A Roadmap for the Production of a GMP-Compatible Cell Bank of Allogeneic Bone Marrow-Derived Clonal Mesenchymal Stromal Cells for Cell Therapy Applications

[1]  Cheolju Lee,et al.  Comparative Proteomic Analysis of the Mesenchymal Stem Cells Secretome from Adipose, Bone Marrow, Placenta and Wharton’s Jelly , 2021, International journal of molecular sciences.

[2]  C. Hewitt,et al.  Expansion of human mesenchymal stem/stromal cells on temporary liquid microcarriers , 2020, Journal of chemical technology and biotechnology.

[3]  F. Vizoso,et al.  Functional heterogeneity of mesenchymal stem cells from natural niches to culture conditions: implications for further clinical uses , 2020, Cellular and Molecular Life Sciences.

[4]  J. Karp,et al.  Shattering barriers toward clinically meaningful MSC therapies , 2020, Science Advances.

[5]  T. Heng,et al.  Biological Considerations in Scaling Up Therapeutic Cell Manufacturing , 2020, Frontiers in Pharmacology.

[6]  Zhongmin Liu,et al.  Senescence in Mesenchymal Stem Cells: Functional Alterations, Molecular Mechanisms, and Rejuvenation Strategies , 2020, Frontiers in Cell and Developmental Biology.

[7]  Keshav Rajarshi,et al.  Combating COVID-19 with mesenchymal stem cell therapy , 2020, Biotechnology Reports.

[8]  J. Ankrum,et al.  Editorial: Safety, Efficacy and Mechanisms of Action of Mesenchymal Stem Cell Therapies , 2020, Frontiers in Immunology.

[9]  S. Cramer,et al.  Phase I/II Study of Safety and Preliminary Efficacy of Intravenous Allogeneic Mesenchymal Stem Cells in Chronic Stroke. , 2019, Stroke.

[10]  D. Hommes,et al.  Long-term Evaluation of Allogeneic Bone Marrow-derived Mesenchymal Stromal Cell Therapy for Crohn’s Disease Perianal Fistulas , 2019, Journal of Crohn's & colitis.

[11]  P. Genever,et al.  Nomenclature and heterogeneity: consequences for the use of mesenchymal stem cells in regenerative medicine , 2019, Regenerative medicine.

[12]  K. V. Van Vliet,et al.  Emergent heterogeneity in putative mesenchymal stem cell colonies: Single-cell time lapsed analysis , 2019, PloS one.

[13]  M. Exline,et al.  Treatment with allogeneic mesenchymal stromal cells for moderate to severe acute respiratory distress syndrome (START study): a randomised phase 2a safety trial. , 2019, The Lancet. Respiratory medicine.

[14]  J. Ankrum,et al.  Manufacturing of primed mesenchymal stromal cells for therapy , 2019, Nature Biomedical Engineering.

[15]  M. Vasei,et al.  Safety and efficacy of allogenic placental mesenchymal stem cells for treating knee osteoarthritis: a pilot study. , 2019, Cytotherapy.

[16]  T. Yi,et al.  Transplantation of human bone marrow‐derived clonal mesenchymal stem cells reduces fibrotic scar formation in a rat spinal cord injury model , 2018, Journal of tissue engineering and regenerative medicine.

[17]  W. Gyselaers,et al.  Human Wharton's Jelly-Derived Stem Cells Display a Distinct Immunomodulatory and Proregenerative Transcriptional Signature Compared to Bone Marrow-Derived Stem Cells. , 2018, Stem cells and development.

[18]  H. Baharvand,et al.  Allogeneic cell therapy manufacturing: process development technologies and facility design options , 2017, Expert opinion on biological therapy.

[19]  K. V. Van Vliet,et al.  Concise Review: When Colonies Are Not Clones: Evidence and Implications of Intracolony Heterogeneity in Mesenchymal Stem Cells , 2016, Stem cells.

[20]  H. Tse,et al.  Mesenchymal stem cells and immunomodulation: current status and future prospects , 2016, Cell Death and Disease.

[21]  Hyunjoo Lee,et al.  Manufacture of Clinical-Grade Human Clonal Mesenchymal Stem Cell Products from Single Colony Forming Unit-Derived Colonies Based on the Subfractionation Culturing Method. , 2015, Tissue engineering. Part C, Methods.

[22]  K. Whartenby,et al.  Mesenchymal stem cells: Emerging mechanisms of immunomodulation and therapy. , 2014, World journal of stem cells.

[23]  S. Morrison,et al.  Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow. , 2014, Cell stem cell.

[24]  J. Karp,et al.  Mesenchymal stem cells: immune evasive, not immune privileged , 2014, Nature Biotechnology.

[25]  Wolfgang Wagner,et al.  Evaluation of human platelet lysate versus fetal bovine serum for culture of mesenchymal stromal cells. , 2014, Cytotherapy.

[26]  I. Weissman,et al.  Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies , 2013, Nature Medicine.

[27]  Karen Coopman,et al.  A quantitative approach for understanding small-scale human mesenchymal stem cell culture - implications for large-scale bioprocess development. , 2013, Biotechnology journal.

[28]  D. Phinney Functional heterogeneity of mesenchymal stem cells: Implications for cell therapy , 2012, Journal of cellular biochemistry.

[29]  R. Moghadasali,et al.  Intra-articular injection of autologous mesenchymal stem cells in six patients with knee osteoarthritis. , 2012, Archives of Iranian medicine.

[30]  B. Larijani,et al.  Waist Circumference, Weight, and Body Mass Index of Iranians based on National Non-Communicable Disease Risk Factors Surveillance , 2012, Iranian journal of public health.

[31]  J. Adjaye,et al.  Comparative proteome and transcriptome analyses of embryonic stem cells during embryoid body‐based differentiation , 2009, Proteomics.

[32]  J. Kang,et al.  Variations of clonal marrow stem cell lines established from human bone marrow in surface epitopes, differentiation potential, gene expression, and cytokine secretion. , 2008, Stem cells and development.

[33]  B. Sacchetti,et al.  Self-Renewing Osteoprogenitors in Bone Marrow Sinusoids Can Organize a Hematopoietic Microenvironment , 2007, Cell.

[34]  A. Uccelli,et al.  Mesenchymal stem cells: a new strategy for immunosuppression? , 2007, Trends in immunology.

[35]  D. Niederwieser,et al.  Variation in dimethyl sulfoxide use in stem cell transplantation: a survey of EBMT centres , 2005, Bone Marrow Transplantation.

[36]  S. Gronthos,et al.  Molecular and cellular characterisation of highly purified stromal stem cells derived from human bone marrow , 2003, Journal of Cell Science.

[37]  D. Soligo,et al.  Isolation of bone marrow mesenchymal stem cells by anti-nerve growth factor receptor antibodies. , 2002, Experimental hematology.

[38]  A. Böyum,et al.  Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g. , 1968, Scandinavian journal of clinical and laboratory investigation. Supplementum.