Seizures after flumazenil administration in a case of combined benzodiazepine and tricyclic antidepressant overdose.

Flumazenil (Anexate®, Roche, Basel, Switzerland) is a specific, high-affinity, competitive inhibitor of the central nervous system's benzodiazepine γ-aminobutyric acid receptor, with high clinical efficacy in reversing the effects of benzodiazepine overdose (1, 2). Flumazenil is used in the emergenc