A Family Based Association Study of DRD4, DAT1, and 5HTT and Continuous Traits of Attention-Deficit Hyperactivity Disorder

[1]  I. Waldman,et al.  Candidate gene studies of ADHD: a meta-analytic review , 2009, Human Genetics.

[2]  J. Gilbert,et al.  Examination of association to autism of common genetic variationin genes related to dopamine , 2008, Autism research : official journal of the International Society for Autism Research.

[3]  F. Kronenberg,et al.  On the replication of genetic associations: timing can be everything! , 2008, American journal of human genetics.

[4]  N. Laird,et al.  Family‐based association analysis of a statistically derived quantitative traits for ADHD reveal an association in DRD4 with inattentive symptoms in ADHD individuals , 2008, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[5]  L. C. Bidwell,et al.  Testing for Neuropsychological Endophenotypes in Siblings Discordant for Attention-Deficit/Hyperactivity Disorder , 2007, Biological Psychiatry.

[6]  J. Kennedy,et al.  Gene for the serotonin transporter and ADHD: No association with two functional polymorphisms , 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[7]  S. Faraone,et al.  Candidate gene studies of attention-deficit/hyperactivity disorder. , 2006, The Journal of clinical psychiatry.

[8]  J. Halperin,et al.  Elevated childhood serotonergic function protects against adolescent aggression in disruptive boys. , 2006, Journal of the American Academy of Child and Adolescent Psychiatry.

[9]  R. Hashimoto,et al.  Psychostimulant-Induced Attenuation of Hyperactivity and Prepulse Inhibition Deficits in Adcyap1-Deficient Mice , 2006, The Journal of Neuroscience.

[10]  David Goldman,et al.  Serotonin transporter promoter gain-of-function genotypes are linked to obsessive-compulsive disorder. , 2006, American journal of human genetics.

[11]  N. Laird,et al.  Family-based designs in the age of large-scale gene-association studies , 2006, Nature Reviews Genetics.

[12]  J. Nigg,et al.  The adrenergic receptor α-2A gene (ADRA2A) and neuropsychological executive functions as putative endophenotypes for childhood ADHD , 2006, Cognitive, affective & behavioral neuroscience.

[13]  E. Willcutt,et al.  The diagnostic validity of attention-deficit/hyperactivity disorder , 2005, Clinical Neuroscience Research.

[14]  J. Mill,et al.  Family‐based association study of serotonin transporter gene polymorphisms in attention deficit hyperactivity disorder: No evidence for association in UK and Taiwanese samples , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[15]  J. Nigg,et al.  Association and linkage of α-2A adrenergic receptor gene polymorphisms with childhood ADHD , 2005, Molecular Psychiatry.

[16]  Yufeng Wang,et al.  Serotonin 5‐HT1B receptor gene and attention deficit hyperactivity disorder in Chinese Han subjects , 2005, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[17]  I. Craig,et al.  Functional effects of a tandem duplication polymorphism in the 5′flanking region of the DRD4 gene , 2004, Biological Psychiatry.

[18]  G. Hsiung,et al.  A dyslexia susceptibility locus (DYX7) linked to dopamine D4 receptor (DRD4) region on chromosome 11p15.5 , 2004, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[19]  M. Posner,et al.  Assessing the molecular genetics of attention networks , 2002, BMC Neuroscience.

[20]  M. Dolan,et al.  The neuropsychology of antisocial personality disorder , 2002, Psychological Medicine.

[21]  K. Krishnan,et al.  Allelic differences in the serotonin transporter-linked polymorphic region in geriatric depression. , 2002, The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry.

[22]  S. Faraone,et al.  The nature and heritability of attention-deficit/hyperactivity disorder. , 2001, Child and adolescent psychiatric clinics of North America.

[23]  B. Pennington,et al.  Validity of the DSM-IV Subtypes of ADHD , 2001 .

[24]  J. Seibyl,et al.  Prediction of dopamine transporter binding availability by genotype: a preliminary report. , 2000, The American journal of psychiatry.

[25]  S. Nelson,et al.  Evidence for linkage of a tandem duplication polymorphism upstream of the dopamine D4 receptor gene (DRD4) with attention deficit hyperactivity disorder (ADHD) , 2000, Molecular Psychiatry.

[26]  L. Snyder,et al.  Selective reconstitution of human D4 dopamine receptor variants with Gi alpha subtypes. , 2000, Biochemistry.

[27]  R. J. Mitchell,et al.  Distribution of the 3' VNTR polymorphism in the human dopamine transporter gene in world populations. , 2000, Human biology.

[28]  H. V. Van Tol,et al.  Comparative pharmacological and functional analysis of the human dopamine D4.2 and D4.10 receptor variants. , 1999, Pharmacogenetics.

[29]  A. Paterson,et al.  Dopamine D4 Receptor Gene: Novelty or Nonsense? , 1999, Neuropsychopharmacology.

[30]  E. Bullmore,et al.  Hypofrontality in attention deficit hyperactivity disorder during higher-order motor control: a study with functional MRI. , 1999, The American journal of psychiatry.

[31]  E D Levin,et al.  Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. , 1999, Science.

[32]  J. Sirviö,et al.  Changes in activities of dopamine and serotonin systems in the frontal cortex underlie poor choice accuracy and impulsivity of rats in an attention task , 1998, Neuroscience.

[33]  N. Volkow,et al.  Dopamine transporter occupancies in the human brain induced by therapeutic doses of oral methylphenidate. , 1998, The American journal of psychiatry.

[34]  Robert Reid,et al.  Parent Ratings of Attention-Deficit/Hyperactivity Disorder Symptoms: Factor Structure and Normative Data , 1998 .

[35]  M. Mcstephen,et al.  Attention-deficit hyperactivity disorder: a category or a continuum? Genetic analysis of a large-scale twin study. , 1997, Journal of the American Academy of Child and Adolescent Psychiatry.

[36]  P. Jäkälä,et al.  Differential effects of three 5-HT receptor antagonists on the performance of rats in attentional and working memory tasks , 1997, European Neuropsychopharmacology.

[37]  L. Siever,et al.  Age-related changes in the association between serotonergic function and aggression in boys with ADHD , 1997, Biological Psychiatry.

[38]  K. Lesch,et al.  Association of Anxiety-Related Traits with a Polymorphism in the Serotonin Transporter Gene Regulatory Region , 1996, Science.

[39]  P Riederer,et al.  Allelic Variation of Human Serotonin Transporter Gene Expression , 1996, Journal of neurochemistry.

[40]  K. Kidd,et al.  The world-wide distribution of allele frequencies at the human dopamine D4 receptor locus , 1996, Human Genetics.

[41]  R. Mark Wightman,et al.  Hyperlocomotion and indifference to cocaine and amphetamine in mice lacking the dopamine transporter , 1996, Nature.

[42]  J. Biederman,et al.  DSM-IV field trials for attention deficit hyperactivity disorder in children and adolescents. , 1994, The American journal of psychiatry.

[43]  H. V. Van Tol,et al.  Dopamine D4 receptor repeat: analysis of different native and mutant forms of the human and rat genes. , 1994, Molecular pharmacology.

[44]  X Li,et al.  Human dopamine transporter gene (DAT1) maps to chromosome 5p15.3 and displays a VNTR. , 1992, Genomics.

[45]  P. Seeman,et al.  Multiple dopamine D4 receptor variants in the human population , 1992, Nature.

[46]  W. Pelham,et al.  Teacher ratings of DSM-III-R symptoms for the disruptive behavior disorders. , 1992, Journal of the American Academy of Child and Adolescent Psychiatry.

[47]  P. Lavori,et al.  The disruptive behavioral disorder in children and adolescents: comorbidity and clinical course. , 1992, Journal of the American Academy of Child and Adolescent Psychiatry.

[48]  L. C. Bidwell,et al.  Testing for Neuropsychological Endophenotypes in Siblings Discordant for ADHD , 2009 .

[49]  B. Herpertz-Dahlmann,et al.  Family-based association study of serotonergic candidate genes and attention-deficit/hyperactivity disorder in a German sample , 2006, Journal of Neural Transmission.

[50]  J. Nigg,et al.  Association and linkage of alpha-2A adrenergic receptor gene polymorphisms with childhood ADHD. , 2005, Molecular psychiatry.

[51]  L. Cardon,et al.  Genetic etiology of comorbid reading difficulties and ADHD. , 2003 .

[52]  G. Abecasis,et al.  Merlin—rapid analysis of dense genetic maps using sparse gene flow trees , 2002, Nature Genetics.

[53]  B. Madras,et al.  Polymorphisms in the 3′-untranslated region of human and monkey dopamine transporter genes affect reporter gene expression , 2002, Molecular Psychiatry.

[54]  S. Fuke,et al.  The VNTR polymorphism of the human dopamine transporter (DAT1) gene affects gene expression , 2001, The Pharmacogenomics Journal.

[55]  S. Sesack,et al.  Cellular and subcellular localization of the dopamine transporter in rat cortex. , 1998, Advances in pharmacology.

[56]  Robert Reid,et al.  Adhd Rating Scale-IV: Checklists, Norms, and Clinical Interpretation , 1998 .

[57]  Kevin R. Murphy,et al.  Attention-deficit hyperactivity disorder: A clinical workbook, 2nd ed. , 1998 .

[58]  J. Defries.  Colorado Learning Disabilities Research Center , 1997 .

[59]  Kevin R. Murphy,et al.  Attention-deficit hyperactivity disorder : a clinical workbook , 1991 .

[60]  M. Posner,et al.  The attention system of the human brain. , 1990, Annual review of neuroscience.

[61]  D. Wechsler.  Manual for the Wechsler Adult Intelligence Scale. , 1955 .