A screening methodology based on Random Forests to improve the detection of gene–gene interactions

[1]  P. Donnelly,et al.  Genome-wide strategies for detecting multiple loci that influence complex diseases , 2005, Nature Genetics.

[2]  R W Doerge,et al.  Accounting for Variability in the Use of Permutation Testing to Detect Quantitative Trait Loci , 2000, Biometrics.

[3]  Leo Breiman,et al.  Random Forests , 2001, Machine Learning.

[4]  R. Stocco,et al.  Expression and function of NPSR1/GPRA in the lung before and after induction of asthma-like disease. , 2006, American journal of physiology. Lung cellular and molecular physiology.

[5]  Marsha Wills-Karp,et al.  Time to draw breath: asthma-susceptibility genes are identified , 2004, Nature Reviews Genetics.

[6]  Thomas J. Hudson,et al.  Characterization of a Common Susceptibility Locus for Asthma-Related Traits , 2004, Science.

[7]  Gonçalo Abecasis,et al.  Positional cloning of a novel gene influencing asthma from Chromosome 2q14 , 2003, Nature Genetics.

[8]  P. Rivière,et al.  Cloning and characterization of dipeptidyl peptidase 10, a new member of an emerging subgroup of serine proteases. , 2003, The Biochemical journal.

[9]  K. Lunetta,et al.  Identifying SNPs predictive of phenotype using random forests , 2005, Genetic epidemiology.

[10]  Jason H. Moore,et al.  Power of multifactor dimensionality reduction for detecting gene‐gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity , 2003, Genetic epidemiology.

[11]  M. Ritchie,et al.  Exploring the Performance of Multifactor Dimensionality Reduction in Large Scale SNP Studies and in the Presence of Genetic Heterogeneity among Epistatic Disease Models , 2008, Human Heredity.

[12]  David V Conti,et al.  A testing framework for identifying susceptibility genes in the presence of epistasis. , 2006, American journal of human genetics.

[13]  Jiang Gui,et al.  A computationally efficient hypothesis testing method for epistasis analysis using multifactor dimensionality reduction , 2009, Genetic epidemiology.

[14]  J. Kere,et al.  The protective effect of farm animal exposure on childhood allergy is modified by NPSR1 polymorphisms , 2008, Journal of Medical Genetics.

[15]  Jason H. Moore,et al.  The Ubiquitous Nature of Epistasis in Determining Susceptibility to Common Human Diseases , 2003, Human Heredity.

[16]  X. Estivill,et al.  Year : 2008 TNFA-308 G > A in two international population-based cohorts and risk of asthma , 2009 .

[17]  J. H. Moore,et al.  Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer. , 2001, American journal of human genetics.

[18]  J. Kere,et al.  Neuropeptide S and G protein-coupled receptor 154 modulate macrophage immune responses. , 2006, Human molecular genetics.