Population stratification and spurious allelic association

[1]  James J Schlesselman.  Case-Control Studies: Design, Conduct, Analysis , 1982 .

[2]  Weitkamp Lr.  Genetic analysis of multifactorial diseases. , 1983 .

[3]  Dwight Lemon,et al.  Randomised trial of intravenous atenolol among 16,027 cases of suspected acute myocardial infarction: ISIS-1 , 1987 .

[4]  R. Williams,et al.  Gm3;5,13,14 and type 2 diabetes mellitus: an association in American Indians with genetic admixture. , 1988, American journal of human genetics.

[5]  K. Weiss,et al.  Admixture as a tool for finding linked genes and detecting that difference from allelic association between loci. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[6]  M. Slatkin.  Inbreeding coefficients and coalescence times. , 1991, Genetical research.

[7]  E. Riboli,et al.  Nutrition and cancer: background and rationale of the European Prospective Investigation into Cancer and Nutrition (EPIC). , 1992, Annals of oncology : official journal of the European Society for Medical Oncology.

[8]  W. Ewens,et al.  Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM). , 1993, American journal of human genetics.

[9]  C. Pato,et al.  Review of the putative association of dopamine D2 receptor and alcoholism: a meta-analysis. , 1993, American journal of medical genetics.

[10]  N Risch,et al.  The A1 allele at the D2 dopamine receptor gene and alcoholism. A reappraisal. , 1993, JAMA.

[11]  R. Cann.  The history and geography of human genes , 1995, The Journal of Asian Studies.

[12]  A. Piazza.  History and Geography of Human Genes , 1994 .

[13]  J. Stephens,et al.  Mapping by admixture linkage disequilibrium in human populations: limits and guidelines. , 1994, American journal of human genetics.

[14]  D E Weeks,et al.  Polygenic disease: methods for mapping complex disease traits. , 1995, Trends in genetics : TIG.

[15]  W. Ewens,et al.  The transmission/disequilibrium test: history, subdivision, and admixture. , 1995, American journal of human genetics.

[16]  N Risch,et al.  The Future of Genetic Studies of Complex Human Diseases , 1996, Science.

[17]  P. McKeigue,et al.  Mapping genes underlying ethnic differences in disease risk by linkage disequilibrium in recently admixed populations. , 1997, American journal of human genetics.

[18]  Francis S. Collins,et al.  Variations on a Theme: Cataloging Human DNA Sequence Variation , 1997, Science.

[19]  Simon Ball,et al.  Pharmacogenetics and drug metabolism , 1997, Nature Biotechnology.

[20]  J Drews,et al.  The role of innovation in drug development. , 1997, Nature biotechnology.

[21]  P. McKeigue,et al.  Mapping genes that underlie ethnic differences in disease risk: methods for detecting linkage in admixed populations, by conditioning on parental admixture. , 1998, American journal of human genetics.

[22]  N Risch,et al.  The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases I. DNA pooling. , 1998, Genome research.

[23]  C. Nusbaum,et al.  Large-scale identification, mapping, and genotyping of single-nucleotide polymorphisms in the human genome. , 1998, Science.

[24]  N E Morton,et al.  Tests and estimates of allelic association in complex inheritance. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[25]  Freely associating , 1999, Nature Genetics.

[26]  J. Witte,et al.  Family-based association studies. , 1999, Journal of the National Cancer Institute. Monographs.

[27]  N Risch,et al.  The relative power of family-based and case-control designs for linkage disequilibrium studies of complex human diseases. II. Individual genotyping. , 1999, Genome research.

[28]  The ESUB-MG Study Group.  The Million Women Study: design and characteristics of the study population , 1999, Breast Cancer Research.

[29]  J. Pritchard,et al.  Use of unlinked genetic markers to detect population stratification in association studies. , 1999, American journal of human genetics.

[30]  J. Witte,et al.  Asymptotic bias and efficiency in case-control studies of candidate genes and gene-environment interactions: basic family designs. , 1999, American journal of epidemiology.

[31]  K. Roeder,et al.  Genomic Control for Association Studies , 1999, Biometrics.

[32]  N. Risch.  Searching for genetic determinants in the new millennium , 2000, Nature.

[33]  R. March.  Pharmacogenomics: The Genomics of Drug Response , 2000, Yeast.

[34]  K. Roeder,et al.  The power of genomic control. , 2000, American journal of human genetics.

[35]  K. Weiss,et al.  How many diseases does it take to map a gene with SNPs? , 2000, Nature Genetics.

[36]  A. Roses,et al.  Pharmacogenetics and future drug development and delivery , 2000, The Lancet.

[37]  J. Carpenter,et al.  Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: application to African-American populations. , 2000, Annals of human genetics.

[38]  A. Roses.  Pharmacogenetics and the practice of medicine , 2000, Nature.

[39]  L. Jorde,et al.  Linkage disequilibrium and the search for complex disease genes. , 2000, Genome research.

[40]  W. Cookson,et al.  Genomic approaches to understanding asthma. , 2000, Genome research.

[41]  Li Wan Po,et al.  Pharmacogenetics and psychopharmacotherapy , 2000, Journal of clinical pharmacy and therapeutics.

[42]  E. Silverman,et al.  Case-control association studies for the genetics of complex respiratory diseases. , 2000, American journal of respiratory cell and molecular biology.

[43]  Rolf Hilfiker,et al.  The use of single-nucleotide polymorphism maps in pharmacogenomics , 2000, Nature Biotechnology.

[44]  N. Rothman,et al.  Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias. , 2000, Journal of the National Cancer Institute.

[45]  G. Abecasis,et al.  Pedigree tests of transmission disequilibrium , 2000, European Journal of Human Genetics.

[46]  J. Witte,et al.  Linkage disequilibrium and allele-frequency distributions for 114 single-nucleotide polymorphisms in five populations. , 2000, American journal of human genetics.

[47]  P. Donnelly,et al.  Inference of population structure using multilocus genotype data. , 2000, Genetics.

[48]  P. Donnelly,et al.  Association mapping in structured populations. , 2000, American journal of human genetics.

[49]  G A Satten,et al.  Accounting for unmeasured population substructure in case-control studies of genetic association using a novel latent-class model. , 2001, American journal of human genetics.

[50]  David Clayton,et al.  Epidemiological methods for studying genes and environmental factors in complex diseases , 2001, The Lancet.

[51]  M. Daly,et al.  A map of human genome sequence variation containing 1.42 million single nucleotide polymorphisms , 2001, Nature.

[52]  P. Donnelly,et al.  Case-control studies of association in structured or admixed populations. , 2001, Theoretical population biology.

[53]  R. Nichols,et al.  A method for distinguishing consanguinity and population substructure using multilocus genotype data. , 2001, Molecular biology and evolution.

[54]  J. Ott,et al.  A transmission/disequilibrium test that allows for genotyping errors in the analysis of single-nucleotide polymorphism data. , 2001, American journal of human genetics.

[55]  S. Sullivan,et al.  The health economics of asthma and rhinitis. I. Assessing the economic impact. , 2001, The Journal of allergy and clinical immunology.

[56]  H. Deng,et al.  Population admixture may appear to mask, change or reverse genetic effects of genes underlying complex traits. , 2001, Genetics.

[57]  David B. Goldstein,et al.  Population genetic structure of variable drug response , 2001, Nature Genetics.

[58]  J. Ioannidis,et al.  Replication validity of genetic association studies , 2001, Nature Genetics.

[59]  P. Quirke,et al.  Biology and genetics of colorectal cancer. , 2001, European journal of cancer.

[60]  B. Weir,et al.  Association studies under general disease models. , 2001, Theoretical population biology.

[61]  L. Wasserman,et al.  Genomic control, a new approach to genetic-based association studies. , 2001, Theoretical population biology.

[62]  DNA pooling, genome control and association studies. , 2001 .

[63]  J Blangero,et al.  Large upward bias in estimation of locus-specific effects from genomewide scans. , 2001, American journal of human genetics.

[64]  D. Reich,et al.  Detecting association in a case‐control study while correcting for population stratification , 2001, Genetic epidemiology.

[65]  L. Cardon,et al.  Association study designs for complex diseases , 2001, Nature Reviews Genetics.

[66]  H. McLeod.  Pharmacogenetics: more than skin deep , 2001, Nature Genetics.

[67]  R. deShazo,et al.  Atopy and Asthma , 2001 .

[68]  J. Stephens,et al.  Haplotype Variation and Linkage Disequilibrium in 313 Human Genes , 2001, Science.

[69]  K. Roeder,et al.  Unbiased methods for population‐based association studies , 2001, Genetic epidemiology.

[70]  Edward S. Buckler,et al.  Dwarf8 polymorphisms associate with variation in flowering time , 2001, Nature Genetics.

[71]  P. Wilson,et al.  Diabetes mellitus and coronary heart disease. , 2001, Endocrinology and metabolism clinics of North America.

[72]  J. V. Moran,et al.  Initial sequencing and analysis of the human genome. , 2001, Nature.

[73]  H Campbell,et al.  Gene–environment interactions—the BioBank UK study , 2002, The Pharmacogenomics Journal.

[74]  G. Radda,et al.  The need for independent scientific peer review of Biobank UK , 2002, The Lancet.

[75]  H. Wallace.  The need for independent scientific peer review of Biobank UK. , 2002, The Lancet.

[76]  L. Palmer,et al.  Pharmacogenetics of asthma. , 2002, American journal of respiratory and critical care medicine.

[77]  M. McCarthy,et al.  Susceptibility gene discovery for common metabolic and endocrine traits. , 2002, Journal of molecular endocrinology.

[78]  Kathryn Roeder,et al.  Association studies for quantitative traits in structured populations , 2002, Genetic epidemiology.

[79]  K. Lunetta,et al.  Testing for population subdivision and association in four case-control studies. , 2002, American journal of human genetics.

[80]  L. Cardon,et al.  What makes a good case-control study? Design issues for complex traits such as endometriosis. , 2002, Human reproduction.

[81]  R. Myers,et al.  Candidate-gene approaches for studying complex genetic traits: practical considerations , 2002, Nature Reviews Genetics.

[82]  R. McGinnis,et al.  Power and Efficiency of the TDT and Case-Control Design for Association Scans , 2002, Behavior genetics.

[83]  The need for independent scientific peer review of Biobank UK , 2002, The Lancet.

[84]  Katherine M Kirk,et al.  The impact of genotyping error on haplotype reconstruction and frequency estimation , 2002, European Journal of Human Genetics.

[85]  Robert C. Elston,et al.  Biostatistical genetics and genetic epidemiology , 2002 .

[86]  Thomas G Schulze,et al.  Genetic association mapping at the crossroads: which test and why? Overview and practical guidelines. , 2002, American journal of medical genetics.

[87]  L. Cardon,et al.  The application of genetics to the discovery of better medicines. , 2002, Pharmacogenomics (London).

[88]  M. Burns,et al.  Case-Control Study , 2020, Definitions.