Screen for DNA-damage-responsive histone modifications identifies H3K9Ac and H3K56Ac in human cells

[1]  R. Scully A histone code for DNA repair , 2010, Nature Reviews Molecular Cell Biology.

[2]  Kirk C. Hansen,et al.  CBP / p300-mediated acetylation of histone H3 on lysine 56 , 2009, Nature.

[3]  Michael Grunstein,et al.  Histone h3 lysine 56 acetylation is linked to the core transcriptional network in human embryonic stem cells. , 2009, Molecular cell.

[4]  P. Thibault,et al.  Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP , 2008, Nature Structural &Molecular Biology.

[5]  Zhiguo Zhang,et al.  Acetylation of Histone H3 Lysine 56 Regulates Replication-Coupled Nucleosome Assembly , 2008, Cell.

[6]  Jeffrey G. Linger,et al.  Acetylated Lysine 56 on Histone H3 Drives Chromatin Assembly after Repair and Signals for the Completion of Repair , 2008, Cell.

[7]  Michael Q. Zhang,et al.  Combinatorial patterns of histone acetylations and methylations in the human genome , 2008, Nature Genetics.

[8]  Ronen Marmorstein,et al.  Fungal Rtt109 histone acetyltransferase is an unexpected structural homolog of metazoan p300/CBP , 2008, Nature Structural &Molecular Biology.

[9]  A. Emili,et al.  Chaperone Control of the Activity and Specificity of the Histone H3 Acetyltransferase Rtt109 , 2008, Molecular and Cellular Biology.

[10]  K. Scheidtmann,et al.  Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation , 2008, Nature Cell Biology.

[11]  Howard Y. Chang,et al.  SIRT6 is a histone H3 lysine 9 deacetylase that modulates telomeric chromatin , 2008, Nature.

[12]  B. Gómez-González,et al.  Genome instability: a mechanistic view of its causes and consequences , 2008, Nature Reviews Genetics.

[13]  N. Tanner,et al.  Single-molecule studies of fork dynamics in Escherichia coli DNA replication , 2008, Nature Structural &Molecular Biology.

[14]  Makoto Nakanishi,et al.  Chk1 Is a Histone H3 Threonine 11 Kinase that Regulates DNA Damage-Induced Transcriptional Repression , 2008, Cell.

[15]  J Wade Harper,et al.  The DNA damage response: ten years after. , 2007, Molecular cell.

[16]  Laurence Pelletier,et al.  Orchestration of the DNA-Damage Response by the RNF8 Ubiquitin Ligase , 2007, Science.

[17]  Michael B. Yaffe,et al.  RNF8 Transduces the DNA-Damage Signal via Histone Ubiquitylation and Checkpoint Protein Assembly , 2007, Cell.

[18]  Jiri Bartek,et al.  RNF8 Ubiquitylates Histones at DNA Double-Strand Breaks and Promotes Assembly of Repair Proteins , 2007, Cell.

[19]  Kevin Camphausen,et al.  Inhibition of histone deacetylation: a strategy for tumor radiosensitization. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[20]  D. Koshland,et al.  DNA Double-Strand Breaks Trigger Genome-Wide Sister-Chromatid Cohesion Through Eco1 (Ctf7) , 2007, Science.

[21]  K. Shirahige,et al.  Postreplicative Formation of Cohesion Is Required for Repair and Induced by a Single DNA Break , 2007, Science.

[22]  M. Nussenzweig,et al.  Chromatin dynamics and the preservation of genetic information , 2007, Nature.

[23]  M. Grunstein,et al.  Functions of site-specific histone acetylation and deacetylation. , 2007, Annual review of biochemistry.

[24]  T. Misteli,et al.  The ATM repair pathway inhibits RNA polymerase I transcription in response to chromosome breaks , 2007, Nature.

[25]  C. Allis,et al.  Extraction, purification and analysis of histones , 2007, Nature Protocols.

[26]  B. A. Ballif,et al.  ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage , 2007, Science.

[27]  S. Berger The complex language of chromatin regulation during transcription , 2007, Nature.

[28]  S. Jackson,et al.  Regulation of Histone H3 Lysine 56 Acetylation in Schizosaccharomyces pombe* , 2007, Journal of Biological Chemistry.

[29]  Takashi Ito Role of histone modification in chromatin dynamics. , 2007, Journal of biochemistry.

[30]  Y. Ohkuma,et al.  Phosphorylation of the C-terminal domain of RNA polymerase II plays central roles in the integrated events of eucaryotic gene expression. , 2007, Journal of biochemistry.

[31]  S. Grewal,et al.  Distinct roles of HDAC complexes in promoter silencing, antisense suppression and DNA damage protection , 2007, Nature Structural &Molecular Biology.

[32]  Grant W. Brown,et al.  Functional dissection of protein complexes involved in yeast chromosome biology using a genetic interaction map , 2007, Nature.

[33]  B. Garcia,et al.  Organismal Differences in Post-translational Modifications in Histones H3 and H4* , 2007, Journal of Biological Chemistry.

[34]  Nir Friedman,et al.  Dynamics of Replication-Independent Histone Turnover in Budding Yeast , 2007, Science.

[35]  T. Kouzarides Chromatin Modifications and Their Function , 2007, Cell.

[36]  Alain Verreault,et al.  Chromatin Challenges during DNA Replication and Repair , 2007, Cell.

[37]  Robert Driscoll,et al.  Yeast Rtt109 Promotes Genome Stability by Acetylating Histone H3 on Lysine 56 , 2007, Science.

[38]  Junhong Han,et al.  Rtt109 Acetylates Histone H3 Lysine 56 and Functions in DNA Replication , 2007, Science.

[39]  Jessica Schneider,et al.  Rtt109 Is Required for Proper H3K56 Acetylation , 2006, Journal of Biological Chemistry.

[40]  Nancy L. Maas,et al.  Taking It Off: Regulation of H3 K56 Acetylation by Hst3 and Hst4 , 2006, Cell cycle.

[41]  Y. Shiloh,et al.  Chromatin relaxation in response to DNA double-strand breaks is modulated by a novel ATM- and KAP-1 dependent pathway , 2006, Nature Cell Biology.

[42]  J. Boeke,et al.  The Sirtuins Hst3 and Hst4p Preserve Genome Integrity by Controlling Histone H3 Lysine 56 Deacetylation , 2006, Current Biology.

[43]  Nancy L. Maas,et al.  Cell cycle and checkpoint regulation of histone H3 K56 acetylation by Hst3 and Hst4. , 2006, Molecular cell.

[44]  S. Jackson,et al.  gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes. , 2006, DNA repair.

[45]  Hengbin Wang,et al.  Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. , 2006, Molecular cell.

[46]  Jiri Bartek,et al.  Spatial organization of the mammalian genome surveillance machinery in response to DNA strand breaks , 2006, The Journal of cell biology.

[47]  K. Camphausen,et al.  Histone deacetylation as a target for radiosensitization. , 2006, Current topics in developmental biology.

[48]  David Hawke,et al.  A role for cell-cycle-regulated histone H3 lysine 56 acetylation in the DNA damage response , 2005, Nature.

[49]  T. Ludwig,et al.  Involvement of Human MOF in ATM Function , 2005, Molecular and Cellular Biology.

[50]  J. Hayes,et al.  Chromatin in need of a fix: phosphorylation of H2AX connects chromatin to DNA repair. , 2005, Molecular cell.

[51]  M. Grunstein,et al.  Acetylation in Histone H3 Globular Domain Regulates Gene Expression in Yeast , 2005, Cell.

[52]  N. Curtin,et al.  Identification and Characterization of a Novel and Specific Inhibitor of the Ataxia-Telangiectasia Mutated Kinase ATM , 2004, Cancer Research.

[53]  J. Bartek,et al.  Mammalian cell cycle checkpoints: signalling pathways and their organization in space and time. , 2004, DNA repair.

[54]  Michael A. Freitas,et al.  Application of mass spectrometry to the identification and quantification of histone post‐translational modifications , 2004, Journal of cellular biochemistry.

[55]  Oscar Fernandez-Capetillo,et al.  Phosphorylation of Histone H2B at DNA Double-Strand Breaks , 2004, The Journal of experimental medicine.

[56]  Ali Jazayeri,et al.  Saccharomyces cerevisiae Sin3p facilitates DNA double-strand break repair. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[57]  J. Martens,et al.  Partitioning and plasticity of repressive histone methylation states in mammalian chromatin. , 2003, Molecular cell.

[58]  J. Milner,et al.  Loss of p53 has site-specific effects on histone H3 modification, including serine 10 phosphorylation important for maintenance of ploidy. , 2003, Cancer research.

[59]  L. Latonen,et al.  Cell cycle arrest and apoptosis provoked by UV radiation-induced DNA damage are transcriptionally highly divergent responses. , 2003, Nucleic acids research.

[60]  R. Bonner,et al.  Histone H2AX phosphorylation is dispensable for the initial recognition of DNA breaks , 2003, Nature Cell Biology.

[61]  C. Allis,et al.  Synergistic coupling of histone H3 phosphorylation and acetylation in response to epidermal growth factor stimulation. , 2000, Molecular cell.

[62]  T. Richmond,et al.  Expression and purification of recombinant histones and nucleosome reconstitution. , 1999, Methods in molecular biology.

[63]  E. Rogakou,et al.  DNA Double-stranded Breaks Induce Histone H2AX Phosphorylation on Serine 139* , 1998, The Journal of Biological Chemistry.

[64]  R. Paro,et al.  Analysis of chromatin structure by in vivo formaldehyde cross-linking. , 1997, Methods.

[65]  S. Berger,et al.  Histone acetyltransferase activity is conserved between yeast and human GCN5 and is required for complementation of growth and transcriptional activation , 1997, Molecular and cellular biology.

[66]  J. Dodge,et al.  Wortmannin, a potent and selective inhibitor of phosphatidylinositol-3-kinase. , 1994, Cancer research.

[67]  L. Hartwell,et al.  Checkpoints: controls that ensure the order of cell cycle events. , 1989, Science.

[68]  M. Smerdon,et al.  Changes in nuclear protein acetylation in u.v.-damaged human cells. , 1986, Carcinogenesis.