Salivary Gland Disorders in Children and Adolescents: A 15-year Experience

Introduction  Diseases of the salivary glands are rare in children and adolescents, with the exception of viral-induced infections. Objective  To determine the clinical course of the disease, the diagnostic procedures, the treatment and the outcome of all children and adolescents affected with salivary gland diseases at our clinic over a period of 15 years. Methods  A retrospective chart review including a long-term follow-up was conducted among 146 children and adolescents treated for salivary gland disorders from 2002 to 2016. Results  Diagnosing acute sialadenitis was easily managed by all doctors regardless of their specialty. The diagnosis of sialolithiasis was rapidly made only by otorhinolaryngologists, whereas diagnosing juvenile recurrent parotitis imposed difficulties to doctors of all specialties – resulting in a significant delay between the first occurrence of symptoms and the correct diagnosis. The severity-adjusted treatment yielded improvements in all cases, and a full recovery of 75% of the cases of sialolithiasis, 73% of the cases of juvenile recurrent parotitis, and 100% of the cases of acute sialadenitis. Conclusions  Due to their low prevalence and the lack of pathognomonic symptoms, salivary gland diseases in children and adolescents are often misdiagnosed, resulting in an unnecessarily long period of suffering despite a favorable outcome following the correct treatment.

[1]  Jameson K Mattingly,et al.  Treatment of juvenile recurrent parotitis of childhood: an analysis of effectiveness. , 2015, JAMA otolaryngology-- head & neck surgery.

[2]  H. Iro,et al.  Juvenile recurrent parotitis: A retrospective comparison of sialendoscopy versus conservative therapy , 2014, The Laryngoscope.

[3]  A. Trinidade,et al.  Salivary gland pathology in the paediatric population: implications for management and presentation of a rare case , 2014, The Journal of Laryngology & Otology.

[4]  T. Vogl,et al.  [The new S2k AWMF guideline for the treatment of obstructive sialadenitis in commented short form]. , 2013, Laryngo-Rhino-Otologie.

[5]  H. Iro,et al.  [Salivary gland diseases in childhood]. , 2014, Laryngo- rhino- otologie.

[6]  M. Benazzo,et al.  Sialendoscopy in juvenile recurrent parotitis: a review of the literature , 2013, Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale.

[7]  L. Pignataro,et al.  Modern management of juvenile recurrent parotitis. , 2012, The Journal of laryngology and otology.

[8]  A. Maresh,et al.  Sialoendoscopy in the diagnosis and management of obstructive sialadenitis , 2011, The Laryngoscope.

[9]  H. Welkoborsky [Current aspects in ultrasonography of the salivary glands]. , 2011, HNO.

[10]  H. Welkoborsky Aktuelle Aspekte der Ultraschalluntersuchung der Speicheldrüsen , 2011, HNO.

[11]  R. Laskawi,et al.  Diseases of the salivary glands in infants and adolescents , 2010, Head & face medicine.

[12]  H. Iro,et al.  Moderne Konzepte zur Diagnostik und Therapie der Sialolithiasis , 2010, HNO.

[13]  H. Iro,et al.  Die chronisch rezidivierende Parotitis , 2010, HNO.

[14]  D. Hartl,et al.  Clinical ultrasound of the salivary glands. , 2009, Otolaryngologic clinics of North America.

[15]  R. Shacham,et al.  Long-term experience with endoscopic diagnosis and treatment of juvenile recurrent parotitis. , 2009, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[16]  N. Ryu,et al.  Pediatric sialolithiasis: what is different from adult sialolithiasis? , 2007, International Journal of Pediatric Otorhinolaryngology.

[17]  R. Laskawi,et al.  Inflammatory diseases of the salivary glands in infants and adolescents. , 2006, International journal of pediatric otorhinolaryngology.

[18]  A. Paananen,et al.  Etiology of mumps-like illnesses in children and adolescents vaccinated for measles, mumps, and rubella. , 2005, The Journal of infectious diseases.

[19]  R. Shacham,et al.  Juvenile recurrent parotitis: a new method of diagnosis and treatment. , 2004, Pediatrics.

[20]  T. Lesnick,et al.  Pediatric parotid masses. , 2000, Archives of otolaryngology--head & neck surgery.

[21]  H. Wiedemann Salivary gland disorders and heredity. , 1997, American journal of medical genetics.

[22]  S. Ericson,et al.  Salivary factors in children with recurrent parotitis. Part 2: Protein, albumin, amylase, IgA, lactoferrin lysozyme and kallikrein concentrations. , 1996, Swedish dental journal.

[23]  Å. Geterud,et al.  Follow-up Study of Recurrent Parotitis in Children , 1988, The Annals of otology, rhinology, and laryngology.

[24]  K. Bullock Parotid and submandibular duct calculi in three successive generations of one family. , 1982, Postgraduate medical journal.

[25]  J. Dezort [Chronic recurrent parotitis]. , 1981, Ceskoslovenska pediatrie.

[26]  P. Laudenbach,et al.  [Recurrent parotitis in childhood]. , 1976, Revue de stomatologie et de chirurgie maxillo-faciale.