FoxO3 regulates neural stem cell homeostasis.
暂无分享,去创建一个
Alexander A. Morgan | A. Butte | A. Brunet | T. Palmer | Victoria A. Rafalski | D. Salih | N. Denko | A. Webb | Jamie O. Brett | V. Renault | S. Villeda | Pramod U. Thekkat | Camille Guillerey | Saul A. Villeda
[1] L. Chin,et al. FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. , 2009, Cell stem cell.
[2] L. Saksida,et al. A Functional Role for Adult Hippocampal Neurogenesis in Spatial Pattern Separation , 2009, Science.
[3] A. Eisch,et al. Cell-intrinsic signals that regulate adult neurogenesis in vivo: insights from inducible approaches. , 2009, BMB reports.
[4] Stefan Schreiber,et al. Association of FOXO3A variation with human longevity confirmed in German centenarians , 2009, Proceedings of the National Academy of Sciences.
[5] Ryoichiro Kageyama,et al. Roles of continuous neurogenesis in the structural and functional integrity of the adult forebrain , 2008, Nature Neuroscience.
[6] Katsuhiko Yano,et al. FOXO3A genotype is strongly associated with human longevity , 2008, Proceedings of the National Academy of Sciences.
[7] J. García-Verdugo,et al. Neural stem cells confer unique pinwheel architecture to the ventricular surface in neurogenic regions of the adult brain. , 2008, Cell stem cell.
[8] B. Roysam,et al. Adult SVZ stem cells lie in a vascular niche: a quantitative analysis of niche cell-cell interactions. , 2008, Cell stem cell.
[9] J. García-Verdugo,et al. A specialized vascular niche for adult neural stem cells. , 2008, Cell stem cell.
[10] A. Brunet,et al. FoxO transcription factors in the maintenance of cellular homeostasis during aging. , 2008, Current opinion in cell biology.
[11] F. Gage,et al. Mechanisms and Functional Implications of Adult Neurogenesis , 2008, Cell.
[12] Fred H. Gage,et al. A role for adult TLX-positive neural stem cells in learning and behaviour , 2008, Nature.
[13] T. Mak,et al. PTEN regulates p300-dependent hypoxia-inducible factor 1 transcriptional activity through Forkhead transcription factor 3a (FOXO3a) , 2008, Proceedings of the National Academy of Sciences.
[14] T. Mak,et al. FOXO3a is activated in response to hypoxic stress and inhibits HIF1-induced apoptosis via regulation of CITED2. , 2007, Molecular cell.
[15] Yoshihiro Yamanishi,et al. KEGG for linking genomes to life and the environment , 2007, Nucleic Acids Res..
[16] S. Gygi,et al. The Energy Sensor AMP-activated Protein Kinase Directly Regulates the Mammalian FOXO3 Transcription Factor* , 2007, Journal of Biological Chemistry.
[17] H. Nakauchi,et al. Foxo3a is essential for maintenance of the hematopoietic stem cell pool. , 2007, Cell stem cell.
[18] John T. Dimos,et al. shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. , 2007, Cell stem cell.
[19] Brian Keith,et al. Hypoxia-Inducible Factors, Stem Cells, and Cancer , 2007, Cell.
[20] Yonghong Xiao,et al. FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell Homeostasis , 2007, Cell.
[21] S. Armstrong,et al. FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress , 2007, Cell.
[22] S. Morrison,et al. Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing , 2006, Nature.
[23] S. Morrison,et al. Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells , 2006, Nature.
[24] Li Zhang,et al. Gene expression profiling reveals the profound upregulation of hypoxia-responsive genes in primary human astrocytes. , 2006, Physiological genomics.
[25] D. Geschwind,et al. PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[26] S. Morrison,et al. Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. , 2005, Genes & development.
[27] Brent A Reynolds,et al. Neural stem cells and neurospheres—re-evaluating the relationship , 2005, Nature Methods.
[28] D. van der Kooy,et al. p21 loss compromises the relative quiescence of forebrain stem cell proliferation leading to exhaustion of their proliferation capacity. , 2005, Genes & development.
[29] A. Bartke,et al. Increased neurogenesis in dentate gyrus of long-lived Ames dwarf mice. , 2005, Endocrinology.
[30] C. Kenyon. The Plasticity of Aging: Insights from Long-Lived Mutants , 2005, Cell.
[31] David Gems,et al. Shared Transcriptional Signature in Caenorhabditis elegans Dauer Larvae and Long-lived daf-2 Mutants Implicates Detoxification System in Longevity Assurance* , 2004, Journal of Biological Chemistry.
[32] A. Sinor,et al. Akt-1 Expression Level Regulates CNS Precursors , 2004, The Journal of Neuroscience.
[33] I. Kohane,et al. Gene regulation and DNA damage in the ageing human brain , 2004, Nature.
[34] D. Accili,et al. FoxOs at the Crossroads of Cellular Metabolism, Differentiation, and Transformation , 2004, Cell.
[35] D. Ingram,et al. Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice , 2004, Neurobiology of Aging.
[36] Ash A. Alizadeh,et al. Gene Expression Signature of Fibroblast Serum Response Predicts Human Cancer Progression: Similarities between Tumors and Wounds , 2004, PLoS biology.
[37] Hugh R. Brady,et al. The Role of HIF-1α in Transcriptional Regulation of the Proximal Tubular Epithelial Cell Response to Hypoxia* , 2003, Journal of Biological Chemistry.
[38] F. Doetsch,et al. A niche for adult neural stem cells. , 2003, Current opinion in genetics & development.
[39] Sang Chul Park,et al. Analysis of the effect of aging on the response to hypoxia by cDNA microarray , 2003, Mechanisms of Ageing and Development.
[40] P. Pandolfi,et al. PTEN in Neural Precursor Cells: Regulation of Migration, Apoptosis, and Proliferation , 2002, Molecular and Cellular Neuroscience.
[41] G. Semenza,et al. Hypoxia-inducible factor 1: oxygen homeostasis and disease pathophysiology. , 2001, Trends in molecular medicine.
[42] A. Bartke,et al. Evidence That Ames Dwarf Mice Age Differently from Their Normal Siblings in Behavioral and Learning and Memory Parameters , 2001, Hormones and Behavior.
[43] Nadine Kabbani,et al. Enhanced Proliferation, Survival, and Dopaminergic Differentiation of CNS Precursors in Lowered Oxygen , 2000, The Journal of Neuroscience.
[44] J. Vincent,et al. Importance of newly generated neurons in the adult olfactory bulb for odor discrimination. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[45] O. Kretz,et al. Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety , 1999, Nature Genetics.
[46] M. Greenberg,et al. Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor , 1999, Cell.
[47] A. Álvarez-Buylla,et al. Stem cells in the developing and adult nervous system. , 1998, Journal of neurobiology.
[48] Gerd Kempermann,et al. Experience-Induced Neurogenesis in the Senescent Dentate Gyrus , 1998, The Journal of Neuroscience.
[49] Fred H. Gage,et al. The Adult Rat Hippocampus Contains Primordial Neural Stem Cells , 1997, Molecular and Cellular Neuroscience.
[50] D. van der Kooy,et al. Transforming Growth Factor-α Null and Senescent Mice Show Decreased Neural Progenitor Cell Proliferation in the Forebrain Subependyma , 1997, The Journal of Neuroscience.
[51] S. Weiss,et al. Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. , 1992, Science.
[52] D. Yew,et al. Effects of hypoxia on the proliferation and differentiation of NSCs , 2007, Molecular Neurobiology.
[53] Adrian L. Harris,et al. Hypoxia — a key regulatory factor in tumour growth , 2002, Nature Reviews Cancer.