Fluxanalyzer: A Graphical Interface for Stoichiometric and Quantitative Analysis of Metabolic Networks

Abstract Metabolic Flux Analysis has turned out to be a powerful approach for studying and engineering metabolic networks. Nevertheless, there seems to be a lack of a comprehensive software platform where all computational routines for metabolite balancing and stoichiometric analysis can be used in a convenient way. Therefore, the FluxAnalyzer, a programming package for MATLAB, was developed. The interactive software allows a menu-driven use of various procedures within a graphical user interface, where the metabolic networks under investigation and the results of calculations are visualized in flux maps. Arbitrary networks can be defined symbolically. The FluxAnalyzer is used in current projects at our institute and its application for flux analysis of cell cultures in an industrial process is planned