  Subcutaneous Fat Fibrosis Links Obesity to Insulin Resistance in Chinese Americans , 2018, The Journal of clinical endocrinology and metabolism.

[15]  S. Farmer,et al.  Myocardin-Related Transcription Factor A Promotes Recruitment of ITGA5+ Profibrotic Progenitors during Obesity-Induced Adipose Tissue Fibrosis. , 2018, Cell reports.

[16]  A. Rissanen,et al.  Adipose tissue mitochondrial capacity associates with long-term weight loss success , 2018, International Journal of Obesity.

[17]  S. Kajimura,et al.  Repression of Adipose Tissue Fibrosis through a PRDM16-GTF2IRD1 Complex Improves Systemic Glucose Homeostasis. , 2018, Cell metabolism.

[18]  S. Kajimura,et al.  UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis , 2017, Nature Medicine.

[19]  N. Gray,et al.  The C-terminal fibrinogen-like domain of angiopoietin-like 4 stimulates adipose tissue lipolysis and promotes energy expenditure , 2017, The Journal of Biological Chemistry.

[20]  J. Gillette,et al.  Tetraspanins Function as Regulators of Cellular Signaling , 2017, Front. Cell Dev. Biol..

[21]  K. Clément,et al.  A PDGFRα-Mediated Switch toward CD9high Adipocyte Progenitors Controls Obesity-Induced Adipose Tissue Fibrosis. , 2017, Cell metabolism.

[22]  M. Kyba,et al.  Erratum: Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans (Cell Metabolism (2017) 25(1) (166–181) (S1550413116305551)(10.1016/j.cmet.2016.10.023)) , 2017 .

[23]  M. Woo,et al.  FAK signalling controls insulin sensitivity through regulation of adipocyte survival , 2017, Nature Communications.

[24]  N. Lundbom,et al.  Mitochondria-related transcriptional signature is downregulated in adipocytes in obesity: a study of young healthy MZ twins , 2017, Diabetologia.

[25]  May-yun Wang,et al.  Pdgfrβ+ Mural Preadipocytes Contribute to Adipocyte Hyperplasia Induced by High-Fat-Diet Feeding and Prolonged Cold Exposure in Adult Mice. , 2016, Cell metabolism.

[26]  J. Graff,et al.  Mouse strains to study cold-inducible beige progenitors and beige adipocyte formation and function , 2016, Nature Communications.

[27]  Gwendolyn M. Jang,et al.  Meta- and Orthogonal Integration of Influenza "OMICs" Data Defines a Role for UBR4 in Virus Budding. , 2015, Cell host & microbe.

[28]  S. Kajimura,et al.  Phosphoproteomics Identifies CK2 as a Negative Regulator of Beige Adipocyte Thermogenesis and Energy Expenditure. , 2015, Cell metabolism.

[29]  Bruce M. Spiegelman,et al.  Brown and Beige Fat: Physiological Roles beyond Heat Generation. , 2015, Cell metabolism.

[30]  T. Yuen,et al.  The myokine irisin increases cortical bone mass , 2015, Proceedings of the National Academy of Sciences.

[31]  L. Sidossis,et al.  Genetic and functional characterization of clonally derived adult human brown adipocytes , 2015, Nature Medicine.

[32]  S. Farmer,et al.  Myocardin-Related Transcription Factor A Regulates Conversion of Progenitors to Beige Adipocytes , 2015, Cell.

[33]  J. Granneman,et al.  Cellular origins of cold‐induced brown adipocytes in adult mice , 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[34]  J. Chang,et al.  ThermoMouse: an in vivo model to identify modulators of UCP1 expression in brown adipose tissue. , 2014, Cell reports.

[35]  C. Théry,et al.  Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. , 2014, Annual review of cell and developmental biology.

[36]  D. Guertin,et al.  Adipocytes arise from multiple lineages that are heterogeneously and dynamically distributed , 2014, Nature Communications.

[37]  B. Spiegelman,et al.  A smooth muscle-like origin for beige adipocytes. , 2014, Cell metabolism.

[38]  Alexander S. Banks,et al.  Ablation of PRDM16 and Beige Adipose Causes Metabolic Dysfunction and a Subcutaneous to Visceral Fat Switch , 2014, Cell.

[39]  Felix M Mottaghy,et al.  Cold acclimation recruits human brown fat and increases nonshivering thermogenesis. , 2013, The Journal of clinical investigation.

[40]  T. Iwanaga,et al.  Recruited brown adipose tissue as an antiobesity agent in humans. , 2013, The Journal of clinical investigation.

[41]  M. Borga,et al.  Evidence for two types of brown adipose tissue in humans , 2013, Nature Medicine.

[42]  S. Kajimura,et al.  Isolation and differentiation of stromal vascular cells to beige/brite cells. , 2013, Journal of visualized experiments : JoVE.

[43]  A. Bruckbauer,et al.  The actin and tetraspanin networks organize receptor nanoclusters to regulate B cell receptor-mediated signaling. , 2013, Immunity.

[44]  T. Kelly,et al.  Assessment of abdominal fat compartments using DXA in premenopausal women from anorexia nervosa to morbid obesity , 2013, Obesity.

[45]  Ryan Berry,et al.  Characterization of the adipocyte cellular lineage in vivo , 2013, Nature Cell Biology.

[46]  S. Kajimura,et al.  Human BAT Possesses Molecular Signatures That Resemble Beige/Brite Cells , 2012, PloS one.

[47]  B. Spiegelman,et al.  Beige Adipocytes Are a Distinct Type of Thermogenic Fat Cell in Mouse and Human , 2012, Cell.

[48]  Yun-Hee Lee,et al.  In vivo identification of bipotential adipocyte progenitors recruited by β3-adrenoceptor activation and high-fat feeding. , 2012, Cell metabolism.

[49]  Shingo Kajimura,et al.  PPARγ agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein. , 2012, Cell metabolism.

[50]  S. Linnarsson,et al.  Highly Parallel Genome-Wide Expression Analysis of Single Mammalian Cells , 2012, PloS one.

[51]  B. Spiegelman,et al.  A PGC1α-dependent myokine that drives browning of white fat and thermogenesis , 2012, Nature.

[52]  L. Luo,et al.  Site-specific integrase-mediated transgenesis in mice via pronuclear injection , 2011, Proceedings of the National Academy of Sciences.

[53]  B. Spiegelman,et al.  Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice. , 2011, The Journal of clinical investigation.

[54]  A. Wagers,et al.  Identification of inducible brown adipocyte progenitors residing in skeletal muscle and white fat , 2010, Proceedings of the National Academy of Sciences.

[55]  J. L. Ding,et al.  Angiopoietin-like 4 interacts with integrins beta1 and beta5 to modulate keratinocyte migration. , 2010, The American journal of pathology.

[56]  Robert V Farese,et al.  DGAT1-dependent triacylglycerol storage by macrophages protects mice from diet-induced insulin resistance and inflammation. , 2010, The Journal of clinical investigation.

[57]  R. Weinberg,et al.  Integrin β1-focal adhesion kinase signaling directs the proliferation of metastatic cancer cells disseminated in the lungs , 2009, Proceedings of the National Academy of Sciences.

[58]  S. Finnemann,et al.  Tetraspanin CD81 is required for the αvβ5-integrin-dependent particle-binding step of RPE phagocytosis , 2007, Journal of Cell Science.

[59]  D. Sheppard,et al.  Integrin αvβ5 Regulates Lung Vascular Permeability and Pulmonary Endothelial Barrier Function , 2007 .

[60]  S. Levy,et al.  The Tetraspanin CD81 Is Necessary for Partitioning of Coligated CD19/CD21-B Cell Antigen Receptor Complexes into Signaling-Active Lipid Rafts 1 , 2004, The Journal of Immunology.

[61]  M. Quon,et al.  Repeatability characteristics of simple indices of insulin resistance: implications for research applications. , 2001, The Journal of clinical endocrinology and metabolism.

[62]  K. Walsh,et al.  Emergence of brown adipocytes in white fat in mice is under genetic control. Effects on body weight and adiposity. , 1998, The Journal of clinical investigation.

[63]  M. Zutter,et al.  Characterization of novel complexes on the cell surface between integrins and proteins with 4 transmembrane domains (TM4 proteins). , 1996, Molecular biology of the cell.

[64]  R. Levy,et al.  TAPA-1, the target of an antiproliferative antibody, defines a new family of transmembrane proteins , 1990, Molecular and cellular biology.

[65]  M. Ashwell,et al.  Brown adipose tissue in the parametrial fat pad of the mouse , 1984, FEBS letters.

[66]  M. Ruth A PGC1–α–dependent myokine that drives brown–fat–like development of white fat and thermogenesis , 2012 .

[67]  R. Muniyappa,et al.  Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage. , 2008, American journal of physiology. Endocrinology and metabolism.

[68]  RESEARCH ARTICLE Biomarkers in Lung Diseases: From Pathogenesis to Prediction to New Therapies Fra-2 negatively regulates postnatal alveolar septation by modulating myofibroblast function , 2022 .