Highly Reactive and Regenerable Fluorinating Agent for Oxidative Fluorination of Aromatics

A newly synthesized copper aluminum fluoride of nominal composition CuAl2F8 exhibits excellent reactivity towards direct oxidative fluorination of aromatic compounds, as well as fluorodechlorination of chloroaromatics. The spent CuAl2F8 reagent can be regenerated by treatment with O2 and HF, and the fluorination process has been demonstrated to retain high conversions through 20 reaction cycles. The main advantages of this new process are safety, minimal waste, and potentially low cost.

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